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HP0254

Victor ID 354
Gene Name HP0254
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 899058
NCBI Protein GI 15644882
Locus Tag HP0254
Protein Accession NP_207052.1
Other Database IDs UniProtKB-ID: O25036_HELPY
UniRef100: UniRef100_O25036
UniRef90: UniRef90_Q1CUP9
UniRef50: UniRef50_Q1CUP9
UniParc: UPI00000D2FD3
EMBL: AE000511
EMBL-CDS: AAD07320.1
RefSeq_NT: NC_000915.1
DIP: DIP-3270N
MINT: MINT-186228
GenomeReviews: AE000511_GR
KEGG: hpy:HP0254
NMPDR: fig|85962.1.peg.250
TIGR: HP_0254
HOGENOM: HBG501626
OMA: ANIFTYG
ProtClustDB: CLSK495943
Taxonomy ID 85962
Gene Starting Position 263313
Gene Ending Position 264608
Gene Strand (Orientation) +
Protein Name outer membrane protein (omp8)
DNA Sequence 
>gi|15644634:263313-264608 Helicobacter pylori 26695, complete genome
CGTGGCGTTAGCTGAAGACGATGGCTTTTATATGGGAGTGGGCTATCAAATCGGCGGCGCGCAACAAAAT
ATCGATAACAAAGGCAGCACCCTAAGGAATAATGTCATTAATAATTTCCGCCAAGTGGGCGTGGGTATGG
CAGGGGGTAATGGGCTTTTAGCCTTAGCGACAAACACGACCATGGACGCTCTTTTAGGGATAGGCAACCA
AATTGTCAATACTAATACAACTGTTAGCAACAACAACGCAGAATTAACCCAGTTTAAAAAAATACTCCCT
CAAATTGAGCAACGCTTTGAAACGAATAAAAACGCTTATAGCGTTCAAGCCTTGCAAGTGTATTTGAGTA
ATGTGCTTTATAACTTGGTTAATAATAGTAATAATGGCAGTAATAATGGAGTCGTTCCTGAATATGTAGG
AATTATAAAAGTTCTCTATGGTTCTCAAAATGAATTCAGTCTCTTAGCCACGGAGAGTGTGGTGCTTTTA
AACGCGCTTACAAGGGTGAATCTGGATAGTAATTCGGTGTTTTTAAAAGGGCTATTAGCCCAAATGCAGC
TTTTTAATGACACTTCTTCAGCAAAGCTAGGCCAGATCGCAGAAAACTTGAAGAACGGTGGTGCAGGATC
AATGCTCCAAAAGGATGTGAAAACCATCTCGGATCGAATCGCTACTTACCAAGAGAATCTAAAACAGCTA
GGAGGGATGCTAAAGAATTACGATGAACCCTACTTGCCCCAATTTGGGCCAGGCACAAGCTCTCAGCATG
GGGTTATTAATGGCTTTGGCATTCAAGTGGGCTATAAGCAATTTTTTGGGAACAAGCGGAATATAGGCTT
ACGATATTACGCTTTCTTTGATTATGGCTTTACGCAATTGGGCAGTCTTAGCAGCGCCGTTAAAGCGAAT
ATCTTTACTTATGGCGCTGGCACGGACTTTTTATGGAATATCTTTAGAAGGGTTTTTAGCGATCAGTCCT
TGAATGTGGGGGTGTTTGGGGGCATTCAAATAGCGGGTAACACTTGGGATAGCTCTTTAAGAGGTCAAAT
TGAAAACTCGTTTAAAGAATACCCCACTCCCACGAATTTCCAATTTTTGTTTAATTTGGGTTTAAGGGCT
CATTTTGCCAGCACCATGCACCGCCGGTTTTTGAGCGCGTCTCAAAGCATTCAGCATGGGATGGAATTTG
GCGTGAAAATCCCGGCTATCAATCAAAGGTATTTGAGGGCCAATGGGGCTGATGTGGATTACAGGCGTTT
GTATGCGTTCTATATCAATTACACGATAGGTTTTTA
Protein Sequence 
>gi|15644882|ref|NP_207052.1| hypothetical protein HP0254 [Helicobacter pylori 26695] MALAEDDGFYMGVGYQIGGAQQNIDNKGSTLRNNVINNFRQVGVGMAGGNGLLALATNTTMDALLGIGNQIVNTNTTVSNNNAELTQFKKILPQIEQRFETNKNAYSVQALQVYLSNVLYNLVNNSNNGSNNGVVPEYVGIIKVLYGSQNEFSLLATESVVLLNALTRVNLDSNSVFLKGLLAQMQLFNDTSSAKLGQIAENLKNGGAGSMLQKDVKTISDRIATYQENLKQLGGMLKNYDEPYLPQFGPGTSSQHGVINGFGIQVGYKQFFGNKRNIGLRYYAFFDYGFTQLGSLSSAVKANIFTYGAGTDFLWNIFRRVFSDQSLNVGVFGGIQIAGNTWDSSLRGQIENSFKEYPTPTNFQFLFNLGLRAHFASTMHRRFLSASQSIQHGMEFGVKIPAINQRYLRANGADVDYRRLYAFYINYTIGF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP0254 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].