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tia from Escherichia coli IAI39

Victor ID 3518
Gene Name tia from Escherichia coli IAI39
Sequence Strain (Species/Organism) Escherichia coli IAI39
NCBI Gene ID 7150281
NCBI Protein GI 218702439
Locus Tag ECIAI39_4192
Protein Accession YP_002410068.1
Other Database IDs UniProtKB-ID: B7NQ34_ECO7I
UniRef100: UniRef100_Q4FBH2
UniRef90: UniRef90_Q4FBH2
UniRef50: UniRef50_Q46678
UniParc: UPI0000553297
EMBL: CU928164
EMBL-CDS: CAR20299.1
EMBL-CDS: CAR20696.1
RefSeq_NT: NC_011750.1
EnsemblGenome: EBESCG00000146720.
EnsemblGenome_TRS: EBESCT00000147412
EnsemblGenome_PRO: EBESCP00000141368
EnsemblGenome: EBESCG00000150058.
EnsemblGenome_TRS: EBESCT00000148753
EnsemblGenome_PRO: EBESCP00000141468
GenomeReviews: CU928164_GR
OMA: DNYSASK
ProtClustDB: CLSK2467286
BioCyc: E
Taxonomy ID 585057
Gene Starting Position 4366457
Gene Ending Position 4367212
Gene Strand (Orientation) -
Protein Name Tia invasion determinant
DNA Sequence 
>gi|218698419:4366457-4367212 Escherichia coli IAI39, complete genome
GTCAGAAGTTATAAGTCACACCAAACATGATGTCGTGACTTTTAACGTCAGCCTCTGATTTATATTTATC
CCCTTCTGCATCCTTGTAAGACAGGGAGGATTTACCAGCATCCAGATAGCGATAGCTGAGGTCAAGAGCG
ATATCCGGGGTTATGTCATAGCGAACACCGGCCCCAATGCTCCATGCGAAATTGTTATCATATCCCGAGT
AATGCAACGCAGAAATATCGCTCACCTCACCAGATTTATTCCAGGAGGTATCAGTATATGTTGCCTTATG
ATGTATCCGTGCATAACCCAGTCCAACAGACACCCATGGAGTGAATGCACTGCTGTTTCTGAAGTCATAA
TACGTATTCACCATCAGGGTATTCACACTGAGCCTGTTCTGTGTGTCTTCCCGACCACCATCCCCCATCG
GAGAATGCCATGTATCCAGTGTATAATGGGAGTCTGCAGCTCCGCGGCCATAGAATTCCACTTCCGTGCG
CACAGGAACATTGTAATGTTGATAAAAATCATAGCCCACCGCAAGGCCTGCACCAAATACAGTATCGTTT
TTATCACCGCCCTTATACTTATAAACATCATCCCCAAAGTCCTGACGGAAGCGCTGGTCAGTCTGAGTCA
CAACCGAAGCACCAGCTTTACCGGTCACATAAAAGCCTGTTTTACCCCTATCAGCCAGAGCCTGGGCTGA
AAATACGCCCGCCATAGCAAGCGCTGAAACAACAATAACCTTTTTCATTTCAATCA
Protein Sequence 
>gi|218702439|ref|YP_002410068.1| Tia invasion determinant [Escherichia coli IAI39] MIEMKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKGGDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQNRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHYSGYDNNFAWSIGAGVRYDITPDIALDLSYRYLDAGKSSLSYKDAEGDKYKSEADVKSHDIMFGVTYNF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tia deletion strains were noninvasive and lacked the ability to adhere to human ileocecal cells (Fleckenstein et al., 1996).
COG COG3637M, under M: Cell wall/membrane/envelope biogenesis
References
Fleckenstein et al., 1996: Fleckenstein JM, Kopecko DJ, Warren RL, Elsinghorst EA. Molecular characterization of the tia invasion locus from enterotoxigenic Escherichia coli. Infection and immunity. 1996; 64(6); 2256-2265. [PubMed: 8675335].