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ecpA from Escherichia coli UMN026

Victor ID 3513
Gene Name ecpA from Escherichia coli UMN026
Sequence Strain (Species/Organism) Escherichia coli UMN026
NCBI Gene ID 7158311
NCBI Protein GI 218703573
Locus Tag ECUMN_0327
Protein Accession YP_002411092.1
Other Database IDs UniProtKB-ID: B7N8J1_ECOLU
UniRef100: UniRef100_B7N8J1
UniRef90: UniRef90_P0C8Z9
UniRef50: UniRef50_P0C8Z9
UniParc: UPI0001888816
EMBL: CU928163
EMBL-CDS: CAR11542.1
RefSeq_NT: NC_011751.1
EnsemblGenome: EBESCG00000116438.
EnsemblGenome_TRS: EBESCT00000120757
EnsemblGenome_PRO: EBESCP00000110218
GenomeReviews: CU928163_GR
HOGENOM: HBG298879
OMA: ATWKATA
ProtClustDB: CLSK879619
BioCyc: ECOL585056:ECUMN_0327-MONOMER
Taxonomy ID 585056
Gene Starting Position 353748
Gene Ending Position 354335
Gene Strand (Orientation) -
Protein Name E. coli common pilus (ECP)
DNA Sequence 
>gi|218703261:353748-354335 Escherichia coli UMN026, complete genome
ATTAACTGGTCCAGGTCGCGTCGAACTGTACGCTAACGTCGCCGCTCCAGATGCCTTCCGGTAGAGTGCT
GTAATCGGTTACTGCGGTGGTACCATTGGTGGTGCCGCTGATGATGGAGAAAGTGAAACCATCCTGTGCG
GTGGTACGATTGCTGGCATTGTAACCGTTAGCCAGTGGGCTAAGGTTGCCGCCCAGTACGCCGTTGGCGG
TATCGATCATCACGGTATCGCCAGTTTTTTCGACTGCCGCGCCGTTATAATCCACGCCCACATTCAGTGT
GGAACCTGAGGTATCCAACTGGGTTAAGGTGTTGGTGATAAGACGTGAGGTCAGTTTAAAGGCGGTAGCC
GTTGAGTCACCCTCGATAGCCACGTCAAATAGACCTTTCTGTGAGTTAAAACCTTTAATGCCTTCGGCAT
ACTGGAACGCCAGGCTACCGAGTGGCGTCACAACCAGCTTACTGGTGGTGTCTTTTTTGGCTGTTGCTGA
CCAGGTCGCTACAGCCTGAGCTGTTACGTCAGCAGCCTGCGCCACACCTGAACCGGTAAACACCGTTACC
AGAGCTATTGCCAGAACCTTTTTTTTCA
Protein Sequence 
>gi|218703573|ref|YP_002411092.1| common pilus ECP [Escherichia coli UMN026] MKKKVLAIALVTVFTGSGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSGSTLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSIISGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ecpA mutant had attenuated adherence to HEp-2 cells compared to the parental EHEC strain (Rendón et al., 2007).
References
Rendón et al., 2007: Rendón MA, Saldaña Z, Erdem AL, Monteiro-Neto V, Vázquez A, Kaper JB, Puente JL, Girón JA. Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(25); 10637-10642. [PubMed: 17563352].