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dsbA from Escherichia coli O127:H6 str. E2348/69

Victor ID 3495
Gene Name dsbA from Escherichia coli O127:H6 str. E2348/69
Sequence Strain (Species/Organism) Escherichia coli O127:H6 str. E2348/69
NCBI Gene ID 7063974
NCBI Protein GI 215489194
Locus Tag E2348C_4167
Protein Accession YP_002331625.1
Other Database IDs UniProtKB-ID: DSBA_ECO27
UniRef100: UniRef100_P0A4L6
UniRef90: UniRef90_P0A4L6
UniRef50: UniRef50_P0A4L6
UniParc: UPI000000E973
EMBL: Z54203
EMBL: FM180568
EMBL-CDS: CAA90910.1
EMBL-CDS: CAS11715.1
RefSeq_NT: NC_011601.1
EnsemblGenome: EBESCG00000112371
EnsemblGenome_TRS: EBESCT00000115485
EnsemblGenome_PRO: EBESCP00000104995
GenomeReviews: FM180568_GR
KEGG: ecg:E2348C_4167
HOGENOM: HBG680642
OMA: CYQFEQV
ProtClustDB: PRK10954
Taxonomy ID 574521
Gene Starting Position 4359530
Gene Ending Position 4360156
Gene Strand (Orientation) +
Protein Name periplasmic protein disulfide isomerase I
DNA Sequence 
>gi|215485161:4359530-4360156 Escherichia coli O127:H6 str. E2348/69, complete genome
CATGAAAAAGATTTGGCTGGCGCTGGCTGGTTTAGTTTTAGCGTTTAGCGCATCGGCGGCGCAGTATGAA
GATGGTAAACAGTACACTACCCTGGAAAAACCAGTTGCTGGCGCGCCGCAAGTGCTGGAGTTTTTCTCTT
TCTTCTGCCCGCACTGCTATCAGTTTGAAGAAGTTCTGCATATTTCTGATAACGTGAAGAAAAAACTGCC
GGAAGGCGTGAAGATGACTAAATACCACGTCAACTTCATGGGGGGTGACCTGGGCAAAGAGCTGACTCAG
GCATGGGCTGTGGCGATGGCGCTGGGCGTGGAAGACAAAGTCACAGTTCCGCTGTTTGAAGGCGTACAAA
AAACCCAGACCATTCGTTCAGCATCTGATATCCGCGATGTATTTATCAACGCAGGTATTAAAGGTGAAGA
GTACGACGCGGCGTGGAACAGCTTCGTGGTGAAATCTCTGGTCGCTCAGCAGGAAAAAGCTGCAGCTGAC
GTGCAATTGCGTGGTGTTCCGGCGATGTTTGTTAACGGTAAATATCAGCTGAATCCGCAGGGTATGGATA
CCAGCAATATGGATGTTTTTGTTCAGCAGTATGCTGATACTGTGAAATATCTGTCCGAGAAAAAATA
Protein Sequence 
>gi|215489194|ref|YP_002331625.1| protein disulfide isomerase I [Escherichia coli O127:H6 str. E2348/69] MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKELTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutation of dsbA led to degradation of bundilin and an absence of localized adherence to host cells in EPEC (Donnenberg et al., 1997).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Donnenberg et al., 1997: Donnenberg MS, Zhang HZ, Stone KD. Biogenesis of the bundle-forming pilus of enteropathogenic Escherichia coli: reconstitution of fimbriae in recombinant E. coli and role of DsbA in pilin stability--a review. Gene. 1997; 192(1); 33-38. [PubMed: 9224871].