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espD from Escherichia coli O127:H6 str. E2348/69

Victor ID 3493
Gene Name espD from Escherichia coli O127:H6 str. E2348/69
Sequence Strain (Species/Organism) Escherichia coli O127:H6 str. E2348/69
NCBI Gene ID 7063878
NCBI Protein GI 215488966
Locus Tag E2348C_3935
Protein Accession YP_002331397.1
Other Database IDs UniProtKB-ID: B7UM93_ECO27
UniRef100: UniRef100_B7UM93
UniRef90: UniRef90_P71215
UniRef50: UniRef50_P71215
UniParc: UPI000187BE46
EMBL: FM180568
EMBL-CDS: CAS11483.1
RefSeq_NT: NC_011601.1
EnsemblGenome: EBESCG00000113534.
EnsemblGenome_TRS: EBESCT00000112883
EnsemblGenome_PRO: EBESCP00000107348
GenomeReviews: FM180568_GR
KEGG: ecg:E2348C_3935
HOGENOM: HBG468008
OMA: SARVNIR
ProtClustDB: CLSK334861
Taxonomy ID 574521
Gene Starting Position 4105917
Gene Ending Position 4107059
Gene Strand (Orientation) -
Protein Name translocon EspD
DNA Sequence 
>gi|215485161:4105917-4107059 Escherichia coli O127:H6 str. E2348/69, complete genome
ATTAAACTCGACCGCTGACAATACGGATATTCACTCGCGCAGAATCAGACATCAGCTGAGAAGCACTCTG
TATATAATTCGCCTGGTTTTGCAGCTCGAGAGTAGCTTTTTCCAGCTCTGCCTTCGCACTCTGACTTAAG
TACTCACTTTGTCGAGTTAAATTTTCCACAGCAAAAGCAGAAACCTGTGATAACACATTATAATACGCTG
CGTCATTATTCAGCACAGTTGTACCAATAGAGCGCGAAGAAGTAGTTAAACCATTTGCCACTGCCGAAAT
TTTCGATGCAACATTATCAACAAAAGTGTCGGCCAGCGTAGTGACTACTTTTACGATGTTTGAACCAACT
TTGTTAGCGACATCGCCAACTTTAGATATAAGTGAAGACACCCCGCCAATGCCGGCTGTCAGAATACCTG
CGGCAAGAGATAGACCGCCAAAAGCTTGCGCTGCTGTTTTTAACGCCTGTGGAGCATCATCGCCCATAAC
ATCAACTGCAGTTTGCAGTGCCATTGCTGTTGCACTAATAGCAACAACAGCCCAGAGTGCCGGGTTAAAA
ATAGCTGCAATAGCAGTTGCTGCAACCCCTAACCAACCAAAGACCTGACCAACAATTTTACTTTTTTGTG
CTTTCTCTTCGGCTTTTTGTTGTTCTTCGAGCTGCTTTTTAAACTCCAGCGTTTTATTATCCAGCGCTTT
ATTTTGTCCATCCGCGTAGATCTCGTTGGAGTTTTTCATACTCGCAACTCTCTGCGCTGAGGCATCCAGG
GATAACAGAGTGGCCATCATCATCATGGCCTGAGGGTCAACGTTATTCACCTGAGAAAGATAAGGATAGC
CAGAGCTTGCATTCTGAGTGCTGCGCTGTGGTTCTGTTCCCTCTGTTCGACTCGTAACTTCACCACTAAT
ACCACCAAACAGCTTACTCAGGACATCCTCAGCAGCAGAGGGCGTCACTAATGAGTGACCTGCCGGTGGC
GTTGGTAAAGCGGTACTTTCTGTCCAACTTGCTGATGGGGCCGTGGATTTAACCAGTTGTAAATCCAGCG
CGGAAGTCACTTCAGACTGATTAATACCTGAAGTAGCCGTAGCAGCACTGGCTCCAGACCTCACAGACTG
GATATCGTTATTTACATTAAGCA
Protein Sequence 
>gi|215488966|ref|YP_002331397.1| translocon EspD [Escherichia coli O127:H6 str. E2348/69] MLNVNNDIQSVRSGASAATATSGINQSEVTSALDLQLVKSTAPSASWTESTALPTPPAGHSLVTPSAAEDVLSKLFGGISGEVTSRTEGTEPQRSTQNASSGYPYLSQVNNVDPQAMMMMATLLSLDASAQRVASMKNSNEIYADGQNKALDNKTLEFKKQLEEQQKAEEKAQKSKIVGQVFGWLGVAATAIAAIFNPALWAVVAISATAMALQTAVDVMGDDAPQALKTAAQAFGGLSLAAGILTAGIGGVSSLISKVGDVANKVGSNIVKVVTTLADTFVDNVASKISAVANGLTTSSRSIGTTVLNNDAAYYNVLSQVSAFAVENLTRQSEYLSQSAKAELEKATLELQNQANYIQSASQLMSDSARVNIRIVSGRV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espD deletion mutant of the enterohemorrhagic E. coli (EHEC) strain EDL933 had impaired attachment to HeLa cells (Kresse et al., 1999).
COG COG5613S, under S: Function unknown
References
Kresse et al., 1999: Kresse AU, Rohde M, Guzmán CA. The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells. Infection and immunity. 1999; 67(9); 4834-4842. [PubMed: 10456938].