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ompA from Escherichia coli O127:H6 str. E2348/69

Victor ID 3490
Gene Name ompA from Escherichia coli O127:H6 str. E2348/69
Sequence Strain (Species/Organism) Escherichia coli O127:H6 str. E2348/69
NCBI Gene ID 7063342
NCBI Protein GI 215486075
Locus Tag E2348C_0943
Protein Accession YP_002328506.1
Other Database IDs UniProtKB-ID: B7UN36_ECO27
UniRef100: UniRef100_B7UN36
UniRef90: UniRef90_Q49P71
UniRef50: UniRef50_B7LNW7
UniParc: UPI000187B8A8
EMBL: FM180568
EMBL-CDS: CAS08491.1
RefSeq_NT: NC_011601.1
EnsemblGenome: EBESCG00000114514.
EnsemblGenome_TRS: EBESCT00000114016
EnsemblGenome_PRO: EBESCP00000107496
GenomeReviews: FM180568_GR
KEGG: ecg:E2348C_0943
HOGENOM: HBG741096
OMA: DDNEAQK
ProtClustDB: PRK10808
Taxonomy ID 574521
Gene Starting Position 1007028
Gene Ending Position 1008068
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|215485161:1007028-1008068 Escherichia coli O127:H6 str. E2348/69, complete genome
CTTAAGCCTGCGGCTGAGTTACAACGTCTTTGATGCCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAATCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATTTTGTCTGCCGGGATACCTTTAGAGATCAGGTAATCAACAACGGACTGAG
CACGACGCTCGGACAGAGCCTGGTTATAAGCGTCAGAACCGATGCGGTCAGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGGTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTACTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCATACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATACCACCCAGACGAGTGTA
TACGTCCAGATCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGCTGAACGCCCTGAGCTTTATATGCA
CCGTTTTCAACGCTGCCTTTGTATGGCATACGACCTAACCAGTCATAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGACCATTGTTAGGAAT
AAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCA
Protein Sequence 
>gi|215486075|ref|YP_002328506.1| outer membrane protein A [Escherichia coli O127:H6 str. E2348/69] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFIPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEVAPVVAPAPAPAPEVQTKHFTLKSDVLFTFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQALSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].