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flgL

Victor ID 348
Gene Name flgL
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 898810
NCBI Protein GI 15644923
Locus Tag HP0295
Protein Accession NP_207093.1
Other Database IDs UniProtKB-ID: O25068_HELPY
UniRef100: UniRef100_O25068
UniRef90: UniRef90_E1PY15
UniRef50: UniRef50_D7FF67
UniParc: UPI00000D3098
EMBL: AE000511
EMBL-CDS: AAD07364.1
RefSeq_NT: NC_000915.1
DIP: DIP-3204N
MINT: MINT-164466
GenomeReviews: AE000511_GR
KEGG: hpy:HP0295
NMPDR: fig|85962.1.peg.291
TIGR: HP_0295
HOGENOM: HBG501637
OMA: IRRNEVL
ProtClustDB: PRK08412
Taxonomy ID 85962
Gene Starting Position 312144
Gene Ending Position 314630
Gene Strand (Orientation) -
Protein Name flagellar hook-associated protein FlgL
DNA Sequence 
>gi|15644634:312144-314630 Helicobacter pylori 26695, complete genome
ATTACAAGTATTTCGTTAAAGACAAATTATTGATTTTGTTCGTGGAAGCCAAAACAGCGTTATAGTTGTT
AGTGAGATTGGAAAATTTGTTGTAAGTTTCTGCCATATCCGTGCCGGTCGTTTCCCCACGAATGCTTTGA
ACTTGCGTTTTTAAAACTTCATTACGCCTGATAATGTTCTCAAACGCCTTGCCATGAGCACCGTTTTTAG
CGATCATTTTTTCTATGTGATCGCTCAAGTGATCTATAAGGGTGATGCCGTTTTGAATGCCTAAATTACG
CATATCGCTAGAATAAGTATCCCCTAAAGCGTCCGGGCGATAAATCCCTTTTCTTACAGAAGTGATGGTA
TTTTCTAATTGATCAAAAAAATTCACGCTGGGCTTGTCAATAATGAGAGCGTTATTAGCGTTTAATTTAA
GGCTTGGTTTGTCGCTGTGCAAGGCGTTTTGAGAAAAATCATTCGCGTCTTTATCAAAAAGCATGAACTG
CATTTTGGTGTTGGAATGCATGTTATCTTGGATAATGACTTTTCCCTCTTCATTCAAATTAACAGAAAGG
TTGTCTTTAGCTTGTTTTAACAATCCAATAAAGCGCTCCTTGCTTTCTTTGGAAGTGGGGTTATCGCTGA
TTTGTTGGTAGATGGCTGGGTCAGTATTGCTGTAATTGAGCGCGATACTCATCGCATCCATAAGTTGCCT
GTAAGTGACTTCATTGGGTTTAGACGCTTGAATATCAGCGCTTGTGGGGTCATAAAGCGGGATTTTAATG
CCATTAGGGAGGCTCAAAAAAGCCCCATTATTATCCAAGTTCATTTGCGCTTCCAAAAATAAGCCATTCA
CATCGTTTAATTTCATGTTAAAAACGCTATTTTCTAAACTCCCCTTAGCGGCTTCACTCAGTTTAGTAGA
GCCATTAGCTGCGCCATTTTGAGCGGTTTGAGCGACATTGCTTTCTAATTTTGCCCCTTCTTTATTGAAG
TAGGTTTTTTGGTATTCGCTCGCGTTATTAGTAGGGATACCGGCCACTTCTAGTCCTTTAGCATCTAGGG
CGCTTAAAGCCAAAGAAATAGGCGATTCTTTAGAAGAATTGTCAATAATCCTCAAACGCCCGTTTGTTTC
AATTTCCACATCCACTTCATTATTGAAGCGTTTTTTGATCGCGTCTTTCAAATCTTTAATCGTAGAATTT
TTCACGTCTAAAAGAATGGGAATGTCCAAATAAACAGGGAGGTTTGGGATTTTAATAGCGCTTGTTTCGT
CCAAACGGCTGGCATTGATTTTTAAAGTTTCCACGCTATCGCCAAAAATCTCGCTCAATTTAGTGTTTTT
GTTGGCTAAAACATTGTCTTTAGTGACAAACACGCTAGGGACTTCAAGCACCTTGGGATTATACATGTTA
GGCACCGCTTTAACTTGGCTCAAACTCCTATCCGTTACAAACGCACTTTTGATGTATTCAGTAACCCTTT
TACCGCTCGAACGCAAGGCGTCTAAATCGTCAAAATCCCCATCGCTAGAAATCAAATGAAAATCCAAATT
TTCACTGCCGGGGGTTAGGTTTTTGATCTCAATTTGCCCCCAATTGTTCAAACTCACATCCACGACTTTA
TTTTGCGAAGTGTTCCCGTAAGCGTGAGCGATTTTATCCAACAAATCGCTCACTTTAGAGGCACTCTCTT
GGTTTTGATAGGCTTTATCCAACGCGAATTTTTCTTTAAAACTGGAGCCATCAGGCCTAACGCCTTGCAA
ATAAAAAAACTCTTTAGGGTCATTGGTGGGGTCTTTATCGTTATCGCCGATGAGTTCTCGCAAGGTATCG
CTGGGTTTAATAAAAACTTCCTCAGGCAATGAAGAATGCTCTAAAGCGTCCATCACATCAGGGTGGAGCT
TGTTTTGATTGAATAATTTAATGTTGGTGGTAATGAGTTTGTGTTTGTCTTTATCGGTGCCTAAAAACAA
ATCTTGCCCGCTGATATTATAAGGCACAAGGTTATCAGAGCTAATAAGCACGTTTAAATCTTCGCCATTG
CCATGGTATTTCCCATTACTATCAATGGGGGGTCTATCCACCTTACTGCCCCCAAATAAAAATTCCCCCC
CTATAGAAGTGTTAGCGACATTTATCATATGCTCTTTTAAGCGTTCTAAATCGTTAGCGATAGCGGCGCG
AGAAGTTTCTGAATGCACATCGTTAGCGGATTGGATGAGTTTGGTTTTAAACGCCTCCATCGTTTTAGAA
AATTCTTGCAAGGCTTTGTCGGTATTGAGCGTTGAAGTGTAAGCGTTTTGCGCCACATCAATGCCTTGAT
CTAAGGTGTTTTCTTCGTATTGGAATTTTAAATTCTGGTTGTTAATGTCGCTGTTTTGATAACCATAACG
GATTTTTAGCCCTGAAGCGATCTGCGTGTTAGCGTCGTTGATTTTATTTTGTAAAGCGTTTTGGTAGTTA
TTCATTTGGTTGTATTTTGAGCCAAAGGTAACGCGCA
Protein Sequence 
>gi|15644923|ref|NP_207093.1| flagellar hook-associated protein FlgL [Helicobacter pylori 26695] MRVTFGSKYNQMNNYQNALQNKINDANTQIASGLKIRYGYQNSDINNQNLKFQYEENTLDQGIDVAQNAYTSTLNTDKALQEFSKTMEAFKTKLIQSANDVHSETSRAAIANDLERLKEHMINVANTSIGGEFLFGGSKVDRPPIDSNGKYHGNGEDLNVLISSDNLVPYNISGQDLFLGTDKDKHKLITTNIKLFNQNKLHPDVMDALEHSSLPEEVFIKPSDTLRELIGDNDKDPTNDPKEFFYLQGVRPDGSSFKEKFALDKAYQNQESASKVSDLLDKIAHAYGNTSQNKVVDVSLNNWGQIEIKNLTPGSENLDFHLISSDGDFDDLDALRSSGKRVTEYIKSAFVTDRSLSQVKAVPNMYNPKVLEVPSVFVTKDNVLANKNTKLSEIFGDSVETLKINASRLDETSAIKIPNLPVYLDIPILLDVKNSTIKDLKDAIKKRFNNEVDVEIETNGRLRIIDNSSKESPISLALSALDAKGLEVAGIPTNNASEYQKTYFNKEGAKLESNVAQTAQNGAANGSTKLSEAAKGSLENSVFNMKLNDVNGLFLEAQMNLDNNGAFLSLPNGIKIPLYDPTSADIQASKPNEVTYRQLMDAMSIALNYSNTDPAIYQQISDNPTSKESKERFIGLLKQAKDNLSVNLNEEGKVIIQDNMHSNTKMQFMLFDKDANDFSQNALHSDKPSLKLNANNALIIDKPSVNFFDQLENTITSVRKGIYRPDALGDTYSSDMRNLGIQNGITLIDHLSDHIEKMIAKNGAHGKAFENIIRRNEVLKTQVQSIRGETTGTDMAETYNKFSNLTNNYNAVLASTNKINNLSLTKYL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a flgL mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG1344N, under N: Cell motility
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].