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HP1206

Victor ID 347
Gene Name HP1206
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 898800
NCBI Protein GI 15645820
Locus Tag HP1206
Protein Accession NP_207998.1
Other Database IDs UniProtKB-ID: O25807_HELPY
UniRef100: UniRef100_O25807
UniRef90: UniRef90_B2UUW9
UniRef50: UniRef50_B2UUW9
UniParc: UPI00000D31A2
EMBL: AE000511
EMBL-CDS: AAD08251.1
RefSeq_NT: NC_000915.1
HSSP: P08716
GenomeReviews: AE000511_GR
KEGG: hpy:HP1206
NMPDR: fig|85962.1.peg.1194
TIGR: HP_1206
HOGENOM: HBG321321
OMA: DNETERE
ProtClustDB: CLSK872522
Taxonomy ID 85962
Gene Starting Position 1282578
Gene Ending Position 1284314
Gene Strand (Orientation) +
Protein Name multidrug resistance protein (hetA)
DNA Sequence 
>gi|15644634:1282578-1284314 Helicobacter pylori 26695, complete genome
TATGGCAAAAAAAAAACATAAAATTTCTACTTTAAAATACTTTTTGCGCTCTTTAAAGCAAATCTACATG
CTCATCACTTTCAAGGAAAAAATGGTTTTTTTCCTGCTTGTGCTGATGGCTGTTTTTTCTTCTTTTGTGG
AAGTGATGTCTCTAACTCTCCTGATGCCTTTTATCACTCTCGCTTCCGATCCTAATAGGGCTTTAGACGA
TAAAGATTGGAAAATGGTTTATGATTTTTTCCATTTTTCATCTCCCGTTCGTCTTATGTATTTCTTTAGT
TTTTGCTTGGTGGGGATTTATTTGTTCAGGATGTTTTATGGGGTGTCTTTCACTTATTTGAAAGGGCGTT
TTTCCAATAAGAAAGCCTATCAAATCAAGCAACAACTTTTTTTACAGCACATTAAAAGCAACTACCTCTC
CCACCTTAACCACAACTTGGATTCTTTAAGAGACATTATCAACAATAAAGCAGAAGGCATGTTTATGAGC
TTTAACGCATTCTTAAGCTTGCTCACTGAAATAACTGTGATCGTTTTTTTCTACTCCACGCTCATATTAA
CTAACTGGAAAATAACGCTCGTTTTTACTATGATCCTCGCCTTACAAATTTTTCTTATTGTCAAAAAAGT
CACCGTTCTCATCAAGAAAAAGGGTGAGATGGCTGCCAAATCCAAAGCGCAAACGCTTAAAGTTTTTTCA
AAATTTTTCAGCAATTTCAAAATCACTAAACTCAAAGACAACCACGAAGAAGCCCACAAGCTCTTTGGAG
AAAATAGCCGTAAAGCCCATGACACTGAGATTATTTACGCTACTTTGCAAGTAGTCCCCAGGTATTCAAT
AGAAACGGTGGGCTTTAGCTTGTTGATTTTAGCGGTCGCTTACATTCTATTCAAATACGGCGAAGCTAAA
ATGGTGCTCCCTACCATTTCTATGTATGCTCTAGCGCTTTATCGCATACTCCCTTCTGTGACTGGAATGA
TCAACTACTACAATGAAATCGCTTACAACCAGCTTGCGACCAACATGGTTTTTAAAAGCCTTTCTAAAAC
CATCGTTGAAGAGGATTTAGTCCCTTTAGACTTTAATGAAAAAATCACTCTTCAAAACATTTCATTCGCT
TATAAGTCAAAGCATCCGGTTTTGAAAGATTTTAACCTCACCATTCAAAGAGGTCAGAAAGTCGCTCTCA
TAGGCCATAGTGGGTGCGGGAAATCCACGCTAGCGGATATTATTATGGGGCTTACTTACCCTAAAAGCGG
GGAAATTTTTATTGATAACACCCTTTTAACCAACAAAAACAGGCGCTCATGGCGTAAAAAAATAGGCTAT
ATCCCCCAAAATATTTACCTTTTTGATGGCACTGTGGGGGATAATATCGCTTTTGGGAGTGCCATAGATG
AAAAACGCTTGATTAAGGTGTGCAAAATGGCTCATATTTATGATTTTTTATGCGAGCATGAAGGCCTTAA
AACCCAAGTGGGCGAAGGGGGTGCTAAGCTTAGCGGCGGTCAAAAACAGCGCATAGGCATTGCAAGAGCC
TTATACGATAACCCTGAAATTTTGGTTTTAGATGAAGCCACTTCGGCCCTAGACAACGAAACCGAGAGTA
AAATCATGGATGAAATCTATCAAATCGCTAAAAATAAAACTCTGATCGTTATCGCCCACCGCTTAAGCAC
GATTGAACGCTGTGAAGTCATCATTGACATGAGCCAACACAAAGACAATCTCGGCTA
Protein Sequence 
>gi|15645820|ref|NP_207998.1| multidrug resistance protein HetA [Helicobacter pylori 26695] MAKKKHKISTLKYFLRSLKQIYMLITFKEKMVFFLLVLMAVFSSFVEVMSLTLLMPFITLASDPNRALDDKDWKMVYDFFHFSSPVRLMYFFSFCLVGIYLFRMFYGVSFTYLKGRFSNKKAYQIKQQLFLQHIKSNYLSHLNHNLDSLRDIINNKAEGMFMSFNAFLSLLTEITVIVFFYSTLILTNWKITLVFTMILALQIFLIVKKVTVLIKKKGEMAAKSKAQTLKVFSKFFSNFKITKLKDNHEEAHKLFGENSRKAHDTEIIYATLQVVPRYSIETVGFSLLILAVAYILFKYGEAKMVLPTISMYALALYRILPSVTGMINYYNEIAYNQLATNMVFKSLSKTIVEEDLVPLDFNEKITLQNISFAYKSKHPVLKDFNLTIQRGQKVALIGHSGCGKSTLADIIMGLTYPKSGEIFIDNTLLTNKNRRSWRKKIGYIPQNIYLFDGTVGDNIAFGSAIDEKRLIKVCKMAHIYDFLCEHEGLKTQVGEGGAKLSGGQKQRIGIARALYDNPEILVLDEATSALDNETESKIMDEIYQIAKNKTLIVIAHRLSTIERCEVIIDMSQHKDNLG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP1206 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG1132V, under V: Defense mechanisms
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].