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potD from Streptococcus pneumoniae G54

Victor ID 3459
Gene Name potD from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6480374
NCBI Protein GI 194398708
Locus Tag SPG_1325
Protein Accession YP_002038032.1
Other Database IDs UniProtKB-ID: B5E5P2_STRP4
UniRef100: UniRef100_E0SUR9
UniRef90: UniRef90_C1CEX4
UniRef50: UniRef50_Q2YX72
UniParc: UPI0000051817
EMBL: CP001015
EMBL-CDS: ACF56823.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000022797.
EnsemblGenome_TRS: EBSTRT00000022797
EnsemblGenome_PRO: EBSTRP00000021963
GenomeReviews: CP001015_GR
KEGG: spx:SPG_1325
HOGENOM: HBG638705
OMA: WADYVAP
ProtClustDB: CLSK884080
Taxonomy ID 512566
Gene Starting Position 1294492
Gene Ending Position 1295562
Gene Strand (Orientation) -
Protein Name spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein
DNA Sequence 
>gi|194396645:1294492-1295562 Streptococcus pneumoniae G54 chromosome, complete genome
CCTACTTCCGATACATTTTAAACTGTAGGAAGAGGTCGCTATATTTCCCTGTCCATTTATGGTCAAATTT
CTCATAAACTTCTAGGTGTTTCATGGTTTCAACATCGGGATAGAAGGCCTTATCTTCCTTTGTTTCCTCT
GGGAGCAATTCCTTCGCTGGTAGGTTTGGTGTTGAATAGCCGACATACTCCGCATTTTGGAGAGCATTTT
CAGGTTTCAACATAAAGTTGATAAAGGCATAGGCTGAGTTTTGGTTTTTAACTGTTTTGGGAATGACCAT
ATTGTCAAACCAAAGATTGCTGGCCTCTGTCGGTACCACATAACGTAGATTTTCATTTTTTTCTAACATT
TGGCTGGCTTCACCAGAGAAGGTCACGCCGATTGCAACATTATTCTGAATCATATAGCCCTTCATCTCGT
CCGCAACGATAGCCTTGATATTTGGAGTCAGTTTGTAGAGCTTATCCACTGTCTCTTCCAACTGCTGCAG
ATCCTTGGAGTTGAGACTGTAGCCGAGGGAATTGAGTCCTAGTCCCAGCACCTCACGCGCCCCATCAAAG
AGCATGATAGAATTCTTATACTCCGGCTTCCAAAGGTCATCCCAATGCTCAGGCGCTTCATCTACCATGG
TTTCGTTGTAGACAATTCCTAAGGTTCCCCAGAAGTAAGGGATGGAGAATTTATTACCTGGGTCAAAGGA
CTGGTTGAGAAACTCTGGTCCGATATTTTCGATTCCTTCAATTTTTGAATAATCAAGCGGAACCAAGAGG
TCTTCGTCCTTCATCTTGTTAATCATGTATTCACTTGGAATGGCAATATCGTAGGTCGTTCCACCCTGCT
TTATCTTAGTGTACATGGCTTCGTTGGAGTCAAAAGTCTCGTACTGAACTTGAATTCCTGTTTCTTCTGT
AAACTGAGTCAAGAGTTCAGGATCGATATAGTCTCCCCAGTTATAGATAACCAATTTTTGACTATCTCGA
CTATTGATTTTACTATCTAAATGAGTCGCAATTCCCCACAAGACAAGGATAATCGCTGCAATTCCTGCTA
AAAATGAATAGATTTTTTTCA
Protein Sequence 
>gi|194398708|ref|YP_002038032.1| spermidine/putrescine ABC transporter spermidine/putrescine-binding protein [Streptococcus pneumoniae G54] MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGDYIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDLLVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDLWKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVADEMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNSAYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYEKFDHKWTGKYSDLFLQFKMYRK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: potD mutant is attenuated in pulmonary and systemic models of infection in mice (Ware et al., 2006).
COG COG0687E, under E: Amino acid transport and metabolism
References
Ware et al., 2006: Ware D, Jiang Y, Lin W, Swiatlo E. Involvement of potD in Streptococcus pneumoniae polyamine transport and pathogenesis. Infection and immunity. 2006; 74(1); 352-361. [PubMed: 16368990].