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lytA from Streptococcus pneumoniae G54

Victor ID 3458
Gene Name lytA from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6480363
NCBI Protein GI 194397555
Locus Tag SPG_1847
Protein Accession YP_002038529.1
Other Database IDs UniProtKB-ID: B5E2D8_STRP4
UniRef100: UniRef100_P06653
UniRef90: UniRef90_P32762
UniRef50: UniRef50_P32762
UniParc: UPI0000051A56
EMBL: CP001015
EMBL-CDS: ACF55670.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000020936.
EnsemblGenome_TRS: EBSTRT00000020936
EnsemblGenome_PRO: EBSTRP00000020102
GenomeReviews: CP001015_GR
KEGG: spx:SPG_1847
HOGENOM: HBG702446
OMA: YDIENGL
ProtClustDB: CLSK560258
Taxonomy ID 512566
Gene Starting Position 1758316
Gene Ending Position 1759272
Gene Strand (Orientation) -
Protein Name autolysin
DNA Sequence 
>gi|194396645:1758316-1759272 Streptococcus pneumoniae G54 chromosome, complete genome
ATTATTTTACTGTAATCAAGCCATCTGGCTCTACTGTGAATTCTGGCTTGTCTGCCAGTGTTCCGTCTGG
TTTGAGGTAGTACCAGCCTGTTCCGTCCGCTGACTGGATAAAGGCATTTGATACCATGGCGCCTTCTTTA
GCGTCTAAGTAGTACCAAGTGTCCTTGTACTTGACCCAGCCTGTCTTCATGGCACCTTCTTCGTTGAAAT
AGTACCACTTATCAGCGATTTTCTTCCAGCCTGTAGCCATTTCGCCTGAGTTGTCGAACCAGTACCAGTT
GCCGTCTGTGTGCTTCCTCCAGCGGTCTGCAAGCATATAGCCTGAACTGTCAAAGTAGTACCAAGTGCCA
TTGATTTTCTCAAACTTGTCTTTTGGATAAGAGCCGTCTGAATGTACGTACCAGTAGCCAGTGTCATTCT
TCTGCCAGCCTGTTTCAATCGTCAAGCCGTTCTCAATATCATGCTTAAACTGCTCACGGCTAATGCCCCA
TTTTGCCAAGTAAGGGTATGGATCCACATGGTCTGAGTGGTTGTTTGGTTGGTTATTCGTGCAATACTCG
TGCGTTTTAATTCCAGCTAAACTCCCTGTATCAAGCGTTTTCGGCAAACCTGCTTCATCTGCTAGATTGC
GTAAGAGTTCGATATAAAGGCGGTAGTCCGTCATGAACTCTTCTTTAGTTGAATGGCTTTCAATCAGTTC
AACCGCTGCATAGGTCTCAGCATTCCAACCGCCCCCAACGTCCCAGGCACCATTATCAACAGGTCCTACC
TGCATGATGCAACCGTTCCCAACAATGTGCGAGAAAAAACCTAATTCTGGGTCTTTCCGCCAGTGATAAT
CCGCTTCATTCTGTACGGTTGAATGCGGATTCCCAGTTGAGTGTGCGTGTACTTGCCTATATGGTTGCAC
GCCGACTTGAGGCAAATCTGTTCTTAATTTACTCACATTAATTTCCA
Protein Sequence 
>gi|194397555|ref|YP_002038529.1| autolysin [Streptococcus pneumoniae G54] MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGISREQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytA mutant is attenuated in mice (Berry and Paton, 2000).
COG COG5263R, under R: General function prediction only
References
Berry and Paton, 2000: Berry AM, Paton JC. Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins. Infection and immunity. 2000; 68(1); 133-140. [PubMed: 10603379].