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pspC from Streptococcus pneumoniae G54

Victor ID 3455
Gene Name pspC from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6480115
NCBI Protein GI 194398341
Locus Tag SPG_2135
Protein Accession YP_002038785.1
Other Database IDs UniProtKB-ID: B5E3T5_STRP4
UniRef100: UniRef100_B5E3T5
UniRef90: UniRef90_B5E3T5
UniRef50: UniRef50_B5E3T5
UniParc: UPI00017C1700
EMBL: CP001015
EMBL-CDS: ACF56456.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000021773.
EnsemblGenome_TRS: EBSTRT00000021773
EnsemblGenome_PRO: EBSTRP00000020939
GenomeReviews: CP001015_GR
KEGG: spx:SPG_2135
OMA: AQPGTED
Taxonomy ID 512566
Gene Starting Position 2027842
Gene Ending Position 2030151
Gene Strand (Orientation) -
Protein Name surface protein PspC
DNA Sequence 
>gi|194396645:2027842-2030151 Streptococcus pneumoniae G54 chromosome, complete genome
ATTATTTTCTTCTTTTCATCGCGATGAATGAAGTTCCAATCAAACCAAGGAGACCAATGATCTCAAGAAC
TAGATTAGACGCCACTCCTGTAGATGGCAATTTCTTCTCTGTTGCTACAGCAAGCTTAGCTTTTTCTTTC
TCCTGATTAATCTCTGGTACACTTGGTTTCTTACCCTCTGGTTGAGGGCTTGGTTGCATATCTGGTTTTG
GAGCAGATGGCTTTTTATCCTCAGTACCGGGTTGTGCCGGTACACTTGGTTTCTTGCCTTCTGGTTGAGG
ACTTGGTTGCATATCTGGTTTTGGAGCAGATGGCTTTTTATCCTCAGTACCAGGTTGTGCCGGTACGCTT
GGTTTCTTGCCTTCTGGTTGAGGACTTGGTTGCATACCTGGTTTTGGAGCAGATGGCTTTTTATCCTCAG
TACCAGGTTGTGCCGGTACGCTTGGTTTCTTGCCTTCTGGTTGAGGACTTGGTTGCATATCTGGTTTTGG
AGCAGATGGCTTTTTATCCTCAGTACCAGGTTGTGCCGGTACGCTTGGTTTCTTGCCTTCTGGTTGAGGA
CTTGGTTGCATACCTGGTTTTGGAGCAGATGGCTTTTTATCCTCAGTACCAGGTTGTGCCGGTACGCTTG
GTTTCTTGCCTTCTGGTTGAGGACTTGGTTGCATACCTGGTTTTGGAGCAGATGGCTTTTTGTTATCTGG
TTCTTTTGGTGTGTCCTGAGTTAAGCCTTTTTTGAATTTAGTCACAACTGCATCCATGTCTGCAAATATC
TTGTGGACTGTATTTTCAATTTCTACTTTGGTATTTACATTATCAATTTCAGAAAGAGCTTGCTTTTTAA
ACTCATCAAGCTCCTTAATAAGAGCAACAATCTGACGATGTTTTTCTTTCTGCAGATGATGTTTTTGTAT
ATCATCTAAAATCTTGCTCATGTAGGTTGCTACAGCAAGCTTAGCTTTTTCTTTTTCCTGATTAATATCT
GGTACGCTTGGTTTCTTACCCTCTGGTTGAGGGATTGGTTTGGTATCCGGAGCTGGAGTTGTTGGTCTTT
GATGCTCTGGATTTTCCGGCTGCGGTTTAACCTCTGGTACCAATTTCGCTTTAGCCTCTCTCAATTTAGA
CATGGCATCGTTCAATTTGGTTAATTGCATTGCCAGTTCATCCATTGTCACTGCTGTCTGTGATAGAAGT
TTCTTGTTTTCAGAAACAACTTTTATTGCATAATCTCTGACCTCATTATAGGCATTTCCAGCTTCTCCTG
TGAGTTTAGCCCCATCTGGAACAGTTTTTGTTTCACCATCTAGTTTGTTCAAGGATTCTTGAATGGCTAC
CATCTGCTGGTTTTTATTGAAAGCTGGACGGAAGTCTTTTTCAAAATAATCTTTTTTATCAGGTGTTGCT
TGCTCTCCAAGAGCTCCTCGTTTTACCCGCCTCTTTGGTTTACCTTGCTCTGAAGTCGCTGCATTCTTTT
CAACAGCTTCCTTCAACTTAGCTTCTTCTTCTGCTTTTTTACGATCTGTCTTGATTTTTTTTAACCTTGT
AGCCTCAGCTTGTTTACTCTCAACTTCCGCTTCTGCTTGCTTAATTTTTTTCTCGTCTCGAGATTCCTTA
GCTTTCACTTTTACTAGTTCAAGCTCCGCTTCTTTAACTTTCACATCGAACTCAGCAATTTCAAGTTCAA
GCGTTTTGTAAGTAATGGTTGGGTAGTTACGGTAATCTTCTTCTTTTTGATCCTTGGCTTTTTTCTCAGC
TTCTTCAACCTTCTGCTGAGCTTCTGCTACCTTTTTTTCTAGTTCTGTCGGCTTGTTTGGCTTCGCTGTA
TCTGAAGCTTCCGGTTCCGTGGAAGAGCCTGAACTTGACGAAGAAGATAAGTCCTTTTCAAATTCAGACA
CAGCTTTATCTACTTCTGATTGACTCTCCATCATCAGTTTCTGTAGTTCTTCGTATGTTGAGGTTGATTG
AATTATTTTATTCAAATACTCGTTATTAATGTTTTGCAACTTGTTAACTATATCTACAGTCTTCTTATGT
CGACTTTTAGTTGATTTTGAATAGAGCTCTTTCACTTTTTTTTCTTTATATTCCCTGACCTCTTTCTTTA
CCTTATCTCGTTCTAAATCGAGTTCTCTACGTTGTTCTGCCTGACTTTCATTTCCCCTATTAGAAGAAGT
GGGTGCTTGGGTAGTTCCCTCGTTCTCTGTCGCATGAACCACACTTCCCATAACAAGACTGGCAACAGCT
ACACTAGCTACTCCTATACTAAATTTTCGAATAGAATAGCACATTTTTCTTTCATAATTTGATTTAAACA
Protein Sequence 
>gi|194398341|ref|YP_002038785.1| surface protein PspC [Streptococcus pneumoniae G54] MFKSNYERKMCYSIRKFSIGVASVAVASLVMGSVVHATENEGTTQAPTSSNRGNESQAEQRRELDLERDKVKKEVREYKEKKVKELYSKSTKSRHKKTVDIVNKLQNINNEYLNKIIQSTSTYEELQKLMMESQSEVDKAVSEFEKDLSSSSSSGSSTEPEASDTAKPNKPTELEKKVAEAQQKVEEAEKKAKDQKEEDYRNYPTITYKTLELEIAEFDVKVKEAELELVKVKAKESRDEKKIKQAEAEVESKQAEATRLKKIKTDRKKAEEEAKLKEAVEKNAATSEQGKPKRRVKRGALGEQATPDKKDYFEKDFRPAFNKNQQMVAIQESLNKLDGETKTVPDGAKLTGEAGNAYNEVRDYAIKVVSENKKLLSQTAVTMDELAMQLTKLNDAMSKLREAKAKLVPEVKPQPENPEHQRPTTPAPDTKPIPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDEFKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPDNKKPSAPKPGMQPSPQPEGKKPSVPAQPGTEDKKPSAPKPGMQPSPQPEGKKPSVPAQPGTEDKKPSAPKPDMQPSPQPEGKKPSVPAQPGTEDKKPSAPKPGMQPSPQPEGKKPSVPAQPGTEDKKPSAPKPDMQPSPQPEGKKPSVPAQPGTEDKKPSAPKPDMQPSPQPEGKKPSVPEINQEKEKAKLAVATEKKLPSTGVASNLVLEIIGLLGLIGTSFIAMKRRK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pspC mutant has reduced ability to colonize the nasopharynx of mice compared to t he wild type (Ogunniyi et al., 2007).
References
Ogunniyi et al., 2007: Ogunniyi AD, LeMessurier KS, Graham RM, Watt JM, Briles DE, Stroeher UH, Paton JC. Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model. Infection and immunity. 2007; 75(4); 1843-1851. [PubMed: 17261599].