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luxS from Streptococcus pneumoniae G54

Victor ID 3454
Gene Name luxS from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6480079
NCBI Protein GI 194398223
Locus Tag SPG_0309
Protein Accession YP_002037024.1
Other Database IDs UniProtKB-ID: LUXS_STRP4
UniRef100: UniRef100_Q04MC2
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI00000513CE
EMBL: CP001015
EMBL-CDS: ACF56338.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000020976
EnsemblGenome_TRS: EBSTRT00000020976
EnsemblGenome_PRO: EBSTRP00000020142
GenomeReviews: CP001015_GR
KEGG: spx:SPG_0309
HOGENOM: HBG347473
OMA: VRIAKTM
ProtClustDB: PRK02260
Taxonomy ID 512566
Gene Starting Position 298881
Gene Ending Position 299363
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase
DNA Sequence 
>gi|194396645:298881-299363 Streptococcus pneumoniae G54 chromosome, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTTTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGGCAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCAGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|194398223|ref|YP_002037024.1| S-ribosylhomocysteinase [Streptococcus pneumoniae G54] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].