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ciaR from Streptococcus pneumoniae G54

Victor ID 3448
Gene Name ciaR from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6479630
NCBI Protein GI 194398608
Locus Tag SPG_0728
Protein Accession YP_002037443.1
Other Database IDs UniProtKB-ID: B5E3I0_STRP4
UniRef100: UniRef100_P0A4H8
UniRef90: UniRef90_P0A4H8
UniRef50: UniRef50_P0A4H8
UniParc: UPI0000127989
EMBL: CP001015
EMBL-CDS: ACF56723.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000022471.
EnsemblGenome_TRS: EBSTRT00000022471
EnsemblGenome_PRO: EBSTRP00000021637
GenomeReviews: CP001015_GR
KEGG: spx:SPG_0728
HOGENOM: HBG753323
OMA: VILPKEQ
ProtClustDB: CLSK876907
Taxonomy ID 512566
Gene Starting Position 706798
Gene Ending Position 707472
Gene Strand (Orientation) +
Protein Name CiaR response regulator TCS05
DNA Sequence 
>gi|194396645:706798-707472 Streptococcus pneumoniae G54 chromosome, complete genome
CATGATAAAAATCTTATTGGTTGAGGATGACCTAGGTCTGTCAAATTCAGTATTTGACTTTTTAGACGAT
TTTGCGGATGTTATGCAGGTATTTGATGGAGAAGAAGGTCTNTACGAAGCTGAGAGTGGTGTCTATGACT
TGATTTTGCTGGATTTGATGTTGCCAGAAAAAAATGGTTTCCAAGTCTTAAAAGAATTGCGTGAAAAGGG
AATTACGACACCAGTTCTGATTATGACTGCCAAGGAAAGTTTGGATGACAAGGGACATGGATTTGAACTG
GGAGCGGATGATTATCTGACCAAACCTTTCTACCTAGAAGAACTTAAAATGCGGATTCAGGCCCTTCTCA
AACGTTCAGGGAAGTTTAATGAAAACACCTTGACTTATGGGAATATCGTGGTTAATTTATCAACCAATAC
CGTTAAAGTTGAAGATACTCCTGTCGAATTGCTGGGGAAAGAGTTCGATTTACTAGTTTATTTCCTTCAA
AATCAAAATGTGATTTTGCCTAAGACGCAGATTTTTGACCGTCTATGGGGATTTGATAGTGATACAACGA
TTTCGGTTGTCGAAGTCTATGTTTCAAAAGTCCGTAAGAAATTAAAGGGAACCACTTTTGCAGAGAATTT
GCAAACCTTGCGTAGTGTTGGGTATCTTTTAAAAGATGTTCAGTA
Protein Sequence 
>gi|194398608|ref|YP_002037443.1| CiaR response regulator TCS05 [Streptococcus pneumoniae G54] MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVYFLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGYLLKDVQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ciaR mutant is attenuated in mice (Ibrahim et al., 2004).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Ibrahim et al., 2004: Ibrahim YM, Kerr AR, McCluskey J, Mitchell TJ. Control of virulence by the two-component system CiaR/H is mediated via HtrA, a major virulence factor of Streptococcus pneumoniae. Journal of bacteriology. 2004; 186(16); 5258-5266. [PubMed: 15292127].