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cpsB

Victor ID 3446
Gene Name cpsB
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6479425
NCBI Protein GI 194398654
Locus Tag SPG_0315
Protein Accession YP_002037030.1
Other Database IDs UniProtKB-ID: B5E790_STRP4
UniRef100: UniRef100_B5E790
UniRef90: UniRef90_Q54518
UniRef50: UniRef50_Q9AHD4
UniParc: UPI00017C1682
EMBL: CP001015
EMBL-CDS: ACF56769.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000022252.
EnsemblGenome_TRS: EBSTRT00000022252
EnsemblGenome_PRO: EBSTRP00000021418
GenomeReviews: CP001015_GR
KEGG: spx:SPG_0315
HOGENOM: HBG288653
OMA: CYTQVNS
ProtClustDB: CLSK883942
Taxonomy ID 512566
Gene Starting Position 305221
Gene Ending Position 305952
Gene Strand (Orientation) +
Protein Name tyrosine-protein phosphatase wzh
DNA Sequence 
>gi|194396645:305221-305952 Streptococcus pneumoniae G54 chromosome, complete genome
AATGATAGACATCCATTCGCATATCGTTTTTGATGTAGATGACGGTCCCAAGTCAAGAGAGGAAAGCAAG
GCTCTCTTGGCAGAATCCTACAGGCAGGGGGTGCGAACCATTGTCTCTACCTCTCACCGTCGCAAGGGCA
TGTTTGAAACTCCGGAAGAGAAGATAGCAGAAAACTTTNTTCAGGTTCGGGAAATTGCAAAAGAAGTGGC
AGATGATTTAGTCATTGCTTATGGCGCAGAGATATACTATACTCTGGATGCTCTAGAAAAGCTAGAAAAA
AAAGAAATTCCTACCCTTAATGATAGTCGTTATGCCTTGATTGAGTTTAGCATGCATACTTCCTATCGTC
AGATTCATACGGGATTGAGCAATATTTTGATGTTGGGAATCACGCCAGTAATTGCTCATATTGAACGTTA
TGATGCTTTAGAGAATAACGAAAAACGTGTTCGTGAACTGATTGATATGGGGTGCTATACTCAGATAAAT
AGTTATCATGTTTCAAAACCTAAGTTCTTTGGTGAAAAATATAAATTCATGAAAAAGAGAGCTCGGTATT
TTTTGGAACGTGATTTAGTTCATGTAGTTGCAAGTGACATGCACAATTTAGACAGTAGACCTCCATATAT
GCAACAGGCATATGATATCATTGCTAAGAAATATGGAGCGAAAAAAGCAAAAGAACTTTTTGTAGATAAT
CCCAGAAAAATTATAATGGATCAATTAATTTA
Protein Sequence 
>gi|194398654|ref|YP_002037030.1| tyrosine-protein phosphatase wzh [Streptococcus pneumoniae G54] MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRRKGMFETPEEKIAENFXQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDSRYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYTQINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIAKKYGAKKAKELFVDNPRKIIMDQLI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cpsB mutant is avirulent in mice (Morona et al., 2004).
COG COG4464GM, under G: Carbohydrate transport and metabolism; M: Cell wall/membrane/envelope biogenesis
References
Morona et al., 2004: Morona JK, Miller DC, Morona R, Paton JC. The effect that mutations in the conserved capsular polysaccharide biosynthesis genes cpsA, cpsB, and cpsD have on virulence of Streptococcus pneumoniae. The Journal of infectious diseases. 2004; 189(10); 1905-1913. [PubMed: 15122528].