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pgdA from Streptococcus pneumoniae G54

Victor ID 3445
Gene Name pgdA from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6479325
NCBI Protein GI 194397649
Locus Tag SPG_1406
Protein Accession YP_002038113.1
Other Database IDs UniProtKB-ID: B5E646_STRP4
UniRef100: UniRef100_B5E646
UniRef90: UniRef90_Q04JM3
UniRef50: UniRef50_Q04JM3
UniParc: UPI00017C1728
EMBL: CP001015
EMBL-CDS: ACF55764.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000021282.
EnsemblGenome_TRS: EBSTRT00000021282
EnsemblGenome_PRO: EBSTRP00000020448
GenomeReviews: CP001015_GR
KEGG: spx:SPG_1406
HOGENOM: HBG703418
OMA: AHELYYS
ProtClustDB: CLSK884105
Taxonomy ID 512566
Gene Starting Position 1361079
Gene Ending Position 1362416
Gene Strand (Orientation) -
Protein Name peptidoglycan GlcNAc deacetylase (pgdA)
DNA Sequence 
>gi|194396645:1361079-1362416 Streptococcus pneumoniae G54 chromosome, complete genome
CTTATTCATCACGACTATAATACAGCTCATGAGCTTTTAGGCGAGTATTGAGCATCTCTGGTATGGTCAC
AAAGGTATAACCTTGATTTTTCAAATACTCAATGANCCTTGGCAAGGCATTGACTGTCGGACTGTGAATA
TCATGCATCAAAANGATAGAGCCGTTAGCTACTTGATGNTGAATTTNTGTCAAAATAGATGCTTNATTTT
TACTCTTCCAGTCCAGACTATCCACATCCCACATGATAAAGCTCAAATCCAAGCTATTGCGAATATCATC
TGTAATAGCACCATAAGGTGGACGCATGAGTTTAGAACTAGAACCCAGCACTTTAGTTAGCACATCCTCA
GTATCAGTAATCTGCTTTTTAGCTTCATCAAGAGAGAGTTGCGAGAGAATCGGATGGCTCCAACTATGGT
TTCCAACAACATGACCTTCAGATTTTATCCTCTTCACCAAGTCCTCATTCCCAGAAACATTTTTCCCAAG
CACAAAGAAAGTCGCTTTAATATCATATTTAGCTAGGGTCTCTAATACCTGCGGGGTCGTTGCTGGATTT
GGACCATCATCAAAGGTTAGAGCGACAACTTTTTGATGTTTCTTATCAAAGTAAGATTGGTACAAGGCCG
CATCTTTTTCGAGTAAGTACGAAGATTGGATAACATCAAAGAAAGCAGATACTGGCAAGGCTATCTCTTC
TAAATTTTCAACCACAGGACTTGGATAAAGGATAATCTGACTATCCTTGTAATCAAAATTCCATGCAGAC
AAGTCTTGGTCAGAGAAGTTTTTTACAATCTGCTCACTCTGGTCTTGCTCTATTTTTTTATCCTCTATGA
AGGAGGTCAACTCTTTTATCAGCTGTTCCTTAGCCTTACTAGCATCTGAAAACAGTTGGTCAAGTGTAAA
AGGTTGCCCATCTTCTGTTAAGTGAACCTTTCCTAGACTGGTCTTTTCAGTCTCTTCAATCTTAAAAGCA
ACTAAATCATAGATTTGTTTGGTCACATTACGATTAACGACTCCCTTTAAACCTGACTCTTCTTGCTCTG
TATAGTAGAAAACAAGATTGTCCTTACTTTCTAGCTTGTCCTTAACATCTTGATTTATCAGCTCCCTAAC
AGAGGAAATCACTTTCTCCCCTTGGAGAGGATAATAGGCAATCACTTCGGCTTGCCCCTGACGAAAATGC
TCCTTCTGATTTCCCTCACTCAATTGATCATCTTTCTCTTTTTTGAGCGATTCAATCTTTTGCTCAAAAC
TTTTTTGCTGGTAGATCTTAAAAGCAATAAATCCGCCTAATAGGCAAATAGAAATTGCTAAAATACCAAT
CAAAGCCA
Protein Sequence 
>gi|194397649|ref|YP_002038113.1| peptidoglycan GlcNAc deacetylase PgdA [Streptococcus pneumoniae G54] MALIGILAISICLLGGFIAFKIYQQKSFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKDKLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDDGPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILSQLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDWKSKNXASILTXIXHQVANGSIXLMHDIHSPTVNALPRXIEYLKNQGYTFVTIPEMLNTRLKAHELYYSRDE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pgdA mutant is attenuated in mice (Vollmer and Tomasz, 2002).
COG COG0726G, under G: Carbohydrate transport and metabolism
References
Vollmer and Tomasz, 2002: Vollmer W, Tomasz A. Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae. Infection and immunity. 2002; 70(12); 7176-7178. [PubMed: 12438406].