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lytB from Streptococcus pneumoniae G54

Victor ID 3440
Gene Name lytB from Streptococcus pneumoniae G54
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6479000
NCBI Protein GI 194398062
Locus Tag SPG_0889
Protein Accession YP_002037600.1
Other Database IDs UniProtKB-ID: B5E484_STRP4
UniRef100: UniRef100_B5E484
UniRef90: UniRef90_P59206
UniRef50: UniRef50_P59206
UniParc: UPI00017C1903
EMBL: CP001015
EMBL-CDS: ACF56177.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000021092.
EnsemblGenome_TRS: EBSTRT00000021092
EnsemblGenome_PRO: EBSTRP00000020258
GenomeReviews: CP001015_GR
KEGG: spx:SPG_0889
HOGENOM: HBG702253
OMA: YYFKSGG
ProtClustDB: CLSK559969
Taxonomy ID 512566
Gene Starting Position 857205
Gene Ending Position 859313
Gene Strand (Orientation) +
Protein Name endo-beta-N-acetylglucosaminidase
DNA Sequence 
>gi|194396645:857205-859313 Streptococcus pneumoniae G54 chromosome, complete genome
AATGAAGAAAGTAAGATTTATTTTTTTAGCTCTGCTATTTTTCTTAGCTAGTCCAGAGGGTGCAATGGCT
AGTGATGGTACTTGGCAAGGAAAACAGTATCTGAAAGAAGATGGCAGTCAAGCAGCGAATGAGTGGATTT
TTGATACTCATTATCAATCTTGGTTCTATATAAAAGCAGATGCTAACTATGCTGAAAATGAATGGCTAAA
GCAAGGTGACGACTATTTTTACCTCAAATCTGGTGGCTATATGGCCAAATCAGAATGGGTAGAAGACAAG
GGAGCCTTTTATTATCTTGACCAAGATGGAAAGATGAAAAGAAATGCTTGGGTAGGAACTTCCTATGTTG
GTGCAACAGGTGCCAAAGTAATAGAAGACTGGATCTATGATTCTCAATACGATGCTTGGTTTTATATCAA
AGCAGATGGACAGCACGCAGAGAAAGAATGGCTCCAAATTAAAGGGAAGGACTATTATTTCAAATCCGGT
GGTTATCTACTGACAAGTCAGTGGATTAATCAAGCTTATGTGAATGCTAGTGGTGCCAAAGTACAGCAAG
GTTGGCTTTTTGACAAACAATACCAATCTTGGTTTTACATCAAAGAAAATGGAAACTATGCTGATAAAGA
ATGGATTTTCGAGAATGGTCACTATTATTATCTAAAATCCGGTGGCTACATGGCAGCCAATGAATGGATT
TGGGATAAGGAATCTTGGTTTTATCTCAAATTTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATT
CTCATAGTCAAGCTTGGTACTACTTCAAATCCGGTGGCTACATGGCAGCCAATGAATGGATTTGGGATAA
GGAATCTTGGTTTTACCTCAAGTTTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGT
CAAGCCTGGTACTACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTT
GGTTTTATCTCAAATCTGATGGGAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTG
GTACTACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTAC
CTCAAGTCTGATGGCAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCCTGGTACTACT
TCAAATCTGGTGGCTACATGGCGAAAAATGAGACAGTAGATGGTTATCAGCTTGGAAGCGATGGTAAATG
GCTTGGAGGAAAAGCTACAAATAAAAATGCTGCTTACTATCAAGTAGTGCCTGTCACAGCCAATGTTTAT
GATTCAGATGGTGAAAAGCTTTCCTATATATCGCAAGGTAGTGTCGTATGGCTAGATAAGGATAGAAAAA
GTGATGACAAGCGCTTGGCTATTACTATTTCTGGTTTGTCAGGCTATATGAAAACAGAAGATTTACAAGC
GCTAGATGCTAGTAAGGACTTTATCCCTTATTATGAGAGTGATGGCCACCGTTTTTATCACTATGTGGCT
CAGAATGCTAGTATCCCAGTAGCTTCTCATCTTTCTGATATGGAAGTAGGCAAGAAATATTATTCGGCAG
ATGGCCTGTATTTTGATGGTTTTAAGCTTGAGAATCCCTTCCTTTTCAAAGATTTAACAGAGGCTACAAA
CTACAGTGCTGAAGAATTGGATAAGGTATTTAGTTTGCTAAACATTAATAATAGCCTTTTGGAGAACAAG
GGCGCTACTTTTAAGGAAGCCGAAGAACATTACCATATCAATGCCCTTTATCTCCTTGCCCATAGTGCCC
TAGAAAGTAACTGGGGAAGAAGTAAAATTGCCAAAGATAAGAATAATTTCTTTGGCATTACAGCCTATGA
TACGACCCCTTACCTTTCTGCCAAGACATTTGATGATGTGGATAAGGGAATTTTAGGTGCAACCAAGTGG
ATTAAGGAAAATTATATCGATAGGGGAAGAACTTTCCTTGGAAACAAGGCTTCTGGTATGAATGTGGAAT
ATGCTTCAGACCCTTATTGGGGCGAAAAAATTGCTAGTGTGATGATGAAAATCAATGAGAAGNTAGGTGG
CAAAGATTA
Protein Sequence 
>gi|194398062|ref|YP_002037600.1| endo-beta-N-acetylglucosaminidase [Streptococcus pneumoniae G54] MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWIFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWIYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLYFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKXGGKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lytB has reduced colonization of nasopharynx of rats compared to the wild type (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].