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cbpE from S treptococcus pneumoniae G54

Victor ID 3438
Gene Name cbpE from S treptococcus pneumoniae G54
Sequence Strain (Species/Organism) S treptococcus pneumoniae G54
NCBI Gene ID 6478968
NCBI Protein GI 194397033
Locus Tag SPG_0856
Protein Accession YP_002037567.1
Other Database IDs UniProtKB-ID: B5E432_STRP4
UniRef100: UniRef100_B5E432
UniRef90: UniRef90_B8ZP33
UniRef50: UniRef50_D3H8I6
UniParc: UPI00017C18C4
EMBL: CP001015
EMBL-CDS: ACF55148.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000022770.
EnsemblGenome_TRS: EBSTRT00000022770
EnsemblGenome_PRO: EBSTRP00000021936
GenomeReviews: CP001015_GR
KEGG: spx:SPG_0856
HOGENOM: HBG702245
OMA: HYYLEES
ProtClustDB: CLSK559958
Taxonomy ID 512566
Gene Starting Position 831518
Gene Ending Position 833401
Gene Strand (Orientation) +
Protein Name choline binding protein E
DNA Sequence 
>gi|194396645:831518-833401 Streptococcus pneumoniae G54 chromosome, complete genome
AATGAAAAAGAAATTAACTAGTTTAGCACTTGTAGGCGCTTTTTTAGGTTTGTCATGGTATGGGAATGTT
CAGGCTCAAGAAAGTTCAGGAAATAAAATCCACTTTATCAATGTTCAAGAAGGTGGCAGTGATGCGATTA
TTCTTGAAAGCAATGGACATTTTGCCATGGTGGATACAGGAGAAGATTATGACTTCCCAGACGGTAGTGA
TTCTCGCTATCCATGGAGAGAAGGAATTGAAACGTCTTATAAGCATGTTCTAACAGACCGTGTCTTTCGT
CGTTTGAAGGAATTGGGTGTCCAAAAACTTGATTTTATTTTGGTGACCCATACCCACAGTGATCATATTG
GAAATGTTGATGAATTACTGTCTACCTATCCAGTTGACCGAGTCTATCTTAAGAAATATAGTGATAGTCG
TATTACTAATTCTGAACGTCTATGGGATAATCTGTATGGCTATGATAAGGTTTTACAGACTGCTGCAGAA
AAAGGTGTTTCAGTTATTCAAAATATCACACAAGGGGATGCTCATTTTCAGTTTGGGGACATGGATATTC
AGCTCTATAATTATGAAAATGAAACTGATTCATCGGGTGAATTAAAGAAAATTTGGGATGACAATTCCAA
TTCCTTGATTAGCGTGGTGAAAGTCAATGGCAAGAAAATTTACCTTGGGGGCGATTTAGATAATGTTCAT
GGAGCAGAAGACAAGTATGGTCCTCTCATTGGAAAAGTTGATTTGATGAAGTTTAATCATCACCATGATA
CCAACAAATCAAATACCAAGGATTTCATTAAAAATTTGAGTCCGAGTTTGATTGTTCAAACTTCGGATAG
TCTACCTTGGAAAAATGGTGTTGATAGTGAGTATGTTAATTGGCTCAAAGAACGAGGAATTGAGAGAATC
AACGCAGCCAGCAAAGACTATGATGCAACAGTTTTTGATATTCGAAAAGACGGTTTTGTCAATATTTCAA
CATCCTACAAGCCTATTCCAAGTTTTCAAGCTGGTTGGCATAAGAGTTCATATGGAAACTGGTGGTATCA
AGCGCCTGATTCTACAGGAGAGTATGTTGTCGGTTGGAATGAAATTAAGGGTGAATGGTATTACTTTAAC
CAAACGGGTATCTTATTACAGAATCAATGGAAAAAATGGAACAATCGTTGGTTCTATTTGACAGACTCTG
GTGTTGCTGCTAAAAATTGGAAGAAAATCGCTGGAATCTGGTATTATTTTAACAAAGAAAACCAGATGGA
AATTGGTTGGATTCAAGATAAAGAGCAGTGGTATTATTTGGATGTTGATGGCTCTATGAAGACAGGTTGG
CTTCAATATAAGGGGCAATGGTATTACTTTGCTCCATCAGGGGAAATGAAAACGGGCTGGGTAAAAGATA
AAGAAGCCTGGTACTATATGGATTCTACTGGTATCATGAAGACAGGTGAGATAGAAGTTGCTGGACATCA
TTACTATCTAGAAGAATCAGGAGCTATGAAGCAAGGCTGGCTTAAAAAGGCAAATGATTGGTATTTCTAC
AAGACAGATGGTTCACGAGCTATAGGTTGGATTAAAGACAAGGATAAATGGTACTTCTTGAAAGAAAATG
GTCAATTACTTGTGAATGGTAAGACACCAGAAGGCTATACTGTGGATTCAAGTGGTGCCTGGTTAGTGGA
TGTTCCGATCGAGAAATCTGCTACAATTAAAACTACAAGTCATTCAGAAATAAAAGAATCCAAAGAAGTA
GTGAAAAAGGATCTTGAAAATAAAGAAACGAGTCAACATGAAAGTGTTACAAATTCTTCAACTAGTCAAG
ATTTGACATCCTCAACTTCACAAAGCTCTGAAACGAGTGTAAACAAATCGGAATCAGAACAGTA
Protein Sequence 
>gi|194397033|ref|YP_002037567.1| choline binding protein E [Streptococcus pneumoniae G54] MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSDAIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQKLDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQTAAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKVNGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPSFQAGWHKSSYGNWWYQAPDSTGEYVVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKANDWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSESEQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cbpE has reduced colonization of nasopharynx of rats and reduced adherence to human epithelial cells (Gosink et al., 2000).
COG COG5263R, under R: General function prediction only
References
Gosink et al., 2000: Gosink KK, Mann ER, Guglielmo C, Tuomanen EI, Masure HR. Role of novel choline binding proteins in virulence of Streptococcus pneumoniae. Infection and immunity. 2000; 68(10); 5690-5695. [PubMed: 10992472].