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cpsC

Victor ID 3436
Gene Name cpsC
Sequence Strain (Species/Organism) Streptococcus pneumoniae G54
NCBI Gene ID 6478888
NCBI Protein GI 194396683
Locus Tag SPG_0316
Protein Accession YP_002037031.1
Other Database IDs UniProtKB-ID: B5E791_STRP4
UniRef100: UniRef100_B5E791
UniRef90: UniRef90_Q54519
UniRef50: UniRef50_Q97SJ6
UniParc: UPI00017C1683
EMBL: CP001015
EMBL-CDS: ACF54798.1
RefSeq_NT: NC_011072.1
EnsemblGenome: EBSTRG00000021153.
EnsemblGenome_TRS: EBSTRT00000021153
EnsemblGenome_PRO: EBSTRP00000020319
GenomeReviews: CP001015_GR
KEGG: spx:SPG_0316
HOGENOM: HBG697325
OMA: YTSTTRI
ProtClustDB: CLSK883943
Taxonomy ID 512566
Gene Starting Position 305961
Gene Ending Position 306653
Gene Strand (Orientation) +
Protein Name capsular polysaccharide biosynthesis protein wzh
DNA Sequence 
>gi|194396645:305961-306653 Streptococcus pneumoniae G54 chromosome, complete genome
TATGAAGGAACAAAACACTTTGGAAATCGATGTATTGCAACTATTCAGAGCTTTATGGAAAAGAAAGTTG
GTCATTTTATTAGTGGCAATTATAACTTCTTCAGTTGCTTTTGCCTACAGTACTTTTGTTATCAAACCTG
AGTTTACTAGTATGACTCGGATTTATGTAGTTAACCGTGATCAGGGAGAGAAGTCTGGTTTAACCAATCA
AGACTTGCAGGCAGGATCATCCTTGGTTAAAGACTATCGTGAAATTATCCTATCGCAGGATGTTTTGGAG
GAAGTTGTTTCTGATTTGAAACTAGATTTGACGCCAAAAGATTTGGCTAATAAAATTAAAGTAACAGTAC
CAGTTGATACCCGTATTGTCTCTGTTTCAGTTAGTGATCGAGTTCCTGAAGAGGCAAGCCGTATCGCTAA
CTCTTTGAGAGAAGTAGCTGCTCAAAAAATTATCAGTATTACTCGTGTTTCTGATGTGACAACACTGGAG
GAGGCAAGACCGGCGACATCACCGTCTTCGCCAAATATTAAACGCAGTACACTAATTGGTTTTTTGGCAG
GAGTGATTGGAACTAGTGTTATAGTTCTTATTCTTGAACTTTTGGACACTCGTGTGAAACGTCCGAAAGA
TATCGAAGATACACTGCAGATGACACTTTTGGGAATTNTACCAAACTTGAATAAGTTGAAATA
Protein Sequence 
>gi|194396683|ref|YP_002037031.1| capsular polysaccharide biosynthesis protein Wzh [Streptococcus pneumoniae G54] MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVIKPEFTSMTRIYVVNRDQGEKSGLTNQDLQAGSSLVKDYREIILSQDVLEEVVSDLKLDLTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVTTLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLQMTLLGIXPNLNKLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cpsC mutant is avirulent in mice (Morona et al., 2004).
COG COG3944M, under M: Cell wall/membrane/envelope biogenesis
References
Morona et al., 2004: Morona JK, Miller DC, Morona R, Paton JC. The effect that mutations in the conserved capsular polysaccharide biosynthesis genes cpsA, cpsB, and cpsD have on virulence of Streptococcus pneumoniae. The Journal of infectious diseases. 2004; 189(10); 1905-1913. [PubMed: 15122528].