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napA

Victor ID 3387
Gene Name napA
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 7010614
NCBI Protein GI 210134443
Locus Tag HPP12_0243
Protein Accession YP_002300882.1
Other Database IDs UniProtKB-ID: B6JKH4_HELP2
UniRef100: UniRef100_E1Q270
UniRef90: UniRef90_Q9ZMJ1
UniRef50: UniRef50_Q9ZMJ1
UniParc: UPI00000B8C79
EMBL: CP001217
EMBL-CDS: ACJ07402.1
RefSeq_NT: NC_011498.1
GenomeReviews: CP001217_GR
KEGG: hpp:HPP12_0243
HOGENOM: HBG672882
ProtClustDB: CLSK872309
Taxonomy ID 570508
Gene Starting Position 249322
Gene Ending Position 249756
Gene Strand (Orientation) -
Protein Name neutrophil-activating protein A
DNA Sequence 
>gi|210134201:249322-249756 Helicobacter pylori P12 chromosome, complete genome
CTTAAGCCAAATGGGCTTCTAGCATCCAAATGGATTTTTGCAACTTGGCCAATTGATCGTCCGCATAAGT
TACGGTAACTTTATCGCCTTCTTTTTCAGCGGTGTTAGAAAGCTCTTTAAATTCTTTTTCTAGGTGTTTG
TAATCGCCTAGAATTTCTTTAAAGATGTCTTTAGAGTGGAAGCTCGTTTTAGTTTCTTCTTTAACACGAG
TGAGTTTGAGTGCTTCGCTTAAAGTGACTAAGGGGTGGTGTCCTAATTGAGCGATCCTTTCAGCGAGATC
ATCAAACATGTCCGCAAACTCTTCATAAATTTCTTCAGTGGCTTTATGCACATTGAAAAAATCGGTGCCT
TTCACATTCCAATGGAAGTTATGCACTTTCATAAATAACACGATCGCATCCGCTTGCAAATGTTTTAAAA
TTTCAAATGTTTTCA
Protein Sequence 
>gi|210134443|ref|YP_002300882.1| neutrophil-activating protein A [Helicobacter pylori P12] MKTFEILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIAQLGHHPLVTLSEALKLTRVKEETKTSFHSKDIFKEILGDYKHLEKEFKELSNTAEKEGDKVTVTYADDQLAKLQKSIWMLEAHLA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion impaired adherence to host cells (Petersson et al., 2006).
COG COG0783P, under P: Inorganic ion transport and metabolism
References
Petersson et al., 2006: Petersson C, Forsberg M, Aspholm M, Olfat FO, Forslund T, Borén T, Magnusson KE. Helicobacter pylori SabA adhesin evokes a strong inflammatory response in human neutrophils which is down-regulated by the neutrophil-activating protein. Medical microbiology and immunology. 2006; 195(4); 195-206. [PubMed: 16758245].