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dppA from Escherichia coli O157:H7 str. EC 4115

Victor ID 3371
Gene Name dppA from Escherichia coli O157:H7 str. EC 4115
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EC 4115
NCBI Gene ID 6967851
NCBI Protein GI 209396782
Locus Tag ECH74115_4912
Protein Accession YP_002273027.1
Other Database IDs UniProtKB-ID: B5YVJ4_ECO5E
UniRef100: UniRef100_C3SNC2
UniRef90: UniRef90_P23847
UniRef50: UniRef50_P23847
UniParc: UPI000000E731
EMBL: CP001164
EMBL-CDS: ACI35615.1
RefSeq_NT: NC_011353.1
EnsemblGenome: EBESCG00000031552.
EnsemblGenome_TRS: EBESCT00000032502
EnsemblGenome_PRO: EBESCP00000031205
GenomeReviews: CP001164_GR
KEGG: ecf:ECH74115_4912
HOGENOM: HBG688042
OMA: TVELWAM
ProtClustDB: CLSK880713
Taxonomy ID 444450
Gene Starting Position 4551191
Gene Ending Position 4552798
Gene Strand (Orientation) -
Protein Name dipeptide ABC transporter, periplasmic dipeptide-binding protein
DNA Sequence 
>gi|209395693:4551191-4552798 Escherichia coli O157:H7 str. EC4115, complete genome
ATTATTCGATAGAGACGTTTTCGAAGTGATGTTTGCCTAATGGATCAACCACATAGCCTTTAACTTCTTT
GCGTACCGGTTCAAACACGGTGGAGTGAGCGATGATCAGTGCCGGAGCCTGATCGTGCATCACCACCTGC
GCTTGCTTGTACAGTTCAACGCGTTTGTTATGGTCGTCGGTAGCACGCGCCGGTTGAATCAGATCTTCAA
ACGGTTTGTAGCACCATTTTGAGTAGTTGGAGCCTTGTTCAGAGGCGGCGCAGCTGAACAGAGTGGCGAA
GAAGTTATCCGGATCCCCGTTATCGCCAGTCCAGCCCATCATTACCGTCTGGTGCTCGCCATCTTTCGCA
CGCTTGAGGTACTCACCCCATTCGTAGGTGACAATTTTGGCCTGCACGCCGACTTTCGCCCAGTCTGCCT
GAATCATCTCCGCCATGCGGCGAGCGTTCGGGTTATACGGACGTTGTACCGGCATCGCCCACAGGTCGAT
GGAGAAACCTTTTTCCAGACCCGCTTCTTTCAGCAAGGCTTTCGCTTTTTCAGGATCGTAGGTGTAGTCC
TGAACGTCGTCGTTATAGCCCCACATGGTTGGCGGGATCAGGTTTTTCGCTGATACACCCGCGCCCTGAT
AAACCGCTTTGATGATCGCGTCTTTGTTCACCGCGTAGGTCAGAGCCTGGCGAACTTTCACGTCATCGAG
TGGTTTTTTCTGCACGTTATACGAGAGATAACCGACGTTCAGCCCCGGCATTTCCATCAGGTTGATAGAT
TTATCCTGCTTCATGCGGGCGATATCTGCCGGGTTCGGGTACGGCATCACCTGGCATTCATTTTTCTGCA
ATTTAGCGTAACGCACGGAAGCGTCAGGGGTAATAGAGAAAACCAGCGTATCGATCTGCGGTTTGGTGCC
CCAGTAGCCATCAAACGCTTTGTAGCGGATACGGGAATCTTTTTGATACTGCTGTAACTGGAACGGACCG
GTGCCGATTGGGTTGAGGTCCAGTTTTTCCGGTGTACCGGCTTTCATCATCGCATCAGCATATTCTTTTG
ACAGAATAGAGGCGAAGTCCATTGCCAGGTCAGCGAGGAACGGCGCTTCCGGGCGAGTCAGCACAAACTG
AACGGTGTTGTCGTCCACCTTTTTCACTTCGCTGATCAGCTCCGGCAAGCCCATGCCTTCGAAGTATTCG
TAGCTGCCGCCAGAAACTTTATGGTACGGGTTTTGCGCGTTTTTCTGACGATCGAACGAGAACACCACGT
CATCGGCATTCATTTCGCGCGTCGGTTTGAATTCTTTATTGTCGTGCCACTTCACACCTTTACGCAGATG
GAAGGTATAGGTTTTACCGTCTTCGCTGACTTCCCACTTTTCAGCGAGGCCCGGAATCACTTCGGTGGTG
CCGATTTTAAATTCAACTAGGCGGTTATAAAGCGGTACGGAAGAGGCGTCATAGGTGGTACCGGAGGTAA
ACAGCTGCGGGTTAAACCCTTCCGGAGATCCTTCTGAGCAATAAACCAGAGTTTTAGCCTGAACACTTGC
TGCGACGGTCATAGCCACCAGGCTGAGACCAAGCTTCAGCATCCCTGACTTTTTCAAGGAAATACGCA
Protein Sequence 
>gi|209396782|ref|YP_002273027.1| dipeptide ABC transporter substrate-binding protein [Escherichia coli O157:H7 str. EC4115] MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTREMNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dppA mutant was attenuated 10- to 50-fold compared to the wild type for colonization of the bladders and kidneys of mice (Haugen et al., 2007).
COG COG0747E, under E: Amino acid transport and metabolism
References
Haugen et al., 2007: Haugen BJ, Pellett S, Redford P, Hamilton HL, Roesch PL, Welch RA. In vivo gene expression analysis identifies genes required for enhanced colonization of the mouse urinary tract by uropathogenic Escherichia coli strain CFT073 dsdA. Infection and immunity. 2007; 75(1); 278-289. [PubMed: 17074858].