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dsbA from Escherichia coli O157:H7 str. EC 4115

Victor ID 3370
Gene Name dsbA from Escherichia coli O157:H7 str. EC 4115
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. EC 4115
NCBI Gene ID 6967123
NCBI Protein GI 209400816
Locus Tag ECH74115_5300
Protein Accession YP_002273372.1
Other Database IDs UniProtKB-ID: B5YYZ2_ECO5E
UniRef100: UniRef100_P0AEG5
UniRef90: UniRef90_P0A4L6
UniRef50: UniRef50_P0A4L6
UniParc: UPI000002D10B
EMBL: CP001164
EMBL-CDS: ACI39649.1
RefSeq_NT: NC_011353.1
EnsemblGenome: EBESCG00000032220.
EnsemblGenome_TRS: EBESCT00000033170
EnsemblGenome_PRO: EBESCP00000031873
GenomeReviews: CP001164_GR
KEGG: ecf:ECH74115_5300
HOGENOM: HBG680642
OMA: PAMYVNG
ProtClustDB: PRK10954
Taxonomy ID 444450
Gene Starting Position 4942484
Gene Ending Position 4943110
Gene Strand (Orientation) +
Protein Name periplasmic protein disulfide isomerase I
DNA Sequence 
>gi|209395693:4942484-4943110 Escherichia coli O157:H7 str. EC4115, complete genome
CATGAAAAAGATTTGGCTGGCGCTGGCTGGTTTAGTTTTAGCGTTTAGCGCATCGGCGGCGCAGTATGAA
GATGGTAAACAGTACACTACCCTGGAAAAACCGGTAGCTGGCGCGCCGCAAGTGCTGGAGTTTTTCTCTT
TCTTCTGCCCGCACTGCTATCAGTTTGAAGAAGTTCTGCATATTTCTGATAATGTGAAGAAAAAACTGCC
GGAAGGCGTGAAGATGACTAAATACCACGTCAACTTCATGGGTGGTGACCTGGGCAAAGATCTGACTCAG
GCATGGGCTGTGGCGATGGCGCTGGGCGTGGAAGACAAAGTGACTGTTCCGCTGTTTGAAGGCGTACAGA
AAACCCAGACCATTCGTTCAGCATCTGATATCCGCGATGTATTTATCAACGCAGGTATTAAAGGTGAAGA
GTACGACGCGGCGTGGAACAGCTTCGTGGTGAAATCTCTGGTCGCTCAGCAGGAAAAAGCTGCAGCTGAC
GTGCAATTGCGTGGTGTTCCGGCGATGTTTGTTAACGGTAAATATCAGCTGAATCCGCAGGGTATGGATA
CCAGCAATATGGATGTTTTTGTTCAGCAGTATGCTGATACAGTGAAATATCTGTCCGAGAAAAAATA
Protein Sequence 
>gi|209400816|ref|YP_002273372.1| protein disulfide isomerase I [Escherichia coli O157:H7 str. EC4115] MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutation of dsbA led to degradation of bundilin and an absence of localized adherence to host cells in EPEC (Donnenberg et al., 1997).
COG COG1651O, under O: Posttranslational modification, protein turnover, chaperones
References
Donnenberg et al., 1997: Donnenberg MS, Zhang HZ, Stone KD. Biogenesis of the bundle-forming pilus of enteropathogenic Escherichia coli: reconstitution of fimbriae in recombinant E. coli and role of DsbA in pilin stability--a review. Gene. 1997; 192(1); 33-38. [PubMed: 9224871].