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pCP8533etx_p28

Victor ID 3367
Gene Name pCP8533etx_p28
Sequence Strain (Species/Organism) Clostridium perfringens
NCBI Gene ID 7003474
NCBI Protein GI 209947607
Locus Tag pCP8533etx_p28
Genbank Accession M80837
Protein Accession YP_002291114
Other Database IDs UniProtKB-ID: Q57398_CLOPE
UniRef100: UniRef100_B1R956
UniRef90: UniRef90_Q02307
UniRef50: UniRef50_Q02307
UniParc: UPI00000BA812
EMBL: M80837
EMBL: AY858558
EMBL: AB444205
EMBL: X60694
EMBL-CDS: AAA23235.1
EMBL-CDS: AAW47580.1
EMBL-CDS: BAG75487.1
EMBL-CDS: CAA43104.1
RefSeq_NT: NC_011412.1
PDB: 1UYJ
ProtClustDB: CLSK2480728
Taxonomy ID 1502
Plasmid No pCP8533etx
Gene Starting Position 28144
Gene Ending Position 29130
Gene Strand (Orientation) +
Protein Name epsilon toxin
Protein pI 9.13
Protein Weight 33145.19
Protein Length 328
Protein Note PCP8533E-27
DNA Sequence 
>gi|209947580:28144-29130 Clostridium perfringens plasmid pCP8533etx, complete sequence
TATGAAAAAAAATCTTGTAAAAAGTTTAGCAATCGCATCAGCGGTGATATCCATCTATTCAATAGTTAAT
ATTGTTTCACCAACTAATGTAATAGCTAAGGAAATATCTAATACAGTATCTAATGAAATGTCCAAAAAAG
CTTCTTATGATAATGTAGATACATTAATTGAGAAAGGAAGATATAATACAAAATATAATTACTTAAAGAG
AATGGAAAAATATTATCCTAATGCTATGGCATATTTTGATAAGGTTACTATAAATCCACAAGGAAATGAT
TTTTATATTAATAATCCTAAAGTTGAATTAGATGGAGAACCATCAATGAATTATCTTGAAGATGTTTATG
TTGGAAAAGCTCTCTTAACTAATGATACTCAACAAGAACAAAAATTAAAATCACAATCATTCACTTGTAA
AAATACTGATACAGTAACTGCAACTACTACTCATACTGTGGGAACTTCGATACAAGCAACTGCTAAGTTT
ACTGTTCCTTTTAATGAAACAGGAGTATCATTAACTACTAGTTATAGTTTTGCAAATACAAATACAAATA
CTAATTCAAAAGAAATTACTCATAATGTCCCTTCACAAGATATACTAGTACCAGCTAATACTACTGTAGA
AGTAATAGCATATTTAAAAAAAGTTAATGTTAAAGGAAATGTAAAGTTAGTAGGACAAGTAAGTGGAAGT
GAATGGGGAGAGATACCTAGTTATTTAGCTTTTCCTAGGGATGGTTATAAATTTAGTTTATCAGATACAG
TAAATAAGAGTGATTTAAATGAAGATGGTACTATTAATATTAATGGAAAAGGAAATTATAGTGCAGTTAT
GGGAGATGAGTTAATAGTTAAGGTTAGAAATTTAAATACAAATAATGTACAAGAATATGTAATACCTGTA
GATAAAAAAGAAAAAAGTAATGATTCAAATATAGTAAAATATAGGAGTCTTTCTATTAAGGCACCAGGAA
TAAAATA
Protein Sequence 
>gi|209947607|ref|YP_002291114.1| epsilon toxin [Clostridium perfringens]
MKKNLVKSLAIASAVISIYSIVNIVSPTNVIAKEISNTVSNEMSKKASYDNVDTLIEKGRYNTKYNYLKR
MEKYYPNAMAYFDKVTINPQGNDFYINNPKVELDGEPSMNYLEDVYVGKALLTNDTQQEQKLKSQSFTCK
NTDTVTATTTHTVGTSIQATAKFTVPFNETGVSLTTSYSFANTNTNTNSKEITHNVPSQDILVPANTTVE
VIAYLKKVNVKGNVKLVGQVSGSEWGEIPSYLAFPRDGYKFSLSDTVNKSDLNEDGTININGKGNYSAVM
GDELIVKVRNLNTNNVQEYVIPVDKKEKSNDSNIVKYRSLSIKAPGIK
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: epsilon-toxin interacts with vascular endothelial cells and increases the vessel wall permeability by direct damage of the endothelium (Adamson et al., 2005).
References
Adamson et al., 2005: Adamson RH, Ly JC, Fernandez-Miyakawa M, Ochi S, Sakurai J, Uzal F, Curry FE. Clostridium perfringens epsilon-toxin increases permeability of single perfused microvessels of rat mesentery. Infection and immunity. 2005; 73(8); 4879-4887. [PubMed: 16041001].