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SP_2022

Victor ID 3361
Gene Name SP_2022
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 932024
NCBI Protein GI 15901843
Locus Tag SP_2022
Protein Accession NP_346447.1
Other Database IDs UniProtKB-ID: Q97NK4_STRPN
UniRef100: UniRef100_Q97NK4
UniRef90: UniRef90_E0SY76
UniRef50: UniRef50_A4W8F9
UniParc: UPI0000051AB0
EMBL: AE005672
EMBL-CDS: AAK76087.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000027187.
EnsemblGenome_TRS: EBSTRT00000027187
EnsemblGenome_PRO: EBSTRP00000026279
GenomeReviews: AE005672_GR
KEGG: spn:SP_2022
TIGR: SP_2022
HOGENOM: HBG532931
OMA: QTPWTTP
ProtClustDB: CLSK803897
BioCyc: SPNE170187-1:SP_2022-MONOMER
Taxonomy ID 170187
Gene Starting Position 1927875
Gene Ending Position 1929170
Gene Strand (Orientation) +
Protein Name PTS system, IIC component
DNA Sequence 
>gi|194172857:1927875-1929170 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGAAAAACTCAAAATTTATAGACCAATTTGCCACCTTTGCTGGTAAACTAGGGAACCAAATTCATTTA
AAAACCCTAAGAGATGCATTCGTAACAGTAATGCCATTATATATTTTGGCAGGTTTAATCGTTCTTTTGA
ACAACACGGTATTTAAGTGGATTTTCCAAGGGGATACATTAACAAGATTCCAATATTGGGGAATAACAAT
TGCAAACGGTACTTTAAGTATTTCAGGTATGATTATTGCTGTAATGGTTGGTTATTTCTTAGCTAAAAAC
AGAGATTTCGAAAACCCGTTAGCAGCATCAATGCTATCATTAGTTTCTTTAATTGTGATGATGCCAAATA
CAGTTTCTGTAGTTCCTGACGGAGCAAAAGATGCGGTAAACATTTCAGGTGTTCTTTCATTCAACAACAC
AGGTACAGGCGCAATGTTCGCCGGGGTTATCGTAGCGATTATTGCAACAGAATTATTCATTGAATTATCA
AACGTTAAAGCTTTACAAATGAACCTTGGTGAAAATATTCCACCAGCTGTTAGTAGATCATTTAGCGTAT
TACTTCCAGTCATGACCGTCATCTCCTTATTTGGGGTTGTTTCAGCATTATTATTCAATATAACTGGAAT
GAACTTAATCTCAATCATTACAATCTTTATTCAAGAACCAATTCGTCATATTGGTACAAGCTTAATCGGG
GTCATTATTATTTACTCTTTAGGAAATATGTTATGGCTATTTGGTATTCACCAAGCAGTTATTTACAGTG
CCATCCTAGAACCATTACTATTAATTAACATTACTGAAAACATCACTGCAGCAAATAATGGACAAGCCAT
TCCACACATCATCAACCTATCACAAATACAAACATTCGCTTTAATGGGTGGTAGTGGATCTACATTATGT
TTATTAATAGCAACATTCTTAGTGAGTCGCAATGCTGTCTCTAAAAACGTGGCTAAATTATCTTTTGGAC
CTGGTATCTTCAATATCAATGAACCAGTATTATTCGGTTACCCAATCGTTTATAACATTTCATTAGCTAT
TCCATTTATCACAGTTCCAGTCCTTGGTATTTTAATCAGCTACTTAGCAACAGTTACAGAATTCATGAGT
CCTGCATTTATACAAGTTCCTTGGACTACACCAGTATTCTTAAATGCATGGTTAGCAACAGCAGGGGACG
TGAGAGCAGTTCTAGTTCAATTCATCATCTTTGCACTTGGAGTTCTTCTATACATTCCATTTATCAAAGT
TAATGACAAAGTTGTTGAACAAGAAATGGAAGGTTA
Protein Sequence 
>gi|15901843|ref|NP_346447.1| PTS system transporter subunit IIC [Streptococcus pneumoniae TIGR4] MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIVLLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAASMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFIELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITIFIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANNGQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINEPVLFGYPIVYNISLAIPFITVPVLGILISYLATVTEFMSPAFIQVPWTTPVFLNAWLATAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2022 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1455G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].