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SP_2052

Victor ID 3357
Gene Name SP_2052
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931979
NCBI Protein GI 15901872
Locus Tag SP_2052
Protein Accession NP_346476.1
Other Database IDs UniProtKB-ID: O85194_STRPN
UniRef100: UniRef100_Q04IB9
UniRef90: UniRef90_E0SYH9
UniRef50: UniRef50_D3H6J9
UniParc: UPI00000D469B
EMBL: AF052207
EMBL: AE005672
EMBL-CDS: AAC23738.1
EMBL-CDS: AAK76116.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026630.
EnsemblGenome_TRS: EBSTRT00000026630
EnsemblGenome_PRO: EBSTRP00000025722
GenomeReviews: AE005672_GR
KEGG: spn:SP_2052
TIGR: SP_2052
HOGENOM: HBG517073
OMA: LITILEM
ProtClustDB: CLSK2391257
BioCyc: SPNE170187-1:SP_2052-MONOMER
Taxonomy ID 170187
Gene Starting Position 1952670
Gene Ending Position 1953542
Gene Strand (Orientation) -
Protein Name competence protein CglB
DNA Sequence 
>gi|194172857:1952670-1953542 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTAAAAATTTACCTCCATATTTTGATACATGGGCATGAGCATTGCCGCATAAAGTAAAACGATAATCAG
TGCCACAAAGATAAAAACCAGTGGCTGCACCAAATTCATGGTGCGGTTGACTCGGGTAAAAAAGGCTTCC
CAAGTTTTTTCAGCATAGATTTCCAACTCACTACCCAGCTTGGACTTAACTTCCCCATACTCTATGATGA
GACTCAATTCCTTCCTAAAGAAAGGATAGGTTCCTATCGTCTGAGAAAATTCACGGCCATTTTTCAGGGT
TTGAGCCAGATCTTGACCGACTTCTTTAAAGAGCTGGGAACCTTGTTCCTGCATCATTTGAAAAATCTGC
GTCAACTCCATTCCCTGTGAAATCATATTCCCCCATTCACGTGCATAATAGGCTGTCAAGTAGGTCTGCA
CAAAGATTCCAATAAAGGGAAGGCGTGCTAAGATAGAAAAGACACTCATCTTAGAACTTCTTTTATAAAA
AGTGAGTGCTAAAAGGGCAAGCACGGAAACAAGCCCTACCATGCCTAGAAAAATTTGGGGCAGATTACCG
ATAATTTGGGTGGCAATATTGCTACTATCCAGTTGTGGGAGCAGGTAATTCCGTAGCCCCAGCATAATTA
AGAGAAGAAAACCCAGCAAAATCAAGGGATAGGTCGCTACTTCAATCAATTTTTTCTTGACCTTAGCCAG
ATTGTCCAGATATTCTTCTATCTTTCCCAAACTCAGGTGGAGATTGCCATGAACTTCAGCTAGGGATAAC
TGAGTGACAATAGCACTTGAACATCCCAAACTTTCCATCATTTCTGAGAATGATTTCCCCTGAGACAAGC
CCACACGCATCTGGGTCACACACTGCTTGTCCA
Protein Sequence 
>gi|15901872|ref|NP_346476.1| competence protein CglB [Streptococcus pneumoniae TIGR4] MDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIFLGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEVGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNMEVNF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CglB mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1459NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].