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SP_2060

Victor ID 3356
Gene Name SP_2060
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931978
NCBI Protein GI 15901880
Locus Tag SP_2060
Protein Accession NP_346484.1
Other Database IDs UniProtKB-ID: PCP2_STRPN
UniRef100: UniRef100_Q97NG9
UniRef90: UniRef90_Q97NG9
UniRef50: UniRef50_O87765
UniParc: UPI0000051AD7
EMBL: AE005672
EMBL-CDS: AAK76124.1
RefSeq_NT: NC_003028.3
MEROPS: C15.001
EnsemblGenome: EBSTRG00000025246
EnsemblGenome_TRS: EBSTRT00000025246
EnsemblGenome_PRO: EBSTRP00000024338
GenomeReviews: AE005672_GR
KEGG: spn:SP_2060
TIGR: SP_2060
HOGENOM: HBG360405
OMA: LERCATN
ProtClustDB: PRK13197
BioCyc: SPNE170187-1:SP_2060-MONOMER
Taxonomy ID 170187
Gene Starting Position 1961764
Gene Ending Position 1962408
Gene Strand (Orientation) -
Protein Name pyrrolidone-carboxylate peptidase
DNA Sequence 
>gi|194172857:1961764-1962408 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATCAATGAGTTTCTCCGCCTACCAACTTGAGTTCCTGATCTCCATGTTCTATTATAGCGCCGATTGCTGC
TTCTATCCCTCGCCGAATATCCACTAAACTCATAGCTGGAGTAGTCGGTCTGTTCACCACCTGTTCCATC
ATATAAGGAATATGCATAAAACCTGCCTTAACATATGGAGATTTCTTTTCTACCAAATAGAGAGCCTGAT
ACATCAAATGGCTGCAGACAAAAGTCCCTGCCGTATTGGAAACAGAGGCCGGTAAGCCCTCTTTTTTTAT
AGCTTGAACCATCGCTTTAATCGGCAAACTACTAAAGTAGGCCGAAGCACCATCTGGGCGAATGGGACGG
TCAATCGGTTGATTATCTTCGTTATCAGAAATGCATGCATCGTCTTGATTAATGGTCACTCGTTCAGGTG
TCAAACTAGTTCTTCCACCAGCTTGCCCAATACAAAGGACAAAGTCAGGTTGATAACGATTCATCTCTTC
TTCCAATACTTGAGCAGATTTGTGAAAAACTGTCGGCACCTCTAGCCAACGGACCTCAGCACCATGGATT
TCAGCTGGTAAACCTTTAATGGCCTCCAAAGCTGGATTGCCCTTTTCCCCTCCAAAGGGCTCAAAACCTG
TCACTAATACTTTCA
Protein Sequence 
>gi|15901880|ref|NP_346484.1| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae TIGR4] MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPIRPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVKAGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2060 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2039O, under O: Posttranslational modification, protein turnover, chaperones
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].