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SP_2136

Victor ID 3352
Gene Name SP_2136
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931946
NCBI Protein GI 15901950
Locus Tag SP_2136
Protein Accession NP_346554.1
Other Database IDs UniProtKB-ID: Q97NB5_STRPN
UniRef100: UniRef100_Q97NB5
UniRef90: UniRef90_Q04I35
UniRef50: UniRef50_Q8DN38
UniParc: UPI0000051B2E
EMBL: AE005672
EMBL-CDS: AAK76194.1
RefSeq_NT: NC_003028.3
HSSP: P06653
EnsemblGenome: EBSTRG00000025390.
EnsemblGenome_TRS: EBSTRT00000025390
EnsemblGenome_PRO: EBSTRP00000024482
GenomeReviews: AE005672_GR
KEGG: spn:SP_2136
TIGR: SP_2136
HOGENOM: HBG702114
OMA: NGLPKFL
ProtClustDB: CLSK560332
BioCyc: SPNE170187-1:SP_2136-MONOMER
Taxonomy ID 170187
Gene Starting Position 2046655
Gene Ending Position 2048520
Gene Strand (Orientation) -
Protein Name choline binding protein PcpA
DNA Sequence 
>gi|194172857:2046655-2048520 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CCTATCCTACCCACTCACCGTTAGCATTGACTCGATAGCCATCGGGTGTAGTCGTGTTTACTAATAAATC
TCCTGAATTATAGGTATAGTACCATTTACCAGAAACTGTAACCCAACCAGTAGCCATTGAACCTGATTCA
TTTAAGTAATACCATAAGCCTTTGTCTTTAACCCAACCAGTAGCCATTGAACCTGATTCATTTAAGTAGT
ACCATAAGCCTTTGTCTTTAACCCAACCAGTAGCCATTGAACCTGATTCGTTTAAGTAATACCATAAGCC
TTTGTCTTTAACCCAACCAGTAGCCATTGAACCTGATTCATTTAAGTAGTACCATAAGCCTTTGTCTTTA
ACCCAACCAGTAGCCATTGAACCTGATTCGTTTAAGTAATACCATAAACCTTTGTCTTTAACCCAACCAG
TAGCCATTGAACCTGATTCGTTTAAGTAATACCATAAACCTTTGTCTTTAACCCAACCAACTACTCCCTG
ATTAGAATTCTTTTTAGGTTTAGCTACATCAGTTTCTTGTTTTATATTATCTACTTTTTCAACAATGATA
TCATTACTAGTAGATAAATTTGATTTAAGAACATCTTTTATATGTTCTGATGTTACATAGAACTTAACAG
TTTCAGGAATTGCAAATGTATCTTTTTTCACAGAAAACTCTGTACTTTTATTCTTAATATGAATTTCCTT
TAATGAATCTAAGACGCCACTTAGGAAGAAGGACGGCAATGAGTTGATATTATTACCAATTGTTAAACTT
TTTAATTTTGGTAAACCGTTCATAACGTGTTTACCAAAATTTTTAACATTATCTGGTAATATAAGTTCTT
TTAATTCTAAATTACCGTAAAAGGCTAAACGTTCAATAGTTTCTAAACTATTTGGTAAGCTAATTTCTTC
AAGTTTAATCGCATCTGCAAATGCAAAAGTACCGATTTTTTCTAAACCTTCATTCAATTCGAGTTTTTTC
AAGTAAGAATTTTTATTAAACGAATATGATGCAAGTTCTTTTGTCTCCTTAGGCGTTTTATAACTTTCGT
CATTTTTTTGACTTGGATAATAAATTAATTGGGTTTTATCTTTTGAAAACAAAACACCATCAACTGAGGC
AAACGATTCATTTCCTTCTTCAACATCAACATGTTTTAAGCTAGTAGTGAGTCTAAATAGATTACTTCCT
AATGTTTTAACCGATTTTGGTAATGTTAGTTTCTCTAAATTTGATAAATTAGCAAAAGCCTCATGTGATA
TTAATTCTAATTTTGAACTTGAGGAAAAGGTTAGCTTTTTCAATTTTTGACTAAAAGAAAATGCACTTGT
TCCAATATATTCTAGAGATGCAGGCAATTCAATCTCTTCTAATTCAGAAAAATCAAAAGCTCTATCTTCA
ATTTTCTCCAGCTGACTGCCTTTGTCAAAAATAATAGTTTTAGCTTTACTTCCATGGAAGCCTTTTTTTT
GTATTTTTTTTATGCTTGATGGGATAGTAATAGAGCTAGGATAGTAGACAATTCTACCTGTTTCATCTGG
ATAATAACTAAAAGCTTGACTAGCTACTTCAGTAACGGTAAATACTTTATCACCTACTGTGATTTTTGTA
GGAATCGTGAATGGTTTTCCATCTTGACCAGCTTCAAACTCTACAGGAGTAACTCCATTACCCACTTGAA
CAGTTCCTATGTTACCTTCTACAGTTAGAACCTTATATTTGATATTATTTTGTTGAATAATACTTCCAAC
TTTAGTCTCTTTGATTACTTCCGAACTAGGAGTATCTGCTAGGATTGGTTCATTAGGGACATATGCTGCT
AAAATAACCGCAGCTGTAGTTAATGATAATATTGTAGTTTTTTTCA
Protein Sequence 
>gi|15901950|ref|NP_346554.1| choline binding protein PcpA [Streptococcus pneumoniae TIGR4] MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: PcpA mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG5263R, under R: General function prediction only
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].