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SP_2142

Victor ID 3351
Gene Name SP_2142
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931944
NCBI Protein GI 15901955
Locus Tag SP_2142
Protein Accession NP_346559.1
Other Database IDs UniProtKB-ID: Q97NB0_STRPN
UniRef100: UniRef100_Q97NB0
UniRef90: UniRef90_D6ZNT8
UniRef50: UniRef50_A4VXP5
UniParc: UPI0000051B36
EMBL: AE005672
EMBL-CDS: AAK76199.1
RefSeq_NT: NC_003028.3
PDB: 2GUP
EnsemblGenome: EBSTRG00000025277.
EnsemblGenome_TRS: EBSTRT00000025277
EnsemblGenome_PRO: EBSTRP00000024369
GenomeReviews: AE005672_GR
KEGG: spn:SP_2142
TIGR: SP_2142
HOGENOM: HBG730260
OMA: YGALVNW
ProtClustDB: CLSK884209
BioCyc: SPNE170187-1:SP_2142-MONOMER
Taxonomy ID 170187
Gene Starting Position 2052445
Gene Ending Position 2053314
Gene Strand (Orientation) -
Protein Name ROK family protein
DNA Sequence 
>gi|194172857:2052445-2053314 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CTTACCATTGCTTTTCCTCCTGTAGCCAGTTGACAAGAGCACCGTAGAGATTGGCATCTGCGTGATAGGT
GCAGGCCTGGATAACTGGTGCGACCGTGTATTCTTCGTAGGCATCGACAAAGTCTTCAACAGCCTTCTTG
ACACCTTGGATAAAATCTGGATTTTGACTGATAGAGCCACCCAGACTGATGACACCTGGATCGATCAGAT
ACTGGATATTGAGCAAGCCTTGCGCCAGATTGCGGTTCATGCGCTCAATGGCTTCTTGACAAAGGATATT
ACCAGCTGCGGCCTCTTGGTAAATCTTGCGACCGTCCCAATCAGTATGACCAGATTTTTCAATCACGTAT
CGTACCATATTCCCAGTTGATGCTAGTTGCGACCAGTTATTAAGTTTTTCAGCAGGGGCAAGGGTTGTCA
TGTAGCCAAATTCTCCACCCAGACCGTGGCGACCTCGATGAAGTCTACCATTGATAATCATGGCTCCGCC
AATCCCTGTCCCAATCACGACACAGGCTGCATTTTCAAGCTCTGGATGAGCTAGTAGTTCACTGAGTCCA
ACGCAGTTGGCATCATTTTCTAAATGGACAGGTAGCTGATAAGAGCTAAGCGCCTCATACCAAGAAAAGC
CATGGATGTAGGGCACCGCACTGAAGCCATCAATCACACCTGTCTCTTGATTGACTGCACCTGGAACGCT
CATAGCAATCCCACTGTAATCCTGTTCTGACAAGCGTTGATCTAGCCACGCTAGTAAATCCTCCAAGTTT
TCAGGCGTTGAAATACTTGTCTTATCCAGTATTTTCCCATCAGGAGTCAGACTGGCAAACTTAATCCCAG
TCCCTCCGATATCAATCGTTGCAATGGTCA
Protein Sequence 
>gi|15901955|ref|NP_346559.1| ROK family protein [Streptococcus pneumoniae TIGR4] MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLDQRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDANCVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKLNNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLNIQYLIDPGVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLYGALVNWLQEEKQW
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2142 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1940KG, under K: Transcription; G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].