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SP_2146

Victor ID 3350
Gene Name SP_2146
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931940
NCBI Protein GI 15901959
Locus Tag SP_2146
Protein Accession NP_346563.1
Other Database IDs UniProtKB-ID: Q97NA6_STRPN
UniRef100: UniRef100_D9N9Y1
UniRef90: UniRef90_C1CNC0
UniRef50: UniRef50_D3HBK5
UniParc: UPI0000051B3A
EMBL: AE005672
EMBL-CDS: AAK76203.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000027159.
EnsemblGenome_TRS: EBSTRT00000027159
EnsemblGenome_PRO: EBSTRP00000026251
GenomeReviews: AE005672_GR
KEGG: spn:SP_2146
TIGR: SP_2146
HOGENOM: HBG697253
OMA: DGFVLYP
ProtClustDB: CLSK884210
BioCyc: SPNE170187-1:SP_2146-MONOMER
Taxonomy ID 170187
Gene Starting Position 2059709
Gene Ending Position 2061388
Gene Strand (Orientation) -
Protein Name hypothetical protein
DNA Sequence 
>gi|194172857:2059709-2061388 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTATGAAACTTGGACTTGAAGTTGATCCACAAGCTGACCATCCACCGTTAGGTTCAGATAGAAATCCAA
GGTTTTATCTCCTGCGAAATACAAGGTTGGTAGCGTCAGACTTTTTTCAGTCTCACCAGTTTGAAACGCA
AGGACTTGAATCTCATCCTGATAGGCGACACCATGGACACCTGTCCCCGGTTGAATCGAAATCTTAGCTT
CTAAAGGACCACTACATTCTCTGCGCTTAACTGTAAAATAGGCATTTTCTCCCTTTGCCACAGCTAGGCT
TTTTTCTGCAAATGCTAGTTCCTGAACAACTTCTTTTTTTGATAATCCAGGAGTTTTATAAAGGGAAATC
TTGGTCAACAAAGGCAAAGCCTGTGATTCTGTAATGACTACACGTATCTTCTGTGCCTCAACAACTGCTC
CTCGTAAGAGACGTTTGTAACCAACAGTATGACCCGAACCAAACTCCTGCCAGACACCATCCACCTCTAC
TTGCACATGAAAAGCAGCGATTCGTTGCCCTAGCTTCAAATCTTCTCTTAACTCAATTACATCAAAAGTT
TTAGGAGAACCTAAGTCGAGTTCTAACTGGATGGGCAAGTCTGCATCGCTTGCCCAAGAGCTGGTCTCAA
GGCCGTCTGTCAAATGGCGACAAGCAAAGTCTGCGGAAAGAGCTGGACCAGATACCTCAGCTCCCAGAGC
CAAATCTTCTTTATAGAGCTCATTGCGATAGGTCGCAAATTCATAAAGTCGTTCAATATCCTTTGCATCA
AAGAGCCCAGCTTGATTCGGCGGAATATTAAGCAAGAGTGGAGTTCCTCGCCCTACTGAGTGAAAGTAGA
TTTCGACCAACTCCTCGAGAGACTTAGGATCCTGATCCTCATGGTAGAACCAGCCTGGACGGATGGAAAC
ATCTGCCTCTCCGATTGAAAAAATCGTGCCCGAGGGATCCCCGTGCTGAAGATAGTTCAGCTCTGCTTCT
GTTCCTAGTTTATCAGGATTCACCTTTTGCCACAGTGGATCACCTGCATACCCTCGTTCATTGCCAATCC
AGCGGATACTGGTGCCTTCTGTTGAAAAAATCAAGCAATCGCCCTGCAGGTCACGAATGGTTTCAAACCA
TTTTTCAAATTCATAATTAACCTTTTGCGCGCCCTCTCCTCTGGCACCATCCATCCAAACCTCAGCGAAC
TTACCAGCATTCCCATAGTTAGGATTTGATAAGATTTCCTTCAACTGAGCCAGATAATAGGCATTGTAGT
CCGCTTCTCGGTCCACATGATAGAGGGGACTATGGGCATCCCACGGTGACAGGTAGACCCCCATATCCAT
ATCAAACTCTGTGGCAGCTTGGGATACTTCAAGGAGCAAGTCGCCCTTTCCTCTCCTCCAAGGACTGACC
TTAACCGAATAATCTGTGTGAGCTGTCGGATAAAGGACAAAGCCATCGTGGTGCTTGACCACCAAAATCA
ACTTTTTGAAGCCCGTTTCCTTGAGCACACGAACCCACTCACGCGCATCCAACTGACTCGGGTTAAAGCG
CTCAGGATCCTCCTGTCCAGTCCCCCATTCTTGGTCATAAAAGGTATTAGGACCGAAGTGGATAAAAGCT
GCTAGTTCATCTCCCAGATAAGCTAGCTGAGTCTGACTTGGTAACGGTCCATGCGGTTTGATTTTCTTCA
Protein Sequence 
>gi|15901959|ref|NP_346563.1| hypothetical protein SP_2146 [Streptococcus pneumoniae TIGR4] MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTPGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQDEIQVLAFQTGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2146 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG3669G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].