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SP_2167

Victor ID 3348
Gene Name SP_2167
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931931
NCBI Protein GI 15901977
Locus Tag SP_2167
Protein Accession NP_346581.1
Other Database IDs UniProtKB-ID: Q97N88_STRPN
UniRef100: UniRef100_Q97N88
UniRef90: UniRef90_B2INI6
UniRef50: UniRef50_D6ZNW4
UniParc: UPI0000051B52
EMBL: AE005672
EMBL-CDS: AAK76221.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026947.
EnsemblGenome_TRS: EBSTRT00000026947
EnsemblGenome_PRO: EBSTRP00000026039
GenomeReviews: AE005672_GR
KEGG: spn:SP_2167
TIGR: SP_2167
HOGENOM: HBG313195
OMA: FGLIDNE
ProtClustDB: CLSK560345
BioCyc: SPNE170187-1:SP_2167-MONOMER
Taxonomy ID 170187
Gene Starting Position 2083304
Gene Ending Position 2084707
Gene Strand (Orientation) -
Protein Name L-fuculose kinase fucK, putative
DNA Sequence 
>gi|194172857:2083304-2084707 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTTAATTCTTTTGGGAGTAATAACTCTCTAATTGTAGAAACTCCTCAATAACATGGTGAGCCTCTTCCAT
CCCTTTTAATTGTCCCATAGCTATGAGCTGCACAACAATATTCCCCACAGCTGTAGCCTCAGTCAAACCT
GTAAGAACCTCTTTACCAGTTCTATCAGCAATCATTTGGTTAAAGTAACTGGCTCTAGCACCTCCTCCAA
TCACATATATCCTCTTATAAACCTTATGAGTTAGTTCTTCTAGTAACTCTATCGCTTTCCTATACGTTTC
AGCTAGGCTTTCATAAACAATCTTAAATAGTTGTCCATCTGTCCACTCTCTAGTTTCATGATGATAAGCT
AGATATTCTGTCAAAGTCTTGTGCATATCAGATTCTGTTGCAAATTCAGTTGATTCAGTATCAATCAGAG
GAAGATTTTCTTTTTCTTTCTCCACCATTGTCCTAATATCATCAAAAGAATAGGCTTTCCCTCTTCGTTC
AAATGAACGTCTTAGTTCCTCTATGATCCACAACCCTGTACAATTCTTCAGAAATGTAATCACTCCATCT
TTACCGACTTCATTTGTAAATCCATAACTGAAGGATTCGGTAGTAAGAATCGGTGAAGTAAGTTCCACTC
CAACCAAAGACCAAGTACCTGATGAAATAAATAAACTACCTTCTGTCTTAGGTACTGAGACAATCGCGCT
TGCTGTATCATGACTACAAACATTCACAACAGGAATATCGCCTAAACCATACTCCTCTTTTATCCTTCCA
AGAACATTTCCCTCTGAAACAATTTCAGGAAGTAAAGATGAATCCAATTCAAATAGTTTTAAGATATTCT
GATTCCAATTTTGACTCCTAGGATCAAATAATTGAGTTGTTGAAGCAATGCTTTTTTCTGTAGCAAACTT
ACCTGTCAAGAGATAATTAAACAAATCTGGCATTAAAAGAATCTTATTGGTCTTATAGAAAGAGTCAGGA
GATTCTTGACGTGCCTTAAAGAGTTGAAACAAGGTATTTATCTCCATAATCTGATTTCCTGTCTCTGAAT
ACAGTTTTTCTAATTCAGTCATTTCAGATATTTCCTTTAACACTCCCTTTGTTCTTTCATCACGATAATG
AACAGGTTGTAATAACAGCTTACCTTCATTATCAATCAGTCCAAAATCAACTCCCCATGTGTCAATACCG
ATAGATAAAATCTTGTAACTAGTATTAGCCAAGCGGATACTTTCAAGAATTTTAGCTAGTAGAAAGTCAA
TATCCCAAGATAAATGCCCTTTTACTCTAATAGGTAGATTAGAAAAGCGATTTATTTCTTCCATTACTAG
TTTATTTTCAGAAAGGTAACCAACGATTGCTCTTCCAGAAGTCGCACCTAAATCTATTGCTAAAACCGCT
TCCA
Protein Sequence 
>gi|15901977|ref|NP_346581.1| L-fuculose kinase fucK [Streptococcus pneumoniae TIGR4] MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGHLSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERTKGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFNYLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEEYGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGFTNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTESTEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKVYKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAHHVIEEFLQLESYYSQKN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fucK mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1070G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].