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SP_2236

Victor ID 3342
Gene Name SP_2236
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931908
NCBI Protein GI 15902039
Locus Tag SP_2236
Protein Accession NP_346643.1
Other Database IDs UniProtKB-ID: Q9S1K4_STRPN
UniRef100: UniRef100_B1S2X6
UniRef90: UniRef90_B5E464
UniRef50: UniRef50_B5E464
UniParc: UPI0000051B93
EMBL: AE005672
EMBL: AJ005925
EMBL-CDS: AAK76283.1
EMBL-CDS: CAB54562.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026967.
EnsemblGenome_TRS: EBSTRT00000026967
EnsemblGenome_PRO: EBSTRP00000026059
GenomeReviews: AE005672_GR
KEGG: spn:SP_2236
TIGR: SP_2236
HOGENOM: HBG697360
OMA: INDHELD
ProtClustDB: CLSK884227
BioCyc: SPNE170187-1:SP_2236-MONOMER
Taxonomy ID 170187
Gene Starting Position 2156413
Gene Ending Position 2157738
Gene Strand (Orientation) -
Protein Name putative sensor histidine kinase ComD
DNA Sequence 
>gi|194172857:2156413-2157738 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTCATTCAAATTCCCTCTTAAATCTAATGATTTGTCTAAATGTACTGCCTTCCATCTCTGTTTCTAAAAT
AATATTGTTGTACTTATCTAGTAGTTCTTTCACATTATTTAATCCGACTCCGCGATTTCTTCCCTTAGTG
GAGAATCCTAAGGCAAATAGATCTCCTGAAGGAGTCATCGTCATTTTACATGAATTCTGAATCACAATAA
CTGTTTCAGTTTCCATCTTAATAACTGCTACTTCCATCTGCTTTTTATAGCTATCAGCCGATCCTTCGAC
AGCATTATTCAATAAAACGCTCATGATACGAACCAAATCCAATAGTTCAATTGGAAGCTTGGTAATCGTA
TCTTTTACTTCCAGTGTAAACTCTACACCATTATTTCGAGCATAGACAATTGACTGAGCAACCAAACTTC
GTAAAGCTGAGTCTTCTATGTTGTTCAAATCAAAGTAAGTGTACTTATCTGAACGCAATTTATGATTTGC
TTTGACTAAAACTTCATTGTAAATTCTGTCAATTTCCTGTAAATTACCACTGTCAATTGCCATCTGCATG
CTGACAAGCATTCCAGCATAATCATGTCGAAAACCACGGATTTCATTATACAGACCAACAATTTCATCTG
TGTAATTCTGTAAATGTTTCTGTTCAAATTTCTTCTGCTTCAAAGCAATCTCTTTCTCCATTTGAACTTT
ATGAGAATTCATTGCAAAGAAGGTCAAAAGGAGAGAGATAAAGACAATAGATGACAAAATACTTCCAAAA
CTATTCAAATGTTTAATCGTACTTACCATATCTGAAACGAAAGATACAATATGTAGCAATAGTAAAGCAA
AAAATACTTTTTTCAAGAAAGGATAAAGGTAGTCCTTGTCAAAATAGGCTAGTTCCAAATGGAAATAGTA
AATGATTTTTAATGTAACAAAATAGGTTAACACCGTCACAACGAAAAAGAATGGGAAATGATATTGTAAA
ACAAAATTATCTCCTGTTATAGAGGAGAAAATTACGGACAGAAAGTTATGAGTGCTCTCATATAAAAGAG
ATAGTAGTAAACTTAGGAATAGTCCTCTATCCCTCTCATACTGTTTCATCCATCGAAAATAGGAATATAA
GCCCAAAGGAAATAAAAATCTTTCAATCCCTATTTTATCTAAATATAGAAGATAAAAGGAAAATTCAAGT
ACTATTTCAGTTAGTAATGTATAAGCACCAAAAACGTATAATTCTTTTCTATTTATTCGACCTTTACAAA
TTAAACGGTAACTGTGACTAATAATTAAAAAATGAACAATAACTGTCCCAAATCCAAGTAAATCCA
Protein Sequence 
>gi|15902039|ref|NP_346643.1| sensor histidine kinase ComD [Streptococcus pneumoniae TIGR4] MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTEIVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNFLSVIFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKKVFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIALKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_2236 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2972T, under T: Signal transduction mechanisms
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].