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SP_1998

Victor ID 3340
Gene Name SP_1998
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931895
NCBI Protein GI 15901821
Locus Tag SP_1998
Protein Accession NP_346425.1
Other Database IDs UniProtKB-ID: Q97NM2_STRPN
UniRef100: UniRef100_E0TPE3
UniRef90: UniRef90_E0TPE3
UniRef50: UniRef50_A6QH27
UniParc: UPI0000051A95
EMBL: AE005672
EMBL-CDS: AAK76065.1
RefSeq_NT: NC_003028.3
HSSP: P00805
EnsemblGenome: EBSTRG00000027002.
EnsemblGenome_TRS: EBSTRT00000027002
EnsemblGenome_PRO: EBSTRP00000026094
GenomeReviews: AE005672_GR
KEGG: spn:SP_1998
TIGR: SP_1998
HOGENOM: HBG497495
OMA: TNVATFR
ProtClustDB: CLSK877261
BioCyc: SPNE170187-1:SP_1998-MONOMER
Taxonomy ID 170187
Gene Starting Position 1900695
Gene Ending Position 1901657
Gene Strand (Orientation) +
Protein Name L-asparaginase, putative
DNA Sequence 
>gi|194172857:1900695-1901657 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CATGCCTAAGAAAATCCTTGTTTTACATACGGGTGGAACTATTTCCATGCAGGCCGATGCTTCTGGCGCT
GTTGTGACGAGTTCAGATAATCCCATGAACCATGTGTCCAACCCACTTGAAGGAATCCAAGTCCACGCCT
TGGACTTTTTTAACCTTCCAAGTCCCCATATCAAACCCAAACATATGCTGGTCCTCTACCAGAAAATTAA
AGAGGAAGCAGATAACTACGATGGAGTGGTGATCACACACGGAACCGATACTTTAGAGGAAACAGCCTAT
TTCCTTGATACCATGGAAGTTCCCCATATGCCTATCGTTCTAACAGGAGCCATGCGTAGCTCCAATGAGC
TCGGTAGTGATGGTGTTTATAATTACCTAAGTGCTTTACGAGTGGCCAGCGATGACAGGGCTGCTGACAA
AGGAGTTTTGGTCGTTATGAACGATGAAATCCACGCTGCCAAGTATGTCACCAAAACACATACGACTAAT
GTCAGCACCTTCCAGACTCCAACACATGGCCCCCTTGGTCTCATCATGAAACAGGAAATCCTCTACTTCA
AAACAGCTGAACCTCGTGTTCGCTTTGACCTTGATCACATACAAGGTTTAGTCCCTATCATCTCGGCTTA
TGCTGGTATGACAGATGAGCTGATTGATATGCTGGATTTAGAACACTTGGACGGTTTGATTATCCAAGCC
TTCGGAGCTGGTAATATTCCCAAAGAAACGGCTCAAAAATTAGAAAGCCTTCTGCAAAAAGGAATTCCAG
TCGCTCTGGTATCACGATGCTTTAACGGTATTGCCGAGCCTGTTTATGCATACCAGGGTGGGGGCGTACA
GTTGCAAAAAGCAGGCGTTTTCTTTGTTAAAGAACTCAACGCCCAAAAAGCTCGCTTGAAACTCCTCATC
GCCCTCAATGCCGGACTAACAGGACAGGCTTTGAAAGACTATATGGAAGGCTA
Protein Sequence 
>gi|15901821|ref|NP_346425.1| L-asparaginase [Streptococcus pneumoniae TIGR4] MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQVHALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPHMPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTHTTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELIDMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQGGGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1988 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0252EJ, under E: Amino acid transport and metabolism; J: Translation, ribosomal structure and biogenesis
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].