Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

phoP from Mycobacterium tuberculosis H37Rv

Victor ID 334
Gene Name phoP from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888772
NCBI Protein GI 15607897
Locus Tag Rv0757
Protein Accession NP_215271.1
Other Database IDs UniProtKB-ID: P71814_MYCTU
UniRef100: UniRef100_A1KGP0
UniRef90: UniRef90_A1KGP0
UniRef50: UniRef50_A0PWB4
UniParc: UPI00000D5049
EMBL: BX842574
EMBL-CDS: CAB02400.1
RefSeq_NT: NC_000962.2
HSSP: Q9WYN0
EnsemblGenome: EBMYCG00000002358.
EnsemblGenome_TRS: EBMYCT00000002360
EnsemblGenome_PRO: EBMYCP00000002360
GenomeReviews: AL123456_GR
KEGG: mtu:Rv0757
TubercuList: Rv0757
HOGENOM: HBG753323
OMA: VHTATNG
ProtClustDB: CLSK790716
Taxonomy ID 83332
Gene Starting Position 851607
Gene Ending Position 852350
Gene Strand (Orientation) +
Protein Name POSSIBLE TWO COMPONENT SYSTEM RESPONSE TRANSCRIPTIONAL POSITIVE REGULATOR PHOP
DNA Sequence 
>gi|57116681:851607-852350 Mycobacterium tuberculosis H37Rv, complete genome
AATGCGGAAAGGGGTTGATCTCGTGACGGCGGGAACCCCAGGCGAAAACACCACACCGGAGGCTCGTGTC
CTCGTGGTCGATGATGAGGCCAACATCGTTGAACTGCTGTCGGTGAGCCTCAAGTTCCAGGGCTTTGAAG
TCTACACCGCGACCAACGGGGCACAGGCGCTGGATCGGGCCCGGGAAACCCGGCCGGACGCGGTGATCCT
CGATGTGATGATGCCCGGGATGGACGGCTTTGGGGTGCTGCGCCGGCTGCGCGCCGACGGCATCGATGCC
CCGGCGTTGTTCCTGACGGCCCGTGACTCGCTACAGGACAAGATCGCGGGTCTGACCCTGGGTGGTGACG
ACTATGTGACAAAGCCCTTCAGTTTGGAGGAGGTCGTGGCCAGGCTGCGGGTCATCCTGCGACGCGCGGG
CAAGGGCAACAAGGAACCACGTAATGTTCGACTGACGTTCGCCGATATCGAGCTCGACGAGGAGACCCAC
GAAGTGTGGAAGGCGGGCCAACCGGTGTCGCTGTCGCCCACCGAATTCACCCTGCTGCGCTATTTCGTGA
TCAACGCGGGCACCGTGCTGAGCAAGCCTAAGATTCTCGACCACGTTTGGCGCTACGACTTCGGTGGTGA
TGTCAACGTCGTCGAGTCCTACGTGTCGTATCTGCGCCGCAAGATCGACACTGGGGAGAAGCGGCTGCTG
CACACGCTGCGCGGGGTGGGCTACGTACTGCGGGAGCCTCGATG
Protein Sequence 
>gi|15607897|ref|NP_215271.1| two component system response transcriptional positive regulator PhoP [Mycobacterium tuberculosis H37Rv] MRKGVDLVTAGTPGENTTPEARVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGNKEPRNVRLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILDHVWRYDFGGDVNVVESYVSYLRRKIDTGEKRLLHTLRGVGYVLREPR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: phoP mutant is attenuated in mice (Pérez et al., 2001).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Pérez et al., 2001: Pérez E, Samper S, Bordas Y, Guilhot C, Gicquel B, Martín C. An essential role for phoP in Mycobacterium tuberculosis virulence. Molecular microbiology. 2001; 41(1); 179-187. [PubMed: 11454210].