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SP_1970

Victor ID 3339
Gene Name SP_1970
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931885
NCBI Protein GI 15901793
Locus Tag SP_1970
Protein Accession NP_346397.1
Other Database IDs UniProtKB-ID: ASNA_STRPN
UniRef100: UniRef100_B5E2G2
UniRef90: UniRef90_Q04IJ8
UniRef50: UniRef50_A5U9S9
UniParc: UPI0000051A79
EMBL: AE005672
EMBL-CDS: AAK76037.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025272
EnsemblGenome_TRS: EBSTRT00000025272
EnsemblGenome_PRO: EBSTRP00000024364
GenomeReviews: AE005672_GR
KEGG: spn:SP_1970
TIGR: SP_1970
HOGENOM: HBG288146
OMA: LNDNLNG
ProtClustDB: PRK05425
BioCyc: SPNE170187-1:SP_1970-MONOMER
Taxonomy ID 170187
Gene Starting Position 1876951
Gene Ending Position 1877943
Gene Strand (Orientation) -
Protein Name asparagine synthetase AsnA
DNA Sequence 
>gi|194172857:1876951-1877943 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TCTACAAAATATTTTCGTAAGTATCGCGGACTTCTTGAGGCCAAACACTTGTTTGCACTTCTCCGATGTG
TCTCTTGCGAAGTAGGAACATGGCCATACGAGATTGTCCAATTCCTCCACCGATTGTCAATGGGAATAGA
CCATTCAACAAAGACTTGTGCCATTCCAATTCCAAGCGGTCTTCATCACCTGTAATTTCCACCTGACGTC
TAAGAGTTTCTTCATCTACACGAATTCCCATAGAAGACAACTCAAAGGCTCCACCTAAAGACTCATTCCA
GACAAGAATATCACCATTTAGACCCTTGTAGCCATTCTCAGACTCGCTTGTCCAGTCATCATAGTCTGGT
GCACGTCCATCGTGCGGTTTACCATCTGGCAACTCGCCACCGATACCAATCAAAAAGACGGCTCCAAATT
CTTTACAAATCGCATTTTCACGTTCTTTCGGTGTCAAGTCTGGGTAGCGTTCTACCAATTCTTCTGTATG
GATAAAGGTAATTTGTTTTGGCAAGATAGACTCGATGTCATAGCGGGCTTCAACAGCTAGCTCAGTCAGG
CGAATAGCCTTATAAATCTTCTCAACTGTTTCTTTTAGATAAACGATGTTACGCTTACCATTTGGGATAA
CCTTCTCCCAGTCCCACTGGTCAACATAAACAGAGTGGGTTGCATCCAAGGAATCCTCATCTGGACGAAG
GGCTTTCATGTGGACAAAGAGACCCTCTCCTTCACCAAAGCCAAAACGAGCCAAGGTGTGGCGTTTCCAT
TTAGCAAGTGAGTGCACCACTTCATAAGTAGCATCAGGGATTTGGAGAACCTTGACCGATACTGGATTTT
CCACACCAGACAGGTTGTCCTGCATTCCGTCACCGACCTTACTCAAGATAGGACCTTGAACTTCGACAAC
TTCTAGCTTATCTTTCAAATACTGGGTAAAAGTGTTTTTGACAAAGGAAATTTCTTCTTGTTGATGGATA
AAACTTTTCTTCA
Protein Sequence 
>gi|15901793|ref|NP_346397.1| asparagine synthetase AsnA [Streptococcus pneumoniae TIGR4] MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDYDDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLELEWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1970 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2502E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].