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SP_1343

Victor ID 3336
Gene Name SP_1343
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931860
NCBI Protein GI 15901197
Locus Tag SP_1343
Protein Accession NP_345801.1
Other Database IDs UniProtKB-ID: Q97Q83_STRPN
UniRef100: UniRef100_Q97Q83
UniRef90: UniRef90_B8ZK54
UniRef50: UniRef50_B8ZK54
UniParc: UPI00000517E9
EMBL: AE005672
EMBL-CDS: AAK75441.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025158.
EnsemblGenome_TRS: EBSTRT00000025158
EnsemblGenome_PRO: EBSTRP00000024250
GenomeReviews: AE005672_GR
KEGG: spn:SP_1343
TIGR: SP_1343
HOGENOM: HBG697687
OMA: VNNRGSS
ProtClustDB: CLSK560066
BioCyc: SPNE170187-1:SP_1343-MONOMER
Taxonomy ID 170187
Gene Starting Position 1265637
Gene Ending Position 1267577
Gene Strand (Orientation) -
Protein Name prolyl oligopeptidase family protein
DNA Sequence 
>gi|194172857:1265637-1267577 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TTCATAAGTTATTCCTTCCCACTTCTTCAAAGAAATAATTTAAAGTATCAATCATTAAGAGAACATCTGA
TGGAGTAAAACCTCCATGACCAGCTGCTTTGTTTAAATACAACAAACTTTTAACTCCAATAGAATTTAAT
TTCTTTGACCACTCTATCACTTCGTTATTATTAATATATGGGTCTTTCTCACCCAAAATATTAACTATAA
CAGTATTTGAGTCTCGTGCCTTTTCAATATTTTGCATAGGCGAATATGACTTTATATAAGCCTTTACTTC
AGGGTCTCTAATATCTCCCCACTCTGCTATTTCGGTCTTAGAAAGAGGATCATTTGGATTCTGAAGTGTA
TCATAAGGATTTATAAATGGCGAAAATAAGAGAATGCTTTGCAATAAATTTTTTTCCTCGTTCAACACCG
CACCAGCAATTATTCCACCTGCACTAGAAGTTATTAAACCTAATCGCTTACTGTCAATTACATCATTTTC
CCTTAAATAATTTACTCCCTCAATAAAATCTCTGATAGAATTCCATTTGTTTAACGCCTTTCCTGAGCGA
TACCATTCACCACCCAAATAGCCTCCACCTCTTACATGAACTATAGCATAAATAAAACCTGCATCTATTA
TAGATAACATAATTTCATCTAAATCAGAATTATCATTCTTACCATAAGCCCCATAGACACTTAGAATACA
TTTTTTTCTTCTTGGGAGCTCATCCGTATCTTCACTTTTCCAAAATAAAGAAATCGGTATGCTTACATCA
TAACTGTCTTTTTTAGTCCAAATCACCTTAGAAAAATATTTAGTATTATTCGATTTTATGATGGGTCTTT
CAAATTCAGTTTTTAATGTATTTTCTATTAAATCAAAACTAAGTATTTTTTCGTAAAAAGTTCTCCTCTC
TAAAAACAGAAGAACACGATCAGAAAATGAATTTTCATAAAGTGTTGTCTTTTCATCAAATGTTATCTTA
TTAACACTCAACTCCCTCAAACTATTATTTTTAAATGTAGCAAGATAAAAGACGGAATTCGCTGCGTTTG
AACAGTCTAAAAGGATATAACGTCCTATACAGTGAACTCTTCTAGCCCTATCTTGATATGGTATAGTAAT
AGAAACTCTGTCTCCCGAAGAAGTTTCCCTTAGAATTAGTTGATCTTTCTTTTCTTCAGTTGAAGAGAGC
CCAAGAAAGTACTGTGCTTTTTCTGTACTAAATAGAGCGATATCTCTAGGTGTTGGGGCTACCGTTTCTG
TGTAAGAGTGTCTAACAAAACCCGTCCGGTCGAAACTGTATAGAAAAATCCTGCCTTTCTGAAAGTCTAC
TGACTTTACAAAACAATTATTGCTATCAATGTGGACTATTTTTAATCGAAAAGAGCATTCGTTTTCTTCA
AACAGTTCCTCTTCTGTAAAGCTATCAAAAGATTTATAGAATAACTTACTTGGCCTCCCGTACTCTTTGG
AGCGAGTATACATAACACCGAATTTACCCAAATAGAACGAACTTTCTACTGAAATATCTTCAATGATAAA
TAACTCTTCCATAGTATATTTTTTTATTCCAATTAAATTAGTCGTACGCAGTGAGGATACAACCAAAACT
ATATAACTCTCATCAGATGAAATCCTAACATCCTGTAAGATACTATCATCTGGCAAAGTATATTTTTCCA
CATCAAAGACAATTTTAAGTGAATTTGAATTGTCTAAACTGGAAGAACTAACCTTAGGAATCCAGTCATT
ATCTTCGACATACCATTCCTTTATTACACCAGTATTGGGTATACTCCAATTATCAAATTGGTACCAATAT
CGCCCTCTCCTAAATATCAAAGAATTCCATTTTTTTAATTCCTGAAATGATGAAGAGATAGACCTCTTAT
AGTGTGTTTTTTCCTGTATTGTATTTAAAAATATTTCATTACTCTGATTCA
Protein Sequence 
>gi|15901197|ref|NP_345801.1| prolyl oligopeptidase [Streptococcus pneumoniae TIGR4] MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWYQFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDVRISSDESYIVLVVSSLRTTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKEYGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFDRTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSITIPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYENSFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYDVSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHVRGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGAVLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPMQNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTPSDVLLMIDTLNYFFEEVGRNNL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1343 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1770E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].