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SP_1286

Victor ID 3332
Gene Name SP_1286
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931800
NCBI Protein GI 15901146
Locus Tag SP_1286
Protein Accession NP_345750.1
Other Database IDs UniProtKB-ID: Q97QD3_STRPN
UniRef100: UniRef100_Q97QD3
UniRef90: UniRef90_B2IQ77
UniRef50: UniRef50_B2IQ77
UniParc: UPI00000517AD
EMBL: AE005672
EMBL-CDS: AAK75390.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026144.
EnsemblGenome_TRS: EBSTRT00000026144
EnsemblGenome_PRO: EBSTRP00000025236
GenomeReviews: AE005672_GR
KEGG: spn:SP_1286
TIGR: SP_1286
HOGENOM: HBG470187
OMA: STVLVPF
ProtClustDB: CLSK803808
BioCyc: SPNE170187-1:SP_1286-MONOMER
Taxonomy ID 170187
Gene Starting Position 1220465
Gene Ending Position 1221784
Gene Strand (Orientation) +
Protein Name uracil permease
DNA Sequence 
>gi|194172857:1220465-1221784 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGGGCTCTTTTTTGATGCCCAAAAGTGAGGTTTATATGAAACAAGAATCAACTGTTGATTTGTTACTA
GACGTTGACCAACGTCCTTCGGCTGGAAAAGGAATTCTCCTTAGTTTCCAACACGTTTTCGCCATGTTTG
GTGCGACCATCTTGGTACCATTGATTTTGGGAATGCCTGTATCTGTTGCCCTTTTTGCTTCAGGTGTTGG
AACACTCATCTACATGATTGCTACTGGTTTTAAAGTTCCAGTTTATCTAGGTTCTTCATTTGCCTTTATC
ACAGCTATGTCACTGGCTATGAAAGAAATGGGGGGGGATGTATCTGCTGCCCAAACAGGGGTTATCTTGA
CTGGTTTGGTCTATGTCCTTGTTGCTACCAGCATCCGATTTGTAGGAACAAAATGGATTGATAAACTCTT
GCCACCAATCATTATCGGTCCTATGATCATCGTTATCGGTCTTGGACTTGCAGGTTCAGCTGTTACCAAT
GCAGGTCTTGTAGCAGACGGAAATTGGAAAAATGCTCTGGTAGCCGTTGTTACTTTCCTAATTGCTGCCT
TTATCAATACAAAAGGAAAAGGCTTCCTACGAATCATTCCATTCCTCTTTGCCATTATCGGTGGTTACCT
TTTCGCACTAACTCTTGGCTTGGTTGACTTTACACCAGTTCTTAAAGCCAACTGGTTCGAAATTCCTGGT
TTCTACTTGCCATTTAGCACAGGTGGTGCCTTTAAAGAGTACAATCTTTACTTTGGTCCAGAAGCCATCG
CTATCTTGCCAATCGCTATCGTAACAATTTCTGAACATATCGGAGACCATACTGTTTTGGGTCAAATCTG
TGGTCGTCAATTCTTAAAAGAACCAGGTCTTCACCGTACTCTTCTTGGTGACGGTATCGCAACTTCTGTT
TCTGCCTTCCTTGGTGGACCAGCCAATACAACTTACGGAGAAAATACAGGGGTTATCGGTATGACTCGTA
TCGCTTCTGTCTCAGTTATCCGTAACGCTGCCTTCATCGCGATTGCCCTCAGCTTCCTTGGTAAATTCAC
TGCCTTGATTTCAACTATTCCAAACGCTGTACTTGGTGGTATGTCAATCCTTCTCTATGGGGTTATCGCC
AGCAATGGTTTGAAAGTCTTGATTAAAGAACGTGTTGATTTCGCTCAAATGCGAAACCTCATCATCGCAA
GTGCTATGTTGGTTCTTGGACTTGGAGGAGCTATCCTTAAACTTGGTCCAGTTACACTTTCAGGTACTGC
CCTTTCAGCCATGACAGGAATCATCTTGAACTTGATCTTGCCATACGAAAATAAAGACTA
Protein Sequence 
>gi|15901146|ref|NP_345750.1| uracil permease [Streptococcus pneumoniae TIGR4] MGSFLMPKSEVYMKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLILGMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGVILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNWKNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFEIPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEPGLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFLGKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGLGGAILKLGPVTLSGTALSAMTGIILNLILPYENKD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1286 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2233F, under F: Nucleotide transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].