Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

SP_1278

Victor ID 3329
Gene Name SP_1278
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931792
NCBI Protein GI 15901138
Locus Tag SP_1278
Protein Accession NP_345742.1
Other Database IDs UniProtKB-ID: PYRR_STRPN
UniRef100: UniRef100_Q04K45
UniRef90: UniRef90_Q04K45
UniRef50: UniRef50_B9MS19
UniParc: UPI00000517A5
EMBL: AE005672
EMBL-CDS: AAK75382.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000027181
EnsemblGenome_TRS: EBSTRT00000027181
EnsemblGenome_PRO: EBSTRP00000026273
GenomeReviews: AE005672_GR
KEGG: spn:SP_1278
TIGR: SP_1278
HOGENOM: HBG641958
OMA: ILDITLY
ProtClustDB: PRK05205
BioCyc: SPNE170187-1:SP_1278-MONOMER
Taxonomy ID 170187
Gene Starting Position 1213698
Gene Ending Position 1214219
Gene Strand (Orientation) -
Protein Name pyrimidine regulatory protein PyrR
DNA Sequence 
>gi|194172857:1213698-1214219 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TCTAAGCTTCTTCAGTAATCAGAACTCTGTCTTGGTCATCAAGTTCTGTCATCTCTACGATGATTTCTTC
AGAACGACTGGTTGGGATATTTTTTCCAACGTAATCTGGACGGATTGGCAATTCTCTATGTCCACGATCG
ACTAGAACTGCTAAACTCACACGCGCAGGACGACCATGACCGACAATATTATCAATAGCAGCACGGATGG
TACGACCTGTATAGAGCACATCATCCACCAAGATAACTTCGCGGTCTGTCACATCGACAGAAACCAAAGA
AGTATCTTCTCCACTTTTAACATCATCACGGAAAGGTTTAGTATCCAATTCCACAACAGGAACTGAAAGA
TTTTCTAACTGCTTCAAACGTTCTTGGATTCGGTGGGCAATAAAGACACCACGAGTTTTAATACCAGCCA
AGACGATCTTATTCAAATCTTTGTTGCGTTCGATAATCTCATAAGTAATACGCGTAATCGCTCGTTTGAC
GGTCAATTCGTCTACAACTTCTTTTGTTTTCA
Protein Sequence 
>gi|15901138|ref|NP_345742.1| bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase [Streptococcus pneumoniae TIGR4] MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1278 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2065F, under F: Nucleotide transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].