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SP_1175

Victor ID 3326
Gene Name SP_1175
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931689
NCBI Protein GI 15901040
Locus Tag SP_1175
Protein Accession NP_345644.1
Other Database IDs UniProtKB-ID: Q97QM8_STRPN
UniRef100: UniRef100_Q97QM8
UniRef90: UniRef90_Q8DPQ2
UniRef50: UniRef50_C1CED8
UniParc: UPI0000051734
EMBL: AE005672
EMBL-CDS: AAK75284.1
RefSeq_NT: NC_003028.3
PDB: 2CS7
EnsemblGenome: EBSTRG00000025556.
EnsemblGenome_TRS: EBSTRT00000025556
EnsemblGenome_PRO: EBSTRP00000024648
GenomeReviews: AE005672_GR
KEGG: spn:SP_1175
TIGR: SP_1175
HOGENOM: HBG697671
OMA: ISDEGDA
ProtClustDB: CLSK625890
BioCyc: SPNE170187-1:SP_1175-MONOMER
Taxonomy ID 170187
Gene Starting Position 1110874
Gene Ending Position 1113282
Gene Strand (Orientation) -
Protein Name hypothetical protein
DNA Sequence 
>gi|194172857:1110874-1113282 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATTAGTTTATTTTTTCCTTACTTACAGATGAAGGATTACTTCCTTTTAACAACGCAAGTAATTTTTCTGC
TTCTGCCATGATACTATTGTTATCCATAATTTGAAGAGTCAAATTATTTCGTAAACCAGCTAGAGTTTCT
GTTGCATTGGCTTTCAGACTAGAATCCGTTACTTTCGCAAGCAAAACTTCTGCTTCTTTGAGTTGGGCTT
CTACTTTTTCAGTCTCTACTTGAGGGACTTCTGGCTCAGCAGGTGTTTCCTCTACTGGCTCTTCATCCGC
TTTGAAGTTCTTATTTGGATCTTCACTGTGGTCTTTCTTGCCTAACACATGCTCACTGGCATTGCCCCAT
CCATCATTAGAATGTGGACGTTCGTCAGGGTGTTCTACGTAGTACTTAATCGTCGCAAACAAATCTTCCA
AGGTATAGCCATTTGGAGCTTTGTATGTGTGATCATCAAACCAAGCAAATTTAATATTATGGTAATGATC
CTTATGAGGAATAATCAAATTACCGTTTTTAACCTCAACTGTATGCTCAACCATATATGGAAGTCGAACG
AGTGGAATTCGTTTTTCCCCTTTCACACGATTGTAAATAGCTGCTGCACTATCTCCAGTTGGATTTGCTT
TAACATCTGCGTCTGGAGATGGAGGTAGGATACCTTTTTCTTTAGTATAGGCTTGAGCTGCAACTTTTTC
CTTATCAGAAAGGCTATCTTTTCCAATCCAGTGACTATGGCCCATATGAGGCGTTACATATGCATCTCCT
TCATCACTGATTATATCATGTTCATCAAAAATGTAACCATCTGACGTTGTATACTTATCAGCTAATTGAG
CAATACGAACTTCGTCTTCAGTATACTCAATTTGAGAATTTGGTTTGCCAAGTCGCTCTGGATGGGTAAT
TGGTGCTAGGAATGCCAATAAATCATCTACCAATTTTTCTTTATTAGTCGATTCATCATTCAAGCGTTCT
AATAATTTGTCTAAGGCTTGGAAATCAGAATTACGACCCTTATTTTCAAACAAGGCTTTATGAGCCTCAG
TTAACAGATTATATGCTTTATCATAAAATTCTTGGTCACGAGGAGCAACATTTTCTTTTTTAGCAGTTAA
AGTGTGTGAAACACTCTCTTGTTTTGATAACTTGCTTTCAAGATTTTTAACAGTTTCAGATGGTAAATCT
TTCGCAAAGACATAACGAGAGATGCCCTTTTCTTCGAATACATATCCTTCCCCAACTTTTCGTACCAGCT
GACTAACCAAAGAAGAATTTGAGTCTATTTTAAGATTTGGTGCAGGTTGCGGGCCTGGACTAGGTTCCGG
AGTCGGTTGTGGACTTGGTTGTTCTGGCCTTGAATCTGGTACCCAATGGTTTGAACGATAACGAAGGGGA
ATAATACGAGCGATTCGTTCTTCCAATTCAGACATTTGAGAGTAAGGGATGAAGTGGTAATGATCTCCGT
GTGGCACTGCAACACCTCTAGCTGTTCGACTTGTGATTTGTGCTGGATCAAAGACAAGGCCATCAGATTC
TACATGTCGTTGACTCAAAGGCAGTTTGTAGAGCTGTTTCAAGAGACTATCAATGTCATTACTTTGACTT
GCTTGACTGTTAGTGTTGCTGTTGTTGCTTGTGTTAGTATTTGTAGTTCCTGGATTGCTTACAGAAGGTA
CCCAGTTTGTTCTTGAAGTGTTATCGCTATTTTGTCGGCGATAGGTTCTTGAATTTGACAGATTTCCTCG
ACCAGATAGGAAGGCTTCTGCAGCAGCCAACTCGCTAGCTGATAACTCATTCTTAGGAATGTAATGGTAA
TGATCTCCATGAGGAACGATATAAGCATCACCAGTATCCTCTATGATATCAGAAGCATTAAAGATATAAC
CATCATCTGTAGTATAGCGTCCTTGCGAACGTGCCAAGGCAACAGCACCATCGTTTCTTGGAGTTCCACC
TTCACGATGTTGACTATGCTCTTGTTTTTGTCGATTGATTTCCTCTTTTGTACGGACGTTATCCGCGTGG
GCAGCATCCTTAAGGTAAACATAGTATTTTCCATCTACCTTGATAACATATCCACCCTTGACCTCATTAA
CAATATCCTCATCTTTTAGCTTATAGTTTGGATCTTTCATGAGTAATTCTTCACTGATGATAGCGTCATA
AGGAACCTTACCATTGTAATAATGATAGTGGTCGCCATGTGAAGTGACATAGCCTTGGTCTGTTATCTTG
ATGACGATTTGCTCAGCATTGATTCCTTCACGCTTGCTAACCTCATCAGGAGTCAAATTCTCCGTTTTTT
GCGTCGCTTGTTTTCCATCTATATAGGAAACACGATTATTTTCCTTAACCGTTCTAGCTTGATACAGTCC
CAACTCGTAAGAACAAACACTTAAAATCA
Protein Sequence 
>gi|15901040|ref|NP_345644.1| hypothetical protein SP_1175 [Streptococcus pneumoniae TIGR4] MILSVCSYELGLYQARTVKENNRVSYIDGKQATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSNTNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1175 mutant is attenuated in mice (Hava and Camilli, 2002).
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].