Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

SP_1154

Victor ID 3323
Gene Name SP_1154
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931668
NCBI Protein GI 15901019
Locus Tag SP_1154
Protein Accession NP_345623.1
Other Database IDs UniProtKB-ID: IGA1A_STRPN
UniRef100: UniRef100_Q97QP7
UniRef90: UniRef90_Q97QP7
UniRef50: UniRef50_Q59947
UniParc: UPI000005171F
EMBL: AE005672
EMBL-CDS: AAK75263.1
RefSeq_NT: NC_003028.3
MEROPS: M26.001
EnsemblGenome: EBSTRG00000025228
EnsemblGenome_TRS: EBSTRT00000025228
EnsemblGenome_PRO: EBSTRP00000024320
GenomeReviews: AE005672_GR
KEGG: spn:SP_1154
TIGR: SP_1154
HOGENOM: HBG703220
OMA: PEYTGVQ
ProtClustDB: CLSK883904
BioCyc: SPNE170187-1:SP_1154-MONOMER
Taxonomy ID 170187
Gene Starting Position 1083880
Gene Ending Position 1089894
Gene Strand (Orientation) +
Protein Name immunoglobulin A1 protease
DNA Sequence 
>gi|194172857:1083880-1089894 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGACTTGTATCT
GCAACGATTTCAAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTGGATGCTCAAGAAACTGCGG
GAGTTCACTATAAATATGTGGCAGATTCAGAGCTATCATCAGAAGAAAAGAAGCAGCTTGTCTATGATAT
TCCGACATACGTGGAGAATGATGATGAAACTTATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTG
GCGGAATTGCCAAATACTGGAAGCAAGAATGAGAGGCAAGCCCTAGTTGCTGGTGCTAGCTTAGCTGCTA
TGGGAATTTTAATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGGTATTACATTTAGTATTGGT
TGCAGGGATAGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTAAATTACAAT
ACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATTTCAGGTTACACTTATATTG
GATATATCAAAGAGGGAAAAACGACTTCTGAGTCTGAAGTAAGTAATCAAAAGAGTTCAGTTGCCACTCC
TACAAAACAACAAAAGGTGGATTATAATGTTACACCGAATTTTGTAGACCATCCATCAACAGTACAAGCT
ATTCAGGAACAAACACCTGTTTCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTA
CTGAATTAATCAATCCAAGAAAAGAAGAGAAACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAA
GAATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAAGAAAAGACTGGGGTAAATACATTAAATCCA
CAGGATGAAGTTTTATCAGGTCAATTGAACAAACCTGAACTCTTATATCGTGAGGAAACTATGGAGACAA
AAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTAGCTGAAGGAACTGTAAGAGTAAAACAAGA
AGGTAAATTAGGTAAGAAAGTTGAAATCGTCAGAATATTCTCTGTAAACAAGGAAGAAGTTTCGCGAGAA
ATTGTTTCAACTTCAACGACTGCGCCTAGTCCAAGAATAGTCGAAAAAGGTACTAAAAAAACTCAAGTTA
TAAAGGAACAACCTGAGACTGGTGTAGAACATAAGGACGTACAGTCTGGAGCTATTGTTGAACCCGCAAT
TCAGCCTGAGTTGCCCGAAGCTGTAGTAAGTGACAAAGGCGAACCAGAAGTTCAACCTACATTACCCGAA
GCAGTTGTGACCGACAAAGGTGAGACTGAGGTTCAACCAGAGTCGCCAGATACTGTGGTAAGTGATAAAG
GTGAACCAGAGCAGGTAGCACCGCTTCCAGAATATAAGGGTAATATTGAGCAAGTAAAACCTGAAACTCC
GGTTGAGAAGACCAAAGAACAAGGTCCAGAAAAAACTGAAGAAGTTCCAGTAAAACCAACAGAAGAAACA
CCAGTAAATCCAAATGAAGGTACTACAGAAGGAACCTCAATTCAAGAAGCAGAAAATCCAGTTCAACCTG
CAGAAGAATCAACAACGAATTCAGAGAAAGTATCACCAGATACATCTAGCAAAAATACTGGGGAAGTGTC
CAGTAATCCTAGTGATTCGACAACCTCAGTTGGAGAATCAAATAAACCAGAACATAATGACTCTAAAAAT
GAAAATTCAGAAAAAACTGTAGAAGAAGTTCCAGTAAATCCAAATGAAGGCACAGTAGAAGGTACCTCAA
ATCAAGAAACAGAAAAACCAGTTCAACCTGCAGAAGAAACACAAACAAACTCTGGGAAAATAGCTAACGA
AAATACTGGAGAAGTATCCAATAAACCTAGTGATTCAAAACCACCAGTTGAAGAATCAAATCAACCAGAA
AAAAACGGAACTGCAACAAAACCAGAAAATTCAGGTAATACAACATCAGAGAATGGACAAACAGAACCAG
AACCATCAAACGGAAATTCAACTGAGGATGTTTCAACCGAATCAAACACATCCAATTCAAATGGAAACGA
AGAAATTAAACAAGAAAATGAACTAGACCCTGATAAAAAGGTAGAAGAACCAGAGAAAACACTTGAATTA
AGAAATGTTTCCGACCTAGAGTTATACAGTTTGTCAAATGGTACTTATAAACAACACATTTCGTTAGAGC
AAGTTCCAAGCAATCCAAATAGCTACTTTGTTAAAGTGAAATCTTCTTCATTCAAAGATGTATACCTACC
AGTAGCATCAATATCAGAGGAAAGAAAAAATGATAAAATCCTTTATAAAATCACAGCAAAAGTAGAGAAG
CTTCAGCAGGAGATAGAAAGCAGATATAAAGATAATTTTACCTTCTATCTAGCTAAGAAGGGAACAGAAG
AAACAACAAACTTTACTTCCTTTAGTAATCTGGTCAAAGCTATAAACCAAAATCCCTCTGGAACCTATCA
TTTAGCGGCCAGCCTGAATGCTAACGAAGTGGAGCTTGGTCCTGATGAAAGATCCTATATCAAGGACACC
TTTACTGGTCGTTTAATCGGTGAAAAAGATGGCAAGAATTATGCTATCTATAATTTGAAAAAACCTCTGT
TTGAAAACTTGAGTGGTGCTACAGTAGAAAAACTGAGTCTAAAAAATGTTGCTATTTCAGGGAAAGATGA
TATCGGTTCACTGGCAAATGAAGCTCAGAATAACACAAAAATTAAGCAAGTTCACGTCGATGGTGTTCTG
GCTGGTGAACGTGGTATCGGTGGTTTGCTGGCTAAGGCTGAGCAATCAAGCATCACAGAGAGCAGTTTCA
AGGGAAGAATTATCAACACTTATGAAACGACTGCTGCCTACAATATCGGTGGTATGGTCGGTCATTTGAC
AGGTGACAAGGCTTTACTTACTAAGTCAAAAGCGACAGTAGCCATTTCATCTAACACAAATACTTCAGAT
CAGACTGTGGGTGGACTTGCAGGCCTAGTAGACCGAGATGCACAGATCCAAGATAGCTATGCTGAAGGTG
ATATCAACAATGTCAAGCACTTTGGTAGAGTCGCTGGAGTGGCAGGCAATTTGTGGGATCGAACTTCTGG
TGATGTTAGGCATGCTGGAAGTTTGACCAATGTTCTCAGCGATGTTAATGTAACCAACGGAAATGCCATC
ACTGGTTACCACTATAACGAAATGAAGGTAAAGGACACATTCAGCAGCAAGGCCAACAGAGTCTACAATG
TCACCTTGGTCAAGGATGAGGTCGTCAGCAAGGAATCCTTTGAAGAAAGAGGAACAATGCTAGATGCTTC
TCAAATTGCAAGCAAAAAAGCAGAAATCAATCCTCTCATTTTACCAACAGTGGAGCCACTTTCAACAAGT
GGCAAAAAAGACAGTGATTTTTCTAAGGTGGCCTATTATCAAGCTAAGCGCAACTTGACTTATAAAAACA
TTGAAAAATTGCTACCTTTCTACAACAAGGCAACCATCGTCAAATACGGAAACCTGGTCAATGAGAACAG
TCTTTTATATCAAAAAGAACTCTTGTCAGCAGTCATGATGAAGGACAACCAAGTCATCACAGACATTGTT
TCTAACAAACAGACTGCAAACAAACTCTTGCTTCACTACAAGGATGATTTATCTGAGAAGCTGGATCTCA
AATACCAGAATGATTTCGCCAAATTAGCAGAATATAGTCTGGGCAATACTGGACTTCTCTATACGCCAAA
CCAATTCCTGTATGACCAAACCTCTATCATCAAGCAAGTCTTACCTGACTTACAAAAGGTTGACTATCAT
TCAGAAGCCATCAGAAAGACGCTGGGTATTTCTCCAAACGTCAAGCAAACTGAGCTCTATCTAGAAGACC
AGTTCGCCAAAACAAAACAACAACTGGAAGACAGTTTGAAAAAACTCTTGTCAGCGGATGCTGGACTGGC
TAGTGCTAACCCCGTCACTGAAGGTTATCTTGTAGATAAAATCAAACGCAACAAGGAAGCCTTGCTACTT
GGCTTGACCTATCTGGAACGGTGGTATAACTTTAGCTATGGTCAGGTGAATGTCAAAGACCTAGTTCTGT
ACCATTTGGACTTCTTTGGTAAGGGGAATGCTTCACCATTAGATACTCTGATTGAGTTGGGTAAATCTGG
CTTTAACAATCTTCTAGCTAAGAATAATGTCGATACTTATGGTATCAGTCTTGCCAGTCAACATGGAACG
ACAGATTTGTTTAGCACGCTGGAACATTACCGAAAAGTCTTTTTACCAAATACAAGCAATAATGACTGGT
TTAAATCAGAGACTAAGGCTTACATTGTCGAAGAAAAATCCACTATCGAAGAGGTGAAAACGAAGCAAGG
GTTAGCTGGCACCAAGTATTCTATCGGTGTTTATGATCGTATCACGAGTGCCACATGGAAATACCGCAAT
ATGGTCTTGCCTCTCCTGACCTTGCCAGAGAGATCCGTATTTGTCATCTCGACCATGTCTAGTCTAGGAT
TTGGAGCTTATGATCGCTACCGCAGTAGTGACCATAAAGCGGGCAAGGCTCTCAATGATTTTGTTGAAGA
AAATGCGCGTGAAACAGCCAAACGTCAGCGAGATCACTACGATTATTGGTATCGTATTTTAGACGACAAT
GCACGTGAAAAACTTTATAGAAATATTTTGCTTTACGATGCTTATAAATTTGGCGATGATAATACCGTAG
GGAAAGCTACAGAAGTGGCAGATTTTGATAATCCAAATCCTGCAATGCAACATTTCTTTGGACCTGTTGG
AAATAAAGTTGGGCATAATCAACACGGTGCTTATGCTACAGGTGATGCAGTTTATTATATGGGTTATCGA
ATGTTGGATAAGGATGGAGCTATTACTTATACGCATGAGATGACACATGACTCAGATCAGGACATTTATC
TTGGAGGATATGGTCGAAGAAGTGGCTTGGGACCAGAGTTCTTTGCTAAAGGATTATTACAAGCACCAGA
CCATCCAGATGATGCGACCATTACCATCAACTCCATCTTGAAACATTCAAAATCTGATAGTACAGAAAGT
CGACGATTACAAGTACTTGATCCAACTACAAGATTTAATAATGCAGATGATTTGAAGCAATATGTCCACA
ACATGTTTGACGTTGTTTATATGTTGGAATATCTCGAAGGAAATTCAATTCTTAAATTGGATACGAATCA
AAAACAACAACTTCTTAGAAAAGTTACAAATGAGTACCATCCTGATCCTGATGGAAATAAGGTCTATGCA
ACAAATGTTGTCAGAAATCTAACAGTAGAAGAAGTTGAAAGACTACGTTCATTCAATGATTTGATTGATA
ATAATATTCTTTCGTCTAGGGAATATGCCTCAGGTAAATACGAAAGAAATGGCTACTTCACTATTAAGTT
ATTTGCACCGATTTATGCTGCATTAAGTAATGATATAGGAACACCAGGTGACCTGATGGGACGTCGTATA
GCCTATGAACTACTAGCTGCTAAAGGCTTTAAAGATGGTATGGTACCATATATCTCAAACCAATACGAAG
AAGAAGCCAAACAAAAGGGCAAGACAATCAATCTCTACGGTAAAACAAGAGGTTTGGTTACAGATGACTT
GGTTTTGGAAAAGGTATTTAATAACCAATATCATACTTGGAGTGAGTTTAAGAAAGCTATGTATCAAGAA
CGACAAGATCAGTTTGATAGATTGAACAAAGTTACTTTTAATGATACAACACAGCCTTGGCAAACATTTG
CCAAGAAAACTACAAGCAGTGTAGATGAATTACAGAAATTAATGGACGTTGCTGTTCGTAAGGATGCAGA
ACACAATTACTACCATTGGAATAACTACAATCCAGACATAGATAGTGAAGTCCACAAGCTCAAGAGAGCA
ATCTTTAAAGCCTATCTTGACCAAACAAATGATTTTAGAAGTTCAATTTTTGAGAATAAAAAATA
Protein Sequence 
>gi|15901019|ref|NP_345623.1| immunoglobulin A1 protease [Streptococcus pneumoniae TIGR4] MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAAMGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETMETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSKNTGEVSSNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGNSTEDVSTESNTSNSNGNEEIKQENELDPDKKVEEPEKTLELRNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKDDIGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKAEQSSITESSFKGRIINTYETTAAYNIGGMVGHLTGDKALLTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFSSKANRVYNVTLVKDEVVSKESFEERGTMLDASQIASKKAEINPLILPTVEPLSTSGKKDSDFSKVAYYQAKRNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVMMKDNQVITDIVSNKQTANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQFLYDQTSIIKQVLPDLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLKKLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYHLDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVHNMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNLTVEEVERLRSFNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDIGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEEAKQKGKTINLYGKTRGLVTDDLVLEKVFNNQYHTWSEFKKAMYQERQDQFDRLNKVTFNDTTQPWQTFAKKTTSSVDELQKLMDVAVRKDAEHNYYHWNNYNPDIDSEVHKLKRAIFKAYLDQTNDFRSSIFENKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1154 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG3583S, under S: Function unknown
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].