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mtrA

Victor ID 332
Gene Name mtrA
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888743
NCBI Protein GI 15610382
Locus Tag Rv3246c
Protein Accession NP_217763.1
Other Database IDs UniProtKB-ID: MTRA_MYCTU
UniRef100: UniRef100_P0A5Z5
UniRef90: UniRef90_P0A5Z5
UniRef50: UniRef50_P0A5Z5
UniParc: UPI000012F836
EMBL: U01971
EMBL: BX842582
EMBL: AE000516
EMBL-CDS: AAB07804.1
EMBL-CDS: CAB08347.1
EMBL-CDS: AAK47686.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 2GWR
PDB: 3NHZ
EnsemblGenome: EBMYCG00000000173
EnsemblGenome_TRS: EBMYCT00000000173
EnsemblGenome_PRO: EBMYCP00000000173
EnsemblGenome: EBMYCG00000070791
EnsemblGenome_TRS: EBMYCT00000070796
EnsemblGenome_PRO: EBMY
Taxonomy ID 83332
Gene Starting Position 3626662
Gene Ending Position 3627348
Gene Strand (Orientation) -
Protein Name TWO COMPONENT SENSORY TRANSDUCTION TRANSCRIPTIONAL REGULATORY PROTEIN MTRA
DNA Sequence 
>gi|57116681:3626662-3627348 Mycobacterium tuberculosis H37Rv, complete genome
ATCACGGAGGTCCGGCCTTGTACCCCACTCCTCGAACGGTCAGCACCACAGTCGGGTTCTCGGGATCCTT
TTCGACCTTGGCCCGCAGACGCTGGACATGCACGTTCACCAGCCTGGTATCGGCTGGGTGCCGGTAACCC
CATACCTGTTCGAGCAGCACATCACGAGTAAACACCTGGCGCGGCTTGCGCGCCAATGCGACCAACAGGT
CGAATTCCAGCGGTGTCAACGAGATCTGCTCACCGTTGCGAGTGACCTTGTGCGCCGGTACGTCGATTTC
TACGTCGGCGATGGACAGCATCTCGGCGGGTTCGTCGTCGTTGCGGCGCAGCCGCGCCCGCACCCGCGCA
ACCAGCTCCTTGGGCTTGAACGGCTTCATGATGTAGTCGTCGGCGCCCGACTCCAGACCCAGCACCACAT
CCACGGTGTCGGTCTTTGCGGTGAGCATCACGATCGGAACACCGGAATCGGCGCGCAACACCCGGCACAC
GTCGATGCCGTTCATACCGGGCAGCATCAAATCCAATAACACCAGATCGGGGCGCAGCTCGCGCACCGCG
GTCAGAGCCTGAGTACCGTCGCCGATGACCGCGGTGTCGAAGCCTTCCCCCCGCAGCACGATGGTGAGCA
TCTCAGCCAACGAAGCGTCGTCGTCAACGACCAAAATCCTTTGCCTCATGGTGTCCA
Protein Sequence 
>gi|15610382|ref|NP_217763.1| two component DNA-binding response regulator MtrA [Mycobacterium tuberculosis H37Rv] MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].