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SP_1029

Victor ID 3309
Gene Name SP_1029
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931543
NCBI Protein GI 15900900
Locus Tag SP_1029
Protein Accession NP_345504.1
Other Database IDs UniProtKB-ID: Y1029_STRPN
UniRef100: UniRef100_Q97R12
UniRef90: UniRef90_Q8DPY7
UniRef50: UniRef50_Q8DPY7
UniParc: UPI00000516B0
EMBL: AE005672
EMBL-CDS: AAK75144.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025705
EnsemblGenome_TRS: EBSTRT00000025705
EnsemblGenome_PRO: EBSTRP00000024797
GenomeReviews: AE005672_GR
KEGG: spn:SP_1029
TIGR: SP_1029
HOGENOM: HBG690163
OMA: RKGCDEA
ProtClustDB: CLSK877201
BioCyc: SPNE170187-1:SP_1029-MONOMER
Taxonomy ID 170187
Gene Starting Position 970424
Gene Ending Position 972055
Gene Strand (Orientation) +
Protein Name RNA methyltransferase, TrmA family
DNA Sequence 
>gi|194172857:970424-972055 Streptococcus pneumoniae TIGR4 chromosome, complete genome
AATGTTAAAGAAAAATGATATTGTAGAAGTTGAAATTGTTGATTTGACCCATGAAGGGGCAGGAGTTGCC
AAGGTAGATGGTTTGGTCTTTTTTGTAGAGAATGCTTTACCGAGTGAAAAAATTCTCATGCGTGTCCTCA
AGGTCAATAAAAAGATTGGCTTTGGAAAAGTTGAAAAATACCTTGTCCAGTCACCACACCGTAATCAAGA
TCTAGATTTGGCTTACCTGCGTTCAGGAATCGCGGATTTAGGACACCTTTCTTATCCAGAACAGCTCAAG
TTTAAAACCAAGCAAGTCAAGGACAGTCTCTACAAGATTGCTGGAATTGCAGATGTAGAAGTTGCTGAAA
CGCTTGGTATGGAACATCCAGTCAAGTATCGCAATAAGGCGCAGGTGCCCGTTCGTCGAGTGAATGGTGT
CTTGGAAACAGGATTTTTCCGTAAGAATTCGCATAACCTCATGCCCCTTGAAGATTTCTTTATCCAGGAT
CCTGTCATTGACCAAGTCGTAGTAGCTCTTCGAGACCTGCTCCGTCGTTTTGATTTAAAACCTTATGACG
AAAAGGAACAGTCTGGATTGATTCGGAATCTTGTGGTGCGTCGTGGTCACTATTCAGGACAAATCATGGT
CGTTTTGGTGACAACTCGTCCAAAAGTTTTTCGTGTTGACCAATTGATTGAACAAGTTATCAAGCAGTTC
CCAGAGATTGTGTCTGTCATGCAAAATATCAACGACCAGAATACCAATGCGATTTTTGGTAAGGAGTGGC
GCACTCTTTATGGTCAAGACTATATTACGGACCAGATGTTGGGAAATGACTTCCAAATCGCTGGCCCAGC
CTTTTACCAAGTCAATACTGAAATGGCGGAGAAACTCTATCAAACAGCCATTGACTTTGCAGAGTTAAAA
AAAGATGATGTGATTATTGATGCCTATTCTGGTATTGGAACCATTGGTTTATCAGTCGCCAAGCATGTCA
AAGAAGTCTACGGTGTTGAACTGATTCCAGAAGCAGTAGAGAATAGCCAGAAGAATGCTTCTTTGAACAA
GATTACTAATGCCCACTATGTCTGTGACACGGCTGAAAATGCCATGAAGAAATGGCTCAAGGAAGGTATT
CAACCAACCGTTATCTTGGTTGATCCTCCACGCAAGGGCTTGACAGAAAGCTTTATCAAAGCAAGCGCCC
AAACAGGAGCCGATCGCATCGCCTATATCTCCTGCAATGTCGCAACCATGGCGCGTGATATTAAACTATA
CCAAGAGTTGGGATATGAATTGAAGAAAGTCCAGCCGGTGGATCTATTTCCTCAAACGCATCACGTCGAG
ACGGTAGCACTTTTGTCCAAACTCGATGTCGATAAGCACATAAGTGTTGAAATTGAGCTGGATGAGATGG
ATTTGACAAGTGCGGAGAGCAAAGCAACATATGCTCAAATCAAAGAATATGTTTGGAATAAATTTGAATT
AAAAGTTTCGACATTATATATTGCACAGATAAAAAAGAAATGTGGAATAGAATTACGAGAACATTACAAC
AAGTCTAAAAAGGATAAACAAATTATTCCACAGTGTACACCTGAAAAAGAAGAAGCCATCATGGATGCTT
TGAGACACTTCAAAATGATTTA
Protein Sequence 
>gi|15900900|ref|NP_345504.1| RNA methyltransferase [Streptococcus pneumoniae TIGR4] MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSKLDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1029 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG2265J, under J: Translation, ribosomal structure and biogenesis
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].