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SP_1018

Victor ID 3307
Gene Name SP_1018
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931532
NCBI Protein GI 15900889
Locus Tag SP_1018
Protein Accession NP_345493.1
Other Database IDs UniProtKB-ID: KITH_STRPN
UniRef100: UniRef100_Q8DPZ6
UniRef90: UniRef90_Q8DPZ6
UniRef50: UniRef50_Q8DPZ6
UniParc: UPI00000516A6
EMBL: AE005672
EMBL-CDS: AAK75133.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025720
EnsemblGenome_TRS: EBSTRT00000025720
EnsemblGenome_PRO: EBSTRP00000024812
GenomeReviews: AE005672_GR
KEGG: spn:SP_1018
TIGR: SP_1018
HOGENOM: HBG522108
OMA: FRYGAMN
ProtClustDB: PRK04296
BioCyc: SPNE170187-1:SP_1018-MONOMER
Taxonomy ID 170187
Gene Starting Position 962373
Gene Ending Position 962972
Gene Strand (Orientation) +
Protein Name thymidine kinase
DNA Sequence 
>gi|194172857:962373-962972 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CATGGCACAGTTGTACTATCGTTATGGGACCATGAACTCTGGTAAAACGATTGAGATTCTCAAAGTGGCC
TATAACTACGAGGAGCAAGGAAAAGGTGTTGTGATTATGACCTCGGCTCTGGATACGCGTGACGGCGTTG
GCTATGTGTCGAGTCGAATTGGCATGAAACGCCCTGCCCTTGCGATTGAGGAAACAACGGATATCTTTGG
CTATATCCGAGACCTACCAGAAAAACCTTACTGTGTTTTGGTCGATGAAGCCCAGTTTCTCAAACGCCAC
CATGTTTACGACCTAGCTCGTGTTGTGGACGAGTTAGACATACCCGTCATGGCTTTTGGCTTGAAAAATG
ACTTTCGCAATGAATTGTTCGAAGGTTCCAAATATCTCTTGCTTTTAGCAGACAAGATTGACGAAATCAA
GACCATCTGTCAGTATTGCAAGAAAAAGGCGACCATGGTGTTGCGAACACAGGATGGACTGCCCGTTTAC
GATGGAGAACAGATCCAGATTGGTGGTAACGAAACCTATATCTCAGTTTGCCGTAAACATTATTTTGCGC
CAATGATAACCTCTAACAAGGAGCAAAACTATGACAATTG
Protein Sequence 
>gi|15900889|ref|NP_345493.1| thymidine kinase [Streptococcus pneumoniae TIGR4] MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRDGVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVVDELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGLPVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1018 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG1435F, under F: Nucleotide transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].