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SP_0978

Victor ID 3303
Gene Name SP_0978
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931491
NCBI Protein GI 15900855
Locus Tag SP_0978
Protein Accession NP_345459.1
Other Database IDs UniProtKB-ID: Q97R54_STRPN
UniRef100: UniRef100_E0SZ59
UniRef90: UniRef90_E0SZ59
UniRef50: UniRef50_E0SZ59
UniParc: UPI000005167A
EMBL: AE005672
EMBL-CDS: AAK75099.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025780.
EnsemblGenome_TRS: EBSTRT00000025780
EnsemblGenome_PRO: EBSTRP00000024872
GenomeReviews: AE005672_GR
KEGG: spn:SP_0978
TIGR: SP_0978
HOGENOM: HBG697208
OMA: YLTENES
ProtClustDB: CLSK876916
BioCyc: SPNE170187-1:SP_0978-MONOMER
Taxonomy ID 170187
Gene Starting Position 923558
Gene Ending Position 924511
Gene Strand (Orientation) +
Protein Name competence protein CoiA
DNA Sequence 
>gi|194172857:923558-924511 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCA
TACACCTGCCCAGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCC
ATAAATCCTTAAAAGACTGTGATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATC
CCTCTATCACTGGTTGAAAAAAGAGACAAAGGTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATT
GCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCAGTGTAGTCCCTTGCCTCAGAAAGTCCTTA
AAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGCTGGGTCAAAAACTGTGGCT
CAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTTTATGTTTGG
GAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCC
ATTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAG
ACAAAAAATATCTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTAT
TATCAAAATCTCTTTTGGATGAAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATG
GACTGAAAGAATGGTATCCACAAATTCGACCAATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGAC
TAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATCCTCAAAATGATTGGCAAAAGCTTTATCCA
CCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATA
Protein Sequence 
>gi|15900855|ref|NP_345459.1| competence protein CoiA [Streptococcus pneumoniae TIGR4] MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGFYVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: CoiA mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG4469R, under R: General function prediction only
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].