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aroD

Victor ID 3302
Gene Name aroD
Sequence Strain (Species/Organism) Streptococcus pneumoniae
NCBI Gene ID 931457
NCBI Protein GI 15901231
Locus Tag SP_1377
Protein Accession NP_345835.1
Other Database IDs UniProtKB-ID: AROD_STRPN
UniRef100: UniRef100_Q04JX0
UniRef90: UniRef90_Q04JX0
UniRef50: UniRef50_Q1JCG7
UniParc: UPI000005180E
EMBL: AE005672
EMBL-CDS: AAK75475.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000026565
EnsemblGenome_TRS: EBSTRT00000026565
EnsemblGenome_PRO: EBSTRP00000025657
GenomeReviews: AE005672_GR
KEGG: spn:SP_1377
TIGR: SP_1377
HOGENOM: HBG732926
OMA: IAKLAVM
ProtClustDB: PRK02412
BioCyc: SPNE170187-1:SP_1377-MONOMER
Taxonomy ID 170187
Gene Starting Position 1299715
Gene Ending Position 1300392
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate dehydratase
DNA Sequence 
>gi|194172857:1299715-1300392 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATCAAGCTTCATCCAAAATCTCCCTGATTTTTTTCATGCTAGCTAGAGAAATCTGCCCAGGGGCACTAAC
CTCATCCAGACTGGCAAAAGACCAACTCGAACCAGTCACATCCGCAGTGATACGAGAGACCTTGCCCACC
TTACCCATAGAAATGGTCACATATTCCTGTTCAGGATTGAGGGTTTTAAAGCCTCGTGTATAGTTCATCA
AGTCTAAGACATCCTGCTCCGTGTGAGCCATCACCGCAACCTTAACAAGTTTTGGATTTAGGATCGTCAA
CTCTGACAAGATTTCCATCATGTTCTCAGGTGTTTCTTGGAAATTATGGTAACTCAAAACAAGATTTGGG
AAGTCCAGCATTTCCTCAAAAACATCCTTGTAGCTATAGTACTCAAAATCAATATAGTCTGGTTGATAGA
GTTGCGCAACTTCCTTGATTAGATGGATATACTCTTCTGGAGAAAGGTCGATTTCTCCACCTTCGGAGCG
AGTTCGTAGCGTGAAAACCAACTCACGGCCTGCGAATTTTTCAAAAATGGCTGGAGCTACCTGCAAAATC
GCTTCTTTAGGCAGATAGTCGGCACGCCATTCAATGATGTCGGCATCCAGGTACCTCGTGGCATCCAGAG
CCTGAGCCTCCTCTAAACTTCTTGGCATTACTGAAACGATTAATTTCA
Protein Sequence 
>gi|15901231|ref|NP_345835.1| 3-dehydroquinate dehydratase [Streptococcus pneumoniae TIGR4] MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroD mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0710E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].