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SP_1382

Victor ID 3301
Gene Name SP_1382
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931456
NCBI Protein GI 15901236
Locus Tag SP_1382
Protein Accession NP_345840.1
Other Database IDs UniProtKB-ID: Q97Q49_STRPN
UniRef100: UniRef100_C1CQX4
UniRef90: UniRef90_B1ICI2
UniRef50: UniRef50_A3CMN5
UniParc: UPI0000051813
EMBL: AE005672
EMBL-CDS: AAK75480.1
RefSeq_NT: NC_003028.3
HSSP: P06278
EnsemblGenome: EBSTRG00000027128.
EnsemblGenome_TRS: EBSTRT00000027128
EnsemblGenome_PRO: EBSTRP00000026220
GenomeReviews: AE005672_GR
KEGG: spn:SP_1382
TIGR: SP_1382
HOGENOM: HBG284842
OMA: VWIPPAY
ProtClustDB: PRK09441
BioCyc: SPNE170187-1:SP_1382-MONOMER
Taxonomy ID 170187
Gene Starting Position 1304782
Gene Ending Position 1306236
Gene Strand (Orientation) +
Protein Name cytoplasmic alpha-amylase
DNA Sequence 
>gi|194172857:1304782-1306236 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGCAAAATCAAACACTCATGCAATACTTTGAATGGTATCTGCCCCACGACGGTCAACACTGGACGCGT
CTGGCTGAAAATGCTCCACACCTAGCTCATCTGGGGATCAGTCACGTCTGGATGCCACCAGCCTTCAAGG
CAACCAACGAAAAAGATGTCGGCTATGGGGTCTATGACTTATTTGACTTAGGAGAGTTCAACCAAAAAGG
GACTGTCCGCACCAAGTATGGTTTCAAAGAAGACTATCTTCAAGCCATTCAAGCCCTTAAAGCACAGGGA
ATTCAACCTATGGCCGATGTAGTTCTCAACCACAAGGCTGCTGCCGATCACAGGGAAGCCTTTCAGGTTA
TCGAAGTTGATCCTGTAGACCGTACAGTTGAACTTGGAGAACCCTTCACCATCAATGGCTGGACTAGTTT
TACCTTCGATGGTCGCCAAGATACCTATAATGGCTTCCACTGGCATTGGTACCACTTCACCGGTACAGAC
TACGATGCCAAACGCAGTAAATCTGGGATTTATCTGATCCAAGGGGACAACAAGGGCTGGGCCAACGAGG
AATTGGTCGATAACGAAAACGGAAACTACGACTACCTCATGTATGCCGACCTAGACTTTAAACATCCTGA
AGTCATCCAAAACATCTATGACTGGGCTGATTGGTTCATGGAAACGACTGGTGTAGCTGGTTTCCGTTTG
GATGCCGTTAAGCATATTGACTCTTTCTTTATGCGCAACTTCATCCGCGATATGAAGGAAAAATACGGTG
ACGATTTCTATGTTTTTGGTGAATTTTGGAACCCAGACAAGGAAGCCAATCTGGACTATCTCGAAAAAAC
GGAAGAACACTTTGACCTTGTCGATGTTCGTCTCCACCAGAATCTCTTTGAAGCCAGTCAAGCTGGCGCA
AACTATGACCTTCGTGGCATTTTCACAGATAGCCTGGTTGAACTCAAGCCTGACAAGGCTGTGACTTTTG
TCGACAACCACGATACCCAACGAGGACAAGCCCTTGAGTCTACCGTTGAAGAATGGTTCAAGCCAGCAGC
CTATGCCCTCATTTTGTTACGCCAAGACGGCCTTCCATGTGTCTTTTACGGAGACTACTATGGGATTTCA
GGGCAGTATGCTCAAGAAGATTTCAAAGAAATCCTTGACCGCCTCCTAGCCATCCGAAAAGATTTGGCCT
ATGGAGAACAAAATGACTACTTTGACCATGCTAACTGTATCGGTTGGGTACGTTCAGGTGCTGAAAATCA
ATCCCCAATCGCAGTCCTTATCTCAAATGACCAAGAAAACAGCAAGTCAATGTTTGTCGGTCAAGAATGG
ACTAATCAAACCTTTGTAGATTTACTTGGTAACCACCAAGGTCAAGTTACAATTGATGAGGAAGGTTATG
GACAATTCCCTGTCTCAGCTAGATCCGTAAGTGTCTGGGCAGTCAATACCATCTA
Protein Sequence 
>gi|15901236|ref|NP_345840.1| alpha-amylase [Streptococcus pneumoniae TIGR4] MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPAFKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVLNHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFTGTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDWADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDYLEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQRGQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIRKDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVDLLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1382 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0366G, under G: Carbohydrate transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].