Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

spa33 from Shigella flexneri 5a

Victor ID 33
Gene Name spa33 from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876456
NCBI Protein GI 13449099
Locus Tag pWR501_p160
Protein Accession NP_085315.1
Other Database IDs UniProtKB-ID: SPAO_SHIFL
UniRef100: UniRef100_P0A1K9
UniRef90: UniRef90_P0A1K9
UniRef50: UniRef50_P0A1K9
UniParc: UPI0000135DA0
EMBL: M81458
EMBL: D13663
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: AAA26543.1
EMBL-CDS: BAA02828.1
EMBL-CDS: CAC05827.1
EMBL-CDS: AAK18471.1
EMBL-CDS: AAL72304.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093078
EnsemblGenome_TRS: EBESCT00000094034
EnsemblGenome_PRO: EBESCP00000090241
GenomeReviews: AF386526_GR
KEGG: sfl:CP0152
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 124833
Gene Ending Position 125714
Gene Strand (Orientation) +
Protein Name Type III secretion protein
DNA Sequence 
>gi|13448939:124833-125714 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
AATGCTAAGAATTAAACATTTTGACGCTAACGAAAAACTACAGATTTTATATGCAAAGCAACTCTGCGAG
CGTTTTTCGATTCAGACATTCAAAAATAAATTTACAGGCAGTGAAAGTTTAGTCACTCTTACTTCCGTGT
GTGGGGATTGGGTAATTCGTATTGATACATTATCTTTTTTGAAAAAAAAATACGAGGTATTTTCAGGATT
TTCTACACAAGAATCTTTACTGCATTTATCAAAATGTGTCTTTATAGAGTCGTCATCTGTATTTTCGATT
CCAGAACTGTCTGATAAGATTACTTTCCGGATCACGAATGAAATCCAGTATGCAACTACTGGGAGTCATT
TATGCTGTTTTTCCTCTTCTTTAGGTATTATTTATTTTGACAAGATGCCGGTATTACGTAATCAAGTTTC
TCTTGACTTATTGCATCATCTTTTAGAGTTTTGCTTAGGTTCATCTAATGTAAGGCTGGCTACTTTAAAA
AGAATTCGCACTGGTGATATAATCATAGTTCAGAAACTTTATAATTTATTATTGTGTAATCAAGTTATTA
TTGGGGATTATATTGTGAATGATAATAATGAGGCAAAAATTAATCTGTCAGAAAGTAATGGTGAGTCAGA
ACACACAGAAGTTTCTTTGGCATTATTCAATTATGATGATATCAATGTAAAAGTGGACTTTATTCTTTTA
GAAAAAAATATGACAATCAATGAACTAAAAATGTATGTAGAAAACGAATTATTCAAGTTTCCCGATGACA
TAGTTAAACATGTAAATATTAAAGTAAATGGTTCTTTGGTTGGGCATGGGGAACTTGTTTCTATTGAGGA
TGGTTATGGTATCGAGATTAGTTCTTGGATGGTAAAGGAGTA
Protein Sequence 
>gi|13449099|ref|NP_085315.1| Type III secretion protein [Shigella flexneri 5a str. M90T] MLRIKHFDANEKLQILYAKQLCERFSIQTFKNKFTGSESLVTLTSVCGDWVIRIDTLSFLKKKYEVFSGFSTQESLLHLSKCVFIESSSVFSIPELSDKITFRITNEIQYATTGSHLCCFSSSLGIIYFDKMPVLRNQVSLDLLHHLLEFCLGSSNVRLATLKRIRTGDIIIVQKLYNLLLCNQVIIGDYIVNDNNEAKINLSESNGESEHTEVSLALFNYDDINVKVDFILLEKNMTINELKMYVENELFKFPDDIVKHVNIKVNGSLVGHGELVSIEDGYGIEISSWMVKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spa33 mutants are unable to secrete effectors necessary to cell invasion (Morita-Ishihara et al., 2006).
References
Morita-Ishihara et al., 2006: Morita-Ishihara T, Ogawa M, Sagara H, Yoshida M, Katayama E, Sasakawa C. Shigella Spa33 is an essential C-ring component of type III secretion machinery. The Journal of biological chemistry. 2006; 281(1); 599-607. [PubMed: 16246841].