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sigC from Mycobacterium tuberculosis H37Rv

Victor ID 329
Gene Name sigC from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 888723
NCBI Protein GI 15609206
Locus Tag Rv2069
Protein Accession NP_216585.1
Other Database IDs UniProtKB-ID: RPSC_MYCTU
UniRef100: UniRef100_P66810
UniRef90: UniRef90_P66810
UniRef50: UniRef50_P66810
UniParc: UPI000013481D
EMBL: BX842578
EMBL: AE000516
EMBL-CDS: CAA98224.1
EMBL-CDS: AAK46409.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 2O7G
PDB: 2O8X
EnsemblGenome: EBMYCG00000003421
EnsemblGenome_TRS: EBMYCT00000003423
EnsemblGenome_PRO: EBMYCP00000003423
EnsemblGenome: EBMYCG00000069525
EnsemblGenome_TRS: EBMYCT00000069530
EnsemblGenome_PRO: EBMYCP00000067589
GenomeReviews: AE000
Taxonomy ID 83332
Gene Starting Position 2326943
Gene Ending Position 2327500
Gene Strand (Orientation) +
Protein Name RNA polymerase sigma factor SigC
DNA Sequence 
>gi|57116681:2326943-2327500 Mycobacterium tuberculosis H37Rv, complete genome
CATGACCGCGACGGCAAGCGACGACGAGGCCGTTACCGCACTCGCCTTGTCGGCGGCCAAGGGGAACGGG
CGGGCCCTTGAGGCGTTTATCAAAGCCACCCAGCAAGACGTGTGGCGGTTCGTCGCCTATCTGTCCGACG
TGGGCAGTGCGGACGATCTCACCCAAGAGACATTCCTACGAGCGATCGGCGCCATCCCGCGGTTTTCCGC
ACGCTCCAGCGCCCGAACTTGGTTGCTGGCCATCGCGCGCCATGTCGTCGCCGATCACATCCGCCACGTC
CGATCCCGGCCCCGCACCACCCGCGGCGCGCGTCCCGAACATCTCATAGACGGCGACCGCCATGCCCGCG
GATTCGAAGACCTCGTCGAGGTAACCACGATGATCGCCGACCTAACCACCGACCAACGGGAAGCGCTGCT
GCTGACCCAGCTGCTCGGGCTGTCCTATGCGGACGCCGCGGCGGTGTGCGGCTGCCCGGTGGGCACCATC
CGATCCCGTGTCGCTCGAGCGCGCGATGCGCTGCTTGCCGACGCGGAGCCCGACGACCTCACCGGCTA
Protein Sequence 
>gi|15609206|ref|NP_216585.1| ECF RNA polymerase sigma factor SigC [Mycobacterium tuberculosis H37Rv] MTATASDDEAVTALALSAAKGNGRALEAFIKATQQDVWRFVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARGFEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLADAEPDDLTG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sigC mutant is attenuated in mice (Sun et al., 2004).
COG COG1595K, under K: Transcription
References
Sun et al., 2004: Sun R, Converse PJ, Ko C, Tyagi S, Morrison NE, Bishai WR. Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set. Molecular microbiology. 2004; 52(1); 25-38. [PubMed: 15049808].