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SP_0966

Victor ID 3287
Gene Name SP_0966
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931286
NCBI Protein GI 15900843
Locus Tag SP_0966
Protein Accession NP_345447.1
Other Database IDs UniProtKB-ID: Q97R64_STRPN
UniRef100: UniRef100_B2IPC0
UniRef90: UniRef90_B1IBC6
UniRef50: UniRef50_B1IBC6
UniParc: UPI00000C9CB2
EMBL: AE005672
EMBL-CDS: AAK75087.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025176.
EnsemblGenome_TRS: EBSTRT00000025176
EnsemblGenome_PRO: EBSTRP00000024268
GenomeReviews: AE005672_GR
KEGG: spn:SP_0966
TIGR: SP_0966
HOGENOM: HBG635182
OMA: TIIMVGR
ProtClustDB: CLSK877142
BioCyc: SPNE170187-1:SP_0966-MONOMER
Taxonomy ID 170187
Gene Starting Position 913088
Gene Ending Position 914743
Gene Strand (Orientation) -
Protein Name adherence and virulence protein A
DNA Sequence 
>gi|194172857:913088-914743 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATCAGGATTTTTTCATGGATGCAATTTTTTTGGAGTCTGGTGTGACGCGGAGGGTCTTTTGTCCTGTGTA
AGTGACAAAGCCGGGTTTTCCACCAGTTGGTTTATTGAGTTTTTTGACTTCAATCATATCTACCTGCACC
AGATTCGACAGGCGCCCTTGAGAGAAGTAGGCAGCTAACTCTGCTGCGTCTGTCTTGACTGCATCAGATG
GGTCAAGATTTCCTGAGATGACAACATGGCTTCCAGGAATGTCCTTAGCATGGAACCAAAGTTCCTCCTT
GCGGGCCATTTTAAAGGTCAATTCCTCATTTTGAAGATTGTTTCGTCCGACATAGATGATGGTTTTGCCA
TCGCTTGCTAGATATTGTTCTAGTTTTTTGCGTTTCTGGATTTTCTCCCGTTGTCTTCTGCGGATAAAAC
CTGTTTGAATCAATTCTTCACGGATTTCAGCGATTTCTTCCAGTCCAGCTTGGTTGAGGACGGTTTCTAC
ACTTTCCAGATAGAGAATAGTGGCTTTGGTTTCTTCAATCAAATCAGTCAAGTATTTGACAGCTTCTTTG
AGTTTCTGATACCGTTTAAAATAGCGTTGGGCATTCTGGTTGGGAGTCAGAGCCTTATCAAGCGCAATCA
TGATAGGTTGGTTGGTATAGTAGTTGTCTAGGATAACCTGGTCTTGGTCGTTAGGCACTTGGTGGAGGAA
GGTTGTCAGCAATTCTCCTTTTTGACGAAATTCTTCAGCGTTGTCTGTCGCCAGTAACTCTTTTTCCTGT
TTTTTGAGTTTGTGTCGGTTTTTCTGAAGTTCATTTTCAACACGACGAATCAGTTCACTGGCCTGCTGTT
TGACGCGGTCGCGCTCAGCCTTATCCTTATAGTAGGTGTCCAACAAATCAGAAAGATTTGCAAAAGGCTC
TCCCACCTGATTTGCAAAAGGAACTGGACTGAAGGAAGTCTCAGTCAAGCATGGCTTGGTTTCTTGATTG
AAAAAATTTCGGAAAGCGGAAAGTTTTTCACTAACCAGTATCCTTTCCAATTCATTTGCCGTATCGCGTC
CCAGACCTTGAAAGAGGCTTTGAAGATTTTTTGCTGTTAGTTCTTGGGTTTGCAGGATTTCAAAGAGCTT
TTCATCCTTGATAGTAAAAGGATTGAGAGATTTTGTACTTGGCGGAGCGATATAGGTCGATCCTGGAAGT
AAGGTGCGGTAGCTATTTTGTGAAAAGCCGACGTGTTTGATAACTTCGAGGATTTTATGACTGCTTTTAT
CGACCAGTAGAATATTACTGTGTTTCCCCATAATTTCGATAATCAAGGTAGCCTGGATATGGTCTCCAAT
CTCGTTTTTATTGGAAACTGTAATTTCCACAATACGGTCATTTTCCACTTGCTCAATCGACTCAATCAGG
GCCCCCTGCAAATACTTTCTCAAAACCATGATAAAGGTAGAAGGTTGAGCTGGATTTTCAAAAGTCGTTT
GGGTCAGCTGAATGCGTCCAAAAACTGGATGGGCAGAAAGGAGCAGGCGATGGCTTTGGCGATTGCTGCG
GATTTGCAAGACCAACTCTTGTTCAAAAGGCTGATTGATTTTCTGGATGCGACCATTCACTAATTCGCTT
CGCAATTCCTCAACTATGTGGTGTAAAAAAAATCCGTCAAATGACA
Protein Sequence 
>gi|15900843|ref|NP_345447.1| adherence and virulence protein A [Streptococcus pneumoniae TIGR4] MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQSHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEITVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGSTYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEKLSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQASELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILDNYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVETVLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQNEELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQVDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_0966 mutant is attenuated (Hava and Camilli, 2002).
COG COG1293K, under K: Transcription
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].