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SP_1591

Victor ID 3284
Gene Name SP_1591
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931254
NCBI Protein GI 15901433
Locus Tag SP_1591
Protein Accession NP_346037.1
Other Database IDs UniProtKB-ID: Q97PL5_STRPN
UniRef100: UniRef100_Q97PL5
UniRef90: UniRef90_D6ZME0
UniRef50: UniRef50_O84913
UniParc: UPI00000518E7
EMBL: AE005672
EMBL-CDS: AAK75677.1
RefSeq_NT: NC_003028.3
MEROPS: M24.006
EnsemblGenome: EBSTRG00000025387.
EnsemblGenome_TRS: EBSTRT00000025387
EnsemblGenome_PRO: EBSTRP00000024479
GenomeReviews: AE005672_GR
KEGG: spn:SP_1591
TIGR: SP_1591
HOGENOM: HBG545079
OMA: QNNELVL
ProtClustDB: CLSK876904
BioCyc: SPNE170187-1:SP_1591-MONOMER
Taxonomy ID 170187
Gene Starting Position 1496623
Gene Ending Position 1497705
Gene Strand (Orientation) +
Protein Name proline dipeptidase
DNA Sequence 
>gi|194172857:1496623-1497705 Streptococcus pneumoniae TIGR4 chromosome, complete genome
TATGTCTAAATTACAACAAATCCTAACATATCTTGAATCAGAAAAACTAGACGTCGCTGTCGTATCTGAC
CCCGTCACAATCAATTACCTCACTGGTTTTTACAGTGATCCCCATGAACGCCAAATGTTCCTCTTTGTCC
TAGCAGATCAGGAACCTCTCCTCTTTGTCCCAGCTCTTGAAGTAGAACGTGCAAGTAGCACCGTTTCCTT
CCCAGTAGTGGGCTATGTCGATTCTGAAAATCCATGGCAAAAAATCAAACATGCTCTTCCACAACTTGAC
TTCAAACGTGTCGCTGTTGAGTTTGACAATCTCATCTTGACCAAATACCATGGTTTGAAAACAGTTTTTG
AGACTGCTGAGTTTGACAACCTCACTCCTCGTATCCAACGCATGCGCCTCATCAAATCAGCTGATGAAGT
GCAAAAAATGATGGTTGCAGGTCTTTATGCTGACAAGGCTGTTCATGTTGGTTTTGACAATATTTCTCTT
GATAAGACTGAGACAGATATCATCGCACAAATCGACTTTGCCATGAAACGTGAAGGTTATGAAATGAGCT
TTGATACCATGGTCTTGACTGGTGATAATGCTGCGAATCCACACGGCATTCCAGCAGCTAATAAGGTTGA
AAATGATGCTCTTCTCCTCTTTGACCTGGGTGTTCTGGTCAATGGCTATGCGTCAGATATGACTCGTACA
GTCGCTGTCGGCAAACCAGACCAATTCAAGAAAGATATTTACAACTTGACTCTTGAAGCCCAACAAGCTG
CTCTTGACTTTATCAAGCCAGGTGTGACTGCTCATGAAGTGGACCGCGCTGCCCGTGAGGTCATCGAAAA
AGCTGGTTATGGTGAGTACTTCAACCACCGTCTCGGGCATGGTATCGGTATGGATGTCCATGAATTCCCA
TCTATCATGGAAGGAAACGACATGGTCATCGAAGAAGGCATGTGCTTCTCTGTTGAACCAGGTATCTATA
TCCCTGGTAAAGTCGGTGTTCGTATTGAAGACTGCGGTGTTGTTACCAAGGATGGCTTCAACCTCTTTAC
AAGCACCAGCAAAGATTTGCTTTATTTTGATTA
Protein Sequence 
>gi|15901433|ref|NP_346037.1| proline dipeptidase [Streptococcus pneumoniae TIGR4] MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFLFVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFDNLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDNISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFDLGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAAREVIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVRIEDCGVVTKDGFNLFTSTSKDLLYFD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1591 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0006E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].