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trpD

Victor ID 3267
Gene Name trpD
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931021
NCBI Protein GI 15901644
Locus Tag SP_1815
Protein Accession NP_346248.1
Other Database IDs UniProtKB-ID: TRPD_STRPN
UniRef100: UniRef100_Q04IY6
UniRef90: UniRef90_Q04IY6
UniRef50: UniRef50_Q04IY6
UniParc: UPI00000519CE
EMBL: AE005672
EMBL-CDS: AAK75888.1
RefSeq_NT: NC_003028.3
EnsemblGenome: EBSTRG00000025958
EnsemblGenome_TRS: EBSTRT00000025958
EnsemblGenome_PRO: EBSTRP00000025050
GenomeReviews: AE005672_GR
KEGG: spn:SP_1815
TIGR: SP_1815
HOGENOM: HBG559996
OMA: LGVYSPE
ProtClustDB: PRK00188
BioCyc: SPNE170187-1:SP_1815-MONOMER
Taxonomy ID 170187
Gene Starting Position 1727751
Gene Ending Position 1728755
Gene Strand (Orientation) -
Protein Name anthranilate phosphoribosyltransferase
DNA Sequence 
>gi|194172857:1727751-1728755 Streptococcus pneumoniae TIGR4 chromosome, complete genome
CTCATTTTTGGTACTCCTGTAACAGTCTGAGTTTTTCAAGGGCCTTGCCTCTAGCAATCACTTGACGGGC
CAAGGCAACCCCTTCCTTGATGCTATCAATCTTACCATTAGCATAGAAACCAAGACCAGCATTCAAGACT
GTCGTTTCCAAGAATGGACTTGCTTCGTTTTTCAGAACGCTAAGCAAAATTTCTGCATTTTCCTGAGCAT
TCCCACCACGAATATCTTCCATAGCATAGCCTTCCATTCCCAAATCCTCTGGAGTAAAGCTTGACAAGCT
GATTTCGCCATTTTCAAGAAGTGCAATCTTGGTTGTTCCGTTCAAGCCAGCTTCATCCAACCCTTCTGGT
CCAGCAACCACGATGGCACGTTTGCGACCCATATTTTTCAAAACCTGAGCTGTACTTTCTAGGAGTTCTG
GACGACTAATTCCAAGAAGCTGTGTTTCTAAAGCCATTGGATGAATCAGTGGACCAGTCAAGTTCATAAT
CGTTGGAATTCCCAATTCCAAACGAGCTGGCATGATGTATTTCATAGCTGGGTGCATATTTTTAGCGAAG
AGAAAGACGATTCCAGTTTTATCAAAGACCTTACCTAGTTCAGCTGGTTTGAGGTCAAGATTGATTCCCA
AGGCTTCGAGGACATCTGCGGAACCAGATTTAGAAGATATCGAGCGGTTACCGTGTTTGGCCATGTGAAT
ACCGCCACCAGCCAAGACAAAGGCTGCAGTTGTGGAAATATTAAAACTGAAAGACTTGTCCCCACCTGTA
CCACAGTTGTCCATGGCATCATGAATCTCAGTTGGAATATGCTGGGCATGTCCTCTCATGACTTGGGCAA
TGGCTGTGCGTTCTTCAGGTGTTTCCCCCTTCATCTTAAGAGCTAAGAGGAGAGAAGCAATCTGCGCTTC
AGTTACACGCCCAGTTACGATACGCTCAATGACATCCGTCATTTCCACACCTGATAAATTTTCAAATTTT
GCTAGTTTTTCAATAATCTCTTTCA
Protein Sequence 
>gi|15901644|ref|NP_346248.1| anthranilate phosphoribosyltransferase [Streptococcus pneumoniae TIGR4] MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trpD mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0547E, under E: Amino acid transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].