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SP_1817

Victor ID 3264
Gene Name SP_1817
Sequence Strain (Species/Organism) Streptococcus pneumoniae TIGR4
NCBI Gene ID 931018
NCBI Protein GI 15901646
Locus Tag SP_1817
Protein Accession NP_346250.1
Other Database IDs UniProtKB-ID: Q97P27_STRPN
UniRef100: UniRef100_C1CMD8
UniRef90: UniRef90_B2ISS6
UniRef50: UniRef50_Q02001
UniParc: UPI00000519D0
EMBL: AE005672
EMBL-CDS: AAK75890.1
RefSeq_NT: NC_003028.3
HSSP: P05041
EnsemblGenome: EBSTRG00000025441.
EnsemblGenome_TRS: EBSTRT00000025441
EnsemblGenome_PRO: EBSTRP00000024533
GenomeReviews: AE005672_GR
KEGG: spn:SP_1817
TIGR: SP_1817
HOGENOM: HBG507440
OMA: VDEAYDD
ProtClustDB: PRK13570
BioCyc: SPNE170187-1:SP_1817-MONOMER
Taxonomy ID 170187
Gene Starting Position 1729329
Gene Ending Position 1730690
Gene Strand (Orientation) -
Protein Name anthranilate synthase component I
DNA Sequence 
>gi|194172857:1729329-1730690 Streptococcus pneumoniae TIGR4 chromosome, complete genome
ATCATGGTCTTAGTTCTCCAATTCTAGTCATAGATTTTGCTTTGTTAATGGTTTCTTGGTATTCGTTTTG
GGCGATAGAGTCGTAGACAATCCCTGCCCCAGCCTGCACATAGGCTCTTTGATTTTTGAGAATCATGGTT
CGGATGGCGATGGCCAAATCCATATCACCCGTCGCAGACAAGTAGCCGATTGCCCCAGCGTATACTCCCC
GTTTTTCCGTTTCCAGTTCATAGATACGTCTCATCGCTCGAATCTTTGGTGCTCCAGAAACGGTTCCAGC
AGGAAGCGTTGCTTTCAAGGCATCCATGGCAGTGAGTTCTGGAAGCAAACGCCCCTTGACTACGCTGGTC
AAATGCATGACGTAGCGGAAGAGCTCCACTTCCATATACTTAGTGACTTGGACACTGGTCGTTTCAGAGA
TGCGGCCAATATCGTTACGCCCCAAGTCTACCAACATTCGATGTTCTGCTGTTTCCTTCTCATCAGAGAG
GAGGTCAGTCGCCAAGGCCTTGTCTTCTTCATCCGTAGCCCCTCTTGGTCGCGTCCCTGCAATCGGATTG
GTTGTCACGATGCCATTTTTGACAGAAACCAAACTTTCTGGACTAGCTCCGATGATTTGATAATCCCCAA
AATCATAGAAATAAAGGTAATTAGAAGGATTAGTCACGCGGAGATTTCTGTAGAAGTCAAATGGATTTCC
AGTAACTTCTGCTGAAAAACGCTGGCTGAGTACACATTGGAACATATCTCCGTTACGAATCAAGTCACGA
GCTGTTTCTACCATTCCCTCAAACTTATGTGGAGCGATATGCGGTTTGAAGTCTAACGGAGATAGATCCA
AATCTTCAAATTCATTTGGAGCAGGAATGCGTAATTCCTCAAGCACTTGGTTCAAGGATTTTTCCAAGGC
CTCTTGACTGCGCTCACTATAAAGTGCATCCTCTATGACATGTATCTTCTCCTTCTTGTGGTCAAAGACC
ATATAGCTCTCATAGACAAAGAAATGCATGTCTGGCGTCCCAATTGTATCCTCAGGGATTTGACCAATTT
CTTCATAAAGCGAAATCATATCGTAACCCACAAAACCAATGGCTCCACCACCAAAAGGTAGCTCTGAGTG
GTGCTGACTCTTATGAATCACTTCATAAAGGAAATCCAAGGGATCCCGATCAATCACTTGACCATTTTGA
TAGAGAACCCCATTTTCAAACTTAATCTCAAAAACTGGATTATAGGCTAGGATAGAAAAACGAGCTGTTT
CCTTGTCTCTCGGAATACTCTCTAAAATAACCTTATGTTGCCCCTTTAAGCGCATATAAGCCAAGATTGG
TGATAAGACATCTCCATGAATGATTCGTTCCA
Protein Sequence 
>gi|15901646|ref|NP_346250.1| anthranilate synthase component I [Streptococcus pneumoniae TIGR4] MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAYNPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISLYEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQVLEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSAEVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRPRGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRYVMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAIGYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGELRP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: SP_1817 mutant is attenuated in mice (Hava and Camilli, 2002).
COG COG0147EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Hava and Camilli, 2002: Hava DL, Camilli A. Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Molecular microbiology. 2002; 45(5); 1389-1406. [PubMed: 12207705].